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Prostate cancer study identifies 295 genes associated with clinical recurrence following radical prostatectomy

Genomic Health, Inc. today announced the first results of a large prostate cancer study that identified 295 genes strongly associated with clinical recurrence following radical prostatectomy. Top-line findings from this study, which applied the same RT-PCR technology used in Genomic Health's Oncotype DX® breast and colon cancer tests, will be presented today at the Society for Urologic Oncology (SUO) annual meeting.

13 Dec 2010

UAB researchers pinpoint protein that causes nephrotic syndrome

University of Alabama at Birmingham researchers have pinpointed a protein that compromises the kidney's filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the body offers potential for treating some forms of the condition.

13 Dec 2010

Research identifies two genetic variants that increase risk of endometriosis

Research published today identifies two genetic variants that increase the risk of developing endometriosis, a common gynaecological disease. The study provides clues to the origin of this often very painful condition, which has a significant impact on the quality of life of sufferers.

13 Dec 2010

Researchers generate insulin-secreting pancreatic islet cells from human SSCs

Insulin-secreting pancreatic islet cells have been generated from human spermatogonial stem cells (SSCs) directly isolated from human testicular tissue, researchers reported today at the American Association of Cell Biology 50th Annual Meeting in Philadelphia.

13 Dec 2010

HOXB7 gene raises tamoxifen resistance in women with early-stage breast cancer

A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.

13 Dec 2010

Stem cell therapy can reduce risk of acute leukemia in affected individuals

Some adults and children with acute leukemia could benefit from certain transplants of blood stem cells, but the benefits are not equal across all cases of leukemia, according to a new review of 15 studies.

13 Dec 2010

Men with type 1 diabetes could grow their own insulin-producing cells from testicular tissue, says GUMC

Men with type 1 diabetes may be able to grow their own insulin-producing cells from their testicular tissue, say Georgetown University Medical Center (GUMC) researchers who presented their findings today at the American Society of Cell Biology 50th annual meeting in Philadelphia.

13 Dec 2010

Genetic changes in HDAC9 gene may modulate onset of ER positive breast cancer and its recurrence

Investigators at The Cancer Institute of New Jersey have presented new research at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium. Their work highlights how a variation in a person's DNA sequence is associated with an earlier age of onset for breast cancer that is stimulated by the hormone estrogen (estrogen receptor positive).

13 Dec 2010

HRT with estrogen alone may reduce risk of breast cancer: Study

While endogenous estrogen (i.e., estrogen produced by ovaries and by other tissues) does have a well-known carcinogenic impact, hormone replacement therapy (HRT) utilizing estrogen alone (the exogenous estrogen) provides a protective effect in reducing breast cancer risk, according to study results presented at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.

10 Dec 2010

Complete Genomics announces CNV and SV results as part of complete human genome sequencing service

Complete Genomics Inc. announced today that its customers will now receive copy number variation (CNV) and structural variation (SV) results as part of the CGA™ Service. This new enhancement includes additional types of variation data including quantitative, large-scale copy number measurements and larger inter- and intrachromosomal rearrangements.

10 Dec 2010

Epigenetic-molecular targeted therapy combination holds promise against advanced lung cancer

A new study shows that a combination of epigenetic therapy and molecular targeted therapy has promising results at combating advanced lung cancer according to research presented at the 2010 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is co-sponsored by the American Society for Radiation Oncology (ASTRO), the American Society of Clinical Oncology (ASCO), the International Association for the Study of Lung Cancer (ISLAC) and The University of Chicago.

10 Dec 2010

Pisgah's technology imparts abuse deterrence to commonly abused prescription drugs

Pisgah Labs announced today the findings from a proof of concept study confirming Pisgah's technology imparts abuse deterrence to commonly abused prescription drugs, particularly narcotics. The controlled study, conducted in dogs, was performed with the un-formulated active ingredient, hydrocodone, as modified according to a host of patent applications filed by Pisgah Labs with the United States Patent and Trademark Office (http://www.uspto.gov).

10 Dec 2010

First genetic test on developing risk of Alzheimer's disease and heart attacks

Alzheimer and heart attacks have been found to share common genetic basis. The research leads the way to the first genetic test on developing the risk of the diseases even at a young age. According to Federico Licastro, an immunologist at the University of Bologna who coordinated the study published in the scientific journal, Journal of Alzheimer's Disease, a test is now ready. "They are already selling it in America", he says, citing the case of a private firm in New Mexico (USA) that collaborated on the study. "But the tests could easily be also conducted wherever, using a simple blood test".

