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Genome of Australian zebra finch decoded

Nearly all animals make sounds instinctively, but baby songbirds learn to sing in virtually the same way human infants learn to speak: by imitating a parent.

2 Apr 2010

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Renuka Iyer, MD, of the Department of Medicine, and Dan Iancu, MD, of the Department of Pathology and Laboratory Medicine at Roswell Park Cancer Institute (RPCI) are studying how a new test called CellSearch could be used with standard radiographic methods to monitor treatment results in patients with locally advanced or metastatic gallbladder or biliary duct cancers. The goal of the study is to see if CellSearch could predict patient response to therapy earlier than traditional measures.

2 Apr 2010

Nanotechnology for eavesdropping on inner electrical activity of individual cells

A nanometer-scale probe designed to slip into a cell wall and fuse with it could offer researchers a portal for extended eavesdropping on the inner electrical activity of individual cells.

2 Apr 2010

Cyclacel Pharmaceuticals' abstracts on cell cycle inhibitor drugs selected for presentation at AACR meeting

Cyclacel Pharmaceuticals, Inc. today announced that six abstracts highlighting translational and preclinical data for Cyclacel's cell cycle inhibitor drugs have been selected for presentation at the American Association of Cancer Research (AACR) Annual Meeting, being held from April 17-21, 2010, in Washington, DC.

2 Apr 2010

Multidisciplinary approach holds promise for treating patients with spinal cord injuries

Although new developments in the management of spinal cord injuries are on the horizon, any eventual cure for the condition is more likely to involve a multidisciplinary approach, drawing from expertise in several fields, according to a review article published in the April 2010 issue of the Journal of the American Academy of Orthopaedic Surgeons.

2 Apr 2010

DNA resources coupled to EMR systems hold potential as valuable tools for clinical research

A new study reveals an exciting potential benefit of the rapidly accumulating databases of health care information, the ability to make unprecedented links between genomic data and clinical medicine. The research, published by Cell Press in the April issue of the American Journal of Human Genetics, supports the idea that large scale DNA databanks linked to electronic medical record (EMR) systems provide a valuable platform for discovering, assessing and validating associations between genes and diseases.

2 Apr 2010

SwitchGear Genomics introduces GoClone miRNA research tool

SwitchGear Genomics, Inc., a leading provider of products for studying regulatory elements in the human genome, today announced the launch of a unique research tool for screening for miRNA function in living cells. The new SwitchGear GoClone™ miRNA target sets utilize experimentally-validated luciferase reporter vectors to accurately quantify human 3'UTR activity in response to a number of relevant miRNAs.

2 Apr 2010

Physicians increase prescription of new biologics

Sermo, the world's largest online community for physicians, today announced a Sermo Event Report titled "Is there any Threat to Anti-TNFs from Newer Biologic DMARDs?" In the past year, the FDA has approved four new biologic DMARDs – Actemra (Genentech), Orencia (Bristol-Myers Squibb), Simponi (Centocor Ortho Biotech), and Cimzia (UCB). According to the report, Orencia leads the pack among physicians as the next line of treatment for patients who fail two or more TNF antagonists.

2 Apr 2010

Researchers identify soy peptides that inhibit fat accumulation and reduce inflammation

If you're serious about losing weight, check out recent studies done in Elvira de Mejia's University of Illinois laboratory. Her research provides insight into the way a certain type of soy protein inhibits fat accumulation and reduces inflammation.

2 Apr 2010

Molecular mechanism behind mutation in calcium channel protein linked with night blindness

Congenital stationary night blindness, an inherited condition that affects one's ability to see in the dark, is caused by a mutation in a calcium channel protein that shuttles calcium into and out of cells. Now, researchers at the Johns Hopkins University School of Medicine have teased apart the molecular mechanism behind this mutation, uncovering a more general principle of how cells control calcium levels.

2 Apr 2010

Study promises new combination cancer therapy for drug resistance

Results reported in the April 2nd issue of the journal Cell, a Cell Press publication, reveal a new source for the drug resistance that crops up all too often and quickly in the tumors of cancer patients undergoing therapy.

