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MJFF supports Ceregene's CERE-120 Phase 2 study for PD with $2.5M award

The Michael J. Fox Foundation for Parkinson's Research (MJFF) will provide $2.5 million to support Ceregene Inc.'s new Phase 2 study of CERE-120. This novel gene therapy product delivers the gene for neurturin, a potent neurotrophic (growth) factor that has shown potential to improve the status of degenerating neurons in both preclinical and clinical studies. CERE-120 has the potential to improve motor function as well as slow Parkinson's disease (PD) progression.

23 Jun 2010

Understanding HIV viral protein structure could lead to new molecular medicines: Study

The UK's National Physical Laboratory is involved in a collaborative project that is helping to further the understanding of HIV viral protein structure which could lead to new molecular medicines.

23 Jun 2010

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

OvaGene Oncology Inc., a biotechnology company specializing in the development and commercialization of personalized DNA-based diagnostics for gynecologic cancer, announced today the opening of its new clinical and research laboratory in Irvine, California. This state-of-the-art facility will serve as the central headquarters for operations, research, and molecular clinical lab testing.

23 Jun 2010

Superficial relationships lead to feelings of detachment, health-related problems

Hoarding friends on Facebook - or followers on Twitter - won't do much to stave off loneliness if those relationships lack any kind of strong connection, new research finds.

23 Jun 2010

Mice treated with XOMA 052 experiences improvement in measures associated with diabetes: Endocrinology

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced the publication of data from a mouse model of diet-induced obesity in the June, 2010 edition of the journal Endocrinology. The data showed that mice treated with XOMA 052 both prophylactically and therapeutically experienced improvement in measures associated with diabetes and cardiovascular disease including reduction in glycosylated hemoglobin levels, improvement in glucose control, improved beta-cell survival and function, and a reduction in total cholesterol without reduction in high density lipoprotein.

23 Jun 2010

Fructose makes cells mature into fat cells in belly fat, study finds

Fructose, the sugar widely used as high-fructose corn syrup in soft drinks and processed foods, often gets some of the blame for the widespread rise in obesity. Now a laboratory study has found that when fructose is present as children's fat cells mature, it makes more of these cells mature into fat cells in belly fat and less able to respond to insulin in both belly fat and fat located below the skin.

22 Jun 2010

International team obtains genome sequence of human body louse

An international team has obtained the genome sequence of the human body louse (Pediculus humanus humanus), a parasite that feeds on the blood of its host and a vector of pathogens that cause diseases such as epidemic typhus, relapsing fever and trench fever.

22 Jun 2010

Beneficial effects of LifeVantage's Protandim on DMD mouse model published in Journal of Dietary Supplements

LifeVantage Corporation, the maker of Protandim®, a patented, science-based solution to oxidative stress, announced today that a peer-reviewed manuscript was published in the Journal of Dietary Supplements examining the beneficial effects of Protandim® on a mouse model of Duchenne Muscular Dystrophy (DMD), an X-linked inherited disease affecting one in 3,500 males.

22 Jun 2010

NCI awards GeneGo Phase II SBIR grant for development of MetaMiner(Oncology) platform

GeneGo, Inc., a leading provider of databases, software and services in systems biology and chemistry, announced today that they were awarded with a Phase II SBIR grant from the National Cancer Institute (NCI) for further development of an analytical platform for translational research and data analysis in oncology.

22 Jun 2010

New study that describes sequencing and analysis of body louse genome published

A global research team led by scientists from the J. Craig Venter Institute today published a new study in the Proceedings of the National Academy of Sciences describing the sequencing and analysis of the body louse genome. Lead author, Ewen Kirkness, Ph.D., JCVI, directed the sequencing and gene-finding efforts in the project. Detailed analysis of the genome was then conducted by a large international group of 71 scientists, coordinated by Barry Pittendrigh, University of Illinois, and Professor Evgeny Zdobnov, University of Geneva Medical School.

22 Jun 2010

NIH, Wellcome Trust partner to support population-based genetic studies of disorders, communicable diseases in Africa

The National Institutes of Health, an agency of the U.S. Department of Health and Human Services, and the Wellcome Trust, a global charity based in London, today announced a partnership to support population-based genetic studies in Africa of common, non-communicable disorders such as heart disease and cancer, as well as communicable diseases such as malaria.

22 Jun 2010

Protea Biosciences, Mayoly-Spindler commence Phase I/IIA human clinical trial for new recombinant Lipase

Protea Biosciences, Inc., a leading developer of new technology for pharmaceutical research, announced today that the company, in partnership with Mayoly-Spindler, a European pharmaceutical company, has commenced a Phase I/IIA human clinical trial for a new recombinant Lipase.