10 Dec 2010

Prometheus, UCLA collaborate to identify biological markers of mucosal healing in IBD

Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, and The Regents of the University of California, Los Angeles campus, today announced the execution of an exclusive research agreement that will focus on the identification of biological markers of mucosal healing in patients with Inflammatory Bowel Disease (IBD). The research will be led by Dr. Jonathan Braun, Chair of the Department of Pathology and Laboratory Medicine and a professor of molecular and medical pharmacology, UCLA David Geffen School of Medicine.

10 Dec 2010

Fibrin microthreads support mesenchymal stem cell growth

A research team at Worcester Polytechnic Institute has demonstrated the feasibility of a novel technology that a surgeon could use to deliver stem cells to targeted areas of the body to repair diseased or damaged tissue, including cardiac muscle damaged by a heart attack. The technique involves bundling biopolymer microthreads into biological sutures and seeding the sutures with stem cells. The team has shown that the adult bone-marrow-derived stem cells will multiply while attached to the threads and retain their ability to differentiate and grow into other cell types.

10 Dec 2010

Ambry Genetics announces launch of Illumina HiSeq 2000 Next Generation Sequencing Services

Ambry Genetics, a global leader in genomic services to the healthcare and life sciences industries, announced today that it has officially launched their Illumina HiSeq 2000 Next Generation Sequencing Services. Ambry Genetics has been an early adapter of Illumina sequencing systems since 2007 and has extensive experience as a Certified Service Provider.

10 Dec 2010

Horizon Discovery licenses new human isogenic cell models from Case Western Reserve

With the goal of developing new, more effective and personalized cancer treatments, Horizon Discovery, based in Cambridge, England, has secured from Case Western Reserve University exclusive rights to a panel of new human isogenic cell models developed by the laboratory of Zhenghe Wang, assistant professor of genetics at the university's School of Medicine.

10 Dec 2010

Celulas Genetica to submit international patent application for Rutherford Procedure

Emerging Healthcare Solutions, Inc. announced today that its newly acquired biotechnology division Celulas Genetica will submit an international patent application for the Rutherford Procedure, a revolutionary new stem-cell treatment for liver disease.

10 Dec 2010

Horizon Discovery secures exclusive rights to human isogenic cell models

With the goal of developing new, more effective and personalized cancer treatments, Horizon Discovery, based in Cambridge, England, has secured from Case Western Reserve University exclusive rights to a panel of new human isogenic cell models developed by the laboratory of Zhenghe John Wang, assistant professor of genetics at the university's School of Medicine.

10 Dec 2010

Haitian cholera pathogen closely related to 'El Tor O1' variant from South Asia

Scientists from Pacific Biosciences of California, Inc. and Harvard Medical School have successfully employed single molecule, real-time (SMRT™) DNA sequencing technology to rapidly characterize the pathogen responsible for the recent deadly cholera epidemic in Haiti. Published online Thursday in the New England Journal of Medicine, the results provide the first whole genome sequence analysis and most detailed genetic profile to date of the Haitian Vibrio cholerae outbreak strain.

10 Dec 2010

Medical Science News

Prostate cancer study identifies 295 genes associated with clinical recurrence following radical prostatectomy

UAB researchers pinpoint protein that causes nephrotic syndrome

Research identifies two genetic variants that increase risk of endometriosis

Researchers generate insulin-secreting pancreatic islet cells from human SSCs

HOXB7 gene raises tamoxifen resistance in women with early-stage breast cancer

Stem cell therapy can reduce risk of acute leukemia in affected individuals

Men with type 1 diabetes could grow their own insulin-producing cells from testicular tissue, says GUMC

Genetic changes in HDAC9 gene may modulate onset of ER positive breast cancer and its recurrence

HRT with estrogen alone may reduce risk of breast cancer: Study

Complete Genomics announces CNV and SV results as part of complete human genome sequencing service

Epigenetic-molecular targeted therapy combination holds promise against advanced lung cancer

Pisgah's technology imparts abuse deterrence to commonly abused prescription drugs

First genetic test on developing risk of Alzheimer's disease and heart attacks

Prometheus, UCLA collaborate to identify biological markers of mucosal healing in IBD

Fibrin microthreads support mesenchymal stem cell growth

Ambry Genetics announces launch of Illumina HiSeq 2000 Next Generation Sequencing Services

Horizon Discovery licenses new human isogenic cell models from Case Western Reserve

Celulas Genetica to submit international patent application for Rutherford Procedure

Horizon Discovery secures exclusive rights to human isogenic cell models

Haitian cholera pathogen closely related to 'El Tor O1' variant from South Asia

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