2 Apr 2010

Gold nanoparticles for detecting melamine in milk

University of Miami assistant professor in the College of Engineering, Na Li and her collaborators have developed a fast, economical and easy method to detect melamine in milk. Melamine is the compound found in contaminated pet food and in tainted dairy products from China in 2007 and 2008 respectively.

2 Apr 2010

Zebra finch genetic sequence decoded: help for speech impaired round the corner say researchers

Finches have been associated with evolution since the time of Darwin. In a new development researchers have successfully decoded the compete genetic make up of the zebra finch commonly known as the "little Aussie battler" (Taeniopygia guttata).

2 Apr 2010

Hamamatsu launches FDSS/uCELL imaging plate reader for kinetic cell-based assay development

Hamamatsu has announced the release of the FDSS/uCELL, an affordable new imaging plate reader for kinetic cell-based assay development, including GPCR and ion channel research. The uCELL ("micro cell") offers a cost-effective way for biotechnology companies, research institutes, and clinical research organizations to introduce the highly reliable and advanced Hamamatsu FDSS (Functional Drug Screening System) technology to their daily operations.

2 Apr 2010

Ancient hunter-gatherers were lactose intolerant, says study

The hunter-gatherers who inhabited the southern coast of Scandinavia 4,000 years ago were lactose intolerant. This has been shown by a new study carried out by researchers at Uppsala University and Stockholm University.

2 Apr 2010

Invalidation of gene patents: ACMG celebrates US District Court ruling

The American College of Medical Genetics (ACMG), one of the original plaintiffs in the anti-gene-patenting lawsuit filed in 2009, celebrated the US District Court ruling yesterday that genes are "unpatentable."

2 Apr 2010

Gene linked to kidney cancer in children discovered

Cancer Research UK-funded scientists have identified two genes linked to Wilms' tumour - a type of childhood kidney cancer - according to research published in Clinical Cancer Research.

2 Apr 2010

Study finds potential role of NGF in islet transplantation

Islet transplantation is a promising treatment for type 1 diabetes mellitus. The promotion of angiogenesis is an important endeavor to prevent islet graft failure. Endothelial precursor cells (EPCs), a heterogeneous group originating in the hematopoietic compartment of bone marrow, have an important role in the angiogenesis of adult tissues.

2 Apr 2010

ChromaDex signs agreement for commercial development of pterostilbene from University of Mississippi and USDA

A natural products chemistry company has licensed the rights for a promising botanical compound from the University of Mississippi and the Agricultural Research Service, which is the principal intramural scientific research agency of the U.S. Department of Agriculture.

2 Apr 2010

Scientists create genetic map to identify mechanism behind heart abnormalities

Though heart disease is a major cause of disability and death, very little is understood about its genetic underpinnings. Recently, an international team of investigators at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Sanford-Burnham Medical Research Institute (Sanford-Burnham) and other organizations shed new light on the subject.

2 Apr 2010

Medical Science News

Genome of Australian zebra finch decoded

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Nanotechnology for eavesdropping on inner electrical activity of individual cells

Cyclacel Pharmaceuticals' abstracts on cell cycle inhibitor drugs selected for presentation at AACR meeting

Multidisciplinary approach holds promise for treating patients with spinal cord injuries

DNA resources coupled to EMR systems hold potential as valuable tools for clinical research

SwitchGear Genomics introduces GoClone miRNA research tool

Physicians increase prescription of new biologics

Researchers identify soy peptides that inhibit fat accumulation and reduce inflammation

Molecular mechanism behind mutation in calcium channel protein linked with night blindness

Study promises new combination cancer therapy for drug resistance

Gold nanoparticles for detecting melamine in milk

Zebra finch genetic sequence decoded: help for speech impaired round the corner say researchers

Hamamatsu launches FDSS/uCELL imaging plate reader for kinetic cell-based assay development

Ancient hunter-gatherers were lactose intolerant, says study

Invalidation of gene patents: ACMG celebrates US District Court ruling

Gene linked to kidney cancer in children discovered

Study finds potential role of NGF in islet transplantation

ChromaDex signs agreement for commercial development of pterostilbene from University of Mississippi and USDA

Scientists create genetic map to identify mechanism behind heart abnormalities

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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