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Promising study may lead to potential new therapeutics for women facing triple-negative breast cancer

Using a small molecule decoy, investigators funded by the Samuel Waxman Cancer Research Foundation have managed to block protein interactions and induce epigenetic reprogramming in human and mouse breast cancer cells, essentially changing the gene expression of breast cancer cells to behave in a more normal manner.

9 Jul 2010

Males with faulty BRCA2 genes at risk of breast cancer

Men who carry a faulty version of the BRCA2 gene have an estimated one-in-15 chance of developing breast cancer by the time they reach 70, British scientists have found.

9 Jul 2010

Skandion Clinic selects IBA for installation of particle therapy facility

IBA (Ion Beam Applications S.A.) announced that Skandion Clinic, the clinical centre for proton therapy in Sweden, has selected IBA for the installation of a particle therapy facility. This new center will be managed by a consortium of seven Swedish counties, representing eight university hospitals.

9 Jul 2010

Screening for HPV genotypes 16 and 18 helps detect cervical pre-cancer missed by Pap test

Roche today announced that data from the ATHENA (Addressing THE Need for Advanced HPV Diagnostics) U.S. registration trial of over 47,000 women demonstrate that two human papillomavirus genotypes, HPV 16 and HPV 18, can identify those women with cervical pre-cancer missed by cytologic examination with a Papanicolau (Pap) test.

From Roche Sequencing and Life Science 9 Jul 2010

Musashi 2 protein predicts progression of AML and CML, identify researchers

Researchers at Whitehead Institute and Children's Hospital Boston have identified a protein, called Musashi 2, that is predictive of prognosis in acute myeloid leukemia and chronic myeloid leukemia patients.

9 Jul 2010

Research findings may help scientists understand how muscle and heart diseases develop

Researchers from Mount Sinai School of Medicine have identified a previously unknown mechanism by which cells direct gene expression, the process by which information from a gene is used to direct the physical and behavioral development of individuals. The research, which may help scientists gain insight into how muscle and heart diseases develop, is published in the July 8th issue of Nature.

9 Jul 2010

Study identifies a region in human genome that is linked to FSGS

An in-depth study of a family with multiple generations affected by kidney disease has identified a previously unknown location for a gene abnormality causing focal segmental glomerulosclerosis, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

9 Jul 2010

Female mice that lack fucose mutarotase gene exhibit male-like sexual behavior

The mammalian fucose mutarotase enzyme is known to be involved in incorporating the sugar fucose into protein. Female mice that lack the fucose mutarotase (FucM) gene refuse to let males mount them, and will attempt copulation with other female mice. Researchers writing in BioMed Central's open access journal BMC Genetics created the FucM mouse mutants in order to investigate the role of this enzyme in vivo.

9 Jul 2010

Biologists discover new way to limit formation of teratomas

One of the characteristics of embryonic stem cells is their ability to form unusual tumors called teratomas. These tumors, which contain a mixture of cells from a variety of tissues and organs of the body, are typically benign. But they present a major obstacle to the development of human embryonic stem cell therapies that seek to treat a variety of human ailments such as Parkinson's, diabetes, genetic blood disorders and spinal cord injuries.

9 Jul 2010

Researchers report how mature red blood cells form

We take our blood for granted, but its creation requires a complicated series of steps, starting with the formation of blood stem cells during early embryonic development, followed by progressive differentiation into the progenitors of red cells, white cells and platelets, and ultimately the full set of blood cells.

9 Jul 2010

Student-led team awarded top honor in 2010 CIMIT Prize in Primary Healthcare competition

Imagine finding out before you leave the pediatrician's office if your child has strep throat, or even something more serious requiring a different treatment. A novel application for applying DNA "nanobarcodes" in a clinical assay could help primary-care physicians quickly and more accurately determine what's causing a patient's acute pharyngitis from an easy throat swab.

9 Jul 2010

MicroRNA 193b gene can slow the growth of melanoma, research shows

New Queen's University research has shown that the growth of melanoma, one of the most deadly forms of skin cancer, can be slowed when a little known gene called MicroRNA 193b is added.

9 Jul 2010

Researcher uses biopharmaceutical proteases to develop novel therapy for Alzheimer's disease

A University of Oklahoma researcher is developing a novel therapy for Alzheimer's disease using "biopharmaceutical proteases" to attack the toxic plaque that builds up in the brain of an Alzheimer's patient-an approach that he predicts will be lower in cost and higher in effectiveness than current therapies.

