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imaGenes GmbH passes certification process to qualify as Roche NimbleGen CSP for DNA Methylation Analysis

Roche NimbleGen is pleased to announce that imaGenes GmbH, located in Berlin, Germany, has passed the certification process to qualify as a Roche NimbleGen Certified Service Provider for DNA Methylation Analysis. imaGenes is a solution provider for functional genomics and proteomics with a comprehensive portfolio of high-quality services for molecular life sciences.

26 Feb 2010

Individuals who naturally lack CCR5 receptor have resistant to HIV

UCLA AIDS Institute researchers successfully removed CCR5 - a cell receptor to which HIV-1 binds for infection but which the human body does not need - from human cells. Individuals who naturally lack the CCR5 receptor have been found to be essentially resistant to HIV.

26 Feb 2010

Genetic factors influence likelihood of developing PTSD

The 1994 genocide in Rwanda resulted in the mass killing of up to one million people over the course of about 100 days. Although the exact death toll is unknown, experts estimate that as much as 20% of the country's entire population was murdered. There can be no doubt or surprise then that some of the survivors developed posttraumatic stress disorder, or PTSD, an anxiety disorder that can develop after witnessing or experiencing a traumatizing event, such as abuse, war, or natural disaster.

26 Feb 2010

Helicos BioSciences to demonstrate single molecule sequencing using Helicos Genetic Analysis System

Helicos BioSciences and it’s collaborators will deliver presentations featured at the Advances in Genome Biology and Technology (AGBT) meeting in Marco Island, Florida, from February 24-27, 2010.

26 Feb 2010

Comprehensive development strategy yields two potential drugs that block cancer-promoting pathways

A comprehensive drug development strategy that starts with extensive screening of potential targeting agents and then narrows down to a small-molecule prototype has yielded two potential drugs that block cancer-promoting pathways in novel ways, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in two papers published back-to-back online at the Proceedings of the National Academies of Science.

26 Feb 2010

Schizophrenia: Insight into late development of symptoms

In reports of two new studies, researchers led by Johns Hopkins say they have identified the mechanisms rooted in two anatomical brain abnormalities that may explain the onset of schizophrenia and the reason symptoms don't develop until young adulthood. Both types of anatomical glitches are influenced by a gene known as DISC1, whose mutant form was first identified in a Scottish family with a strong history of schizophrenia and related mental disorders. The findings could lead to new ways to treat, prevent or modify the disorder or its symptoms.

26 Feb 2010

Researchers keep wary eye on emerging tick-borne diseases in Missouri

Stories of environmental damage and their consequences always seem to take place far away and in another country, usually a tropical one with lush rainforests and poison dart frogs.

26 Feb 2010

New dietary supplement blocks triggering mechanism causing breast cell mutations

Every 13 minutes a woman loses her battle with breast cancer