22 Jun 2010

New legal, ethical framework needs to be placed around banking of human biological material: Review

A lawyer and researcher at the Johns Hopkins Berman Institute of Bioethics says a new legal and ethical framework needs to be placed around the donation and banking of human biological material, one that would more clearly define the terms of the material's use - and address donor expectations before research begins.

22 Jun 2010

Young children are skilled negotiators, says Swedish study

Young children are skilled negotiators when it comes to relationships and the content of play, reveals a thesis from the University of Gothenburg, Sweden.

22 Jun 2010

SynCon DNA vaccine shows advantages in magnitude and breadth of immune responses in non-human primates

Inovio Pharmaceuticals, Inc., a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that the peer-reviewed journal Molecular Therapy has published a paper entitled "Comparative Analysis of Immune Responses Induced by Vaccination With SIV Antigens by Recombinant Ad5 Vector or Plasmid DNA in Rhesus Macaques." The paper, co-authored by researchers from Merck, University of Pennsylvania School of Medicine, and Inovio Pharmaceuticals, notes that significant advances in the design, formulation, and delivery of DNA plasmid-based vaccines have dramatically increased their ability to induce antigen-specific immune responses.

22 Jun 2010

Michigan State University researchers analyze histiocytic sarcomas

Michigan State University veterinarians are taking part in a two-year, $5.3 million project to analyze five cancers in dogs, research that could offer new insight into canine cancer genes and their potential impact on the human form of the disease.

22 Jun 2010

Studying cells in 3-D could help develop drugs to prevent cancer from spreading: Researchers

Showing movies in 3-D has produced a box-office bonanza in recent months. Could viewing cell behavior in three dimensions lead to important advances in cancer research? A new study led by Johns Hopkins University engineers indicates it may happen. Looking at cells in 3-D, the team members concluded, yields more accurate information that could help develop drugs to prevent cancer's spread.

22 Jun 2010

Cytochrome P450 plays important role in management of high blood pressure: Researchers

Researchers have found that increasing certain proteins in the blood vessels of mice, relaxed the vessels, lowering the animal's blood pressure. The study provides new avenues for research that may lead to new treatments for hypertension.

22 Jun 2010

Novel MC4R agonist exhibits potential as new treatment for obesity, diabetes

Rhythm, a biotechnology company developing peptide therapeutics for metabolic diseases, today announced a study of obese primates treated with RM-493 showing a reversal of obesity and insulin resistance, and improvement in both heart rate and blood pressure. RM-493 is a novel peptide agonist targeting the melanocortin 4 receptor (MC4R) that is a clinical candidate for the treatment of obesity and diabetes.

22 Jun 2010

Study: Complex make-up of cells could lead to new types of medicines

A surprising discovery about the complex make-up of our cells could lead to the development of new types of medicines, a study suggests. Scientists studying interactions between cell proteins - which enable the cells in our bodies to function - have shown that proteins communicate not by a series of simple one-to-one communications, but by a complex network of chemical messages.

22 Jun 2010

Medical Science News

MJFF supports Ceregene's CERE-120 Phase 2 study for PD with $2.5M award

Understanding HIV viral protein structure could lead to new molecular medicines: Study

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

Superficial relationships lead to feelings of detachment, health-related problems

Mice treated with XOMA 052 experiences improvement in measures associated with diabetes: Endocrinology

Fructose makes cells mature into fat cells in belly fat, study finds

International team obtains genome sequence of human body louse

Beneficial effects of LifeVantage's Protandim on DMD mouse model published in Journal of Dietary Supplements

NCI awards GeneGo Phase II SBIR grant for development of MetaMiner(Oncology) platform

New study that describes sequencing and analysis of body louse genome published

NIH, Wellcome Trust partner to support population-based genetic studies of disorders, communicable diseases in Africa

Protea Biosciences, Mayoly-Spindler commence Phase I/IIA human clinical trial for new recombinant Lipase

New legal, ethical framework needs to be placed around banking of human biological material: Review

Young children are skilled negotiators, says Swedish study

SynCon DNA vaccine shows advantages in magnitude and breadth of immune responses in non-human primates

Michigan State University researchers analyze histiocytic sarcomas

Studying cells in 3-D could help develop drugs to prevent cancer from spreading: Researchers

Cytochrome P450 plays important role in management of high blood pressure: Researchers

Novel MC4R agonist exhibits potential as new treatment for obesity, diabetes

Study: Complex make-up of cells could lead to new types of medicines

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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