9 Jul 2010

UKPTO grants arGEN-X patent covering SIMPLE Antibody platform

arGEN-X, a biopharmaceutical company focused on the discovery and development of human monoclonal antibodies using its proprietary SIMPLE Antibody(TM) platform, announces that it has been granted the first patent covering the platform. The patent GB2461546B, has been granted by the UK Patent and Trademark Office (UKPTO).

9 Jul 2010

Research finding uncovers alternative treatments for people with hereditary colorectal cancer

By solving the three-dimensional structure of a protein involved in repairing DNA errors, a group of McMaster University researchers have revealed new avenues to develop assessment tools and alternative treatments for people living with hereditary colorectal cancers.

9 Jul 2010

Jasmine can be used instead of sleeping pills or mood enhancers: Study

Instead of a sleeping pill or a mood enhancer, a nose full of jasmine from Gardenia jasminoides could also help: in collaboration with Dr. Olga Sergeeva and Prof. Helmut Hass from the Heinrich Heine University in Düsseldorf, researchers from Bochum led by Prof. Dr. Dr. Dr. Hanns Hatt have discovered that the two fragrances Vertacetal-coeur (VC) and the chemical variation (PI24513) have the same molecular mechanism of action and are as strong as the commonly prescribed barbiturates or propofol.

9 Jul 2010

NeuroPace submits PMA to FDA for world's first responsive neurostimulation system

NeuroPace, Inc. today announced that it has submitted its Premarket Approval (PMA) application to the U.S. Food and Drug Administration (FDA) for its RNS® System, a novel investigational device that utilizes responsive neurostimulation to monitor and interrupt abnormal electrical activity in the brain before seizures occur. The PMA application is for an indication to treat people with medically refractory partial onset epilepsy originating from one or two locations in the brain.

9 Jul 2010

Eurofins MWG Operon, Genomatix Software partner to offer next-gen sequencing solutions

Eurofins MWG Operon, an expert in next generation sequencing (NGS) and Genomatix Software GmbH, a leading company in complex analysis and interpretation of such NGS data, announce their decision to combine their expertise and join forces to offer state-of-the art solutions for comprehensive genome analysis and re-sequencing project services.

9 Jul 2010

Infinity obtains global rights to Intellikine's portfolio of inhibitors of delta and gamma isoforms of PI3K

Infinity Pharmaceuticals, Inc., an innovative drug discovery and development company, and Intellikine, Inc., a leader in the development of small molecule drugs targeting the PI3K/mTOR pathway, today announced an agreement under which Infinity obtained global development and commercialization rights to Intellikine's portfolio of inhibitors of the delta and gamma isoforms of phosphoinositide-3-kinase.

8 Jul 2010

Fibrocell Science completes enrollment in azficel-T histology study

Fibrocell Science, Inc., a biotechnology company focused on the development of autologous cell therapies for aesthetic, medical and scientific applications, announced today the completion of enrollment of and first treatment visits for participants in its histology study (IT-H-001) of azficel-T. An autologous cell therapy, azficel-T is currently under review by the U.S. Food and Drug Administration for the treatment of moderate to severe nasolabial fold wrinkles.

8 Jul 2010

Medical Science News

Promising study may lead to potential new therapeutics for women facing triple-negative breast cancer

Males with faulty BRCA2 genes at risk of breast cancer

Skandion Clinic selects IBA for installation of particle therapy facility

Screening for HPV genotypes 16 and 18 helps detect cervical pre-cancer missed by Pap test

Musashi 2 protein predicts progression of AML and CML, identify researchers

Research findings may help scientists understand how muscle and heart diseases develop

Study identifies a region in human genome that is linked to FSGS

Female mice that lack fucose mutarotase gene exhibit male-like sexual behavior

Biologists discover new way to limit formation of teratomas

Researchers report how mature red blood cells form

Student-led team awarded top honor in 2010 CIMIT Prize in Primary Healthcare competition

MicroRNA 193b gene can slow the growth of melanoma, research shows

Researcher uses biopharmaceutical proteases to develop novel therapy for Alzheimer's disease

UKPTO grants arGEN-X patent covering SIMPLE Antibody platform

Research finding uncovers alternative treatments for people with hereditary colorectal cancer

Jasmine can be used instead of sleeping pills or mood enhancers: Study

NeuroPace submits PMA to FDA for world's first responsive neurostimulation system

Eurofins MWG Operon, Genomatix Software partner to offer next-gen sequencing solutions

Infinity obtains global rights to Intellikine's portfolio of inhibitors of delta and gamma isoforms of PI3K

Fibrocell Science completes enrollment in azficel-T histology study

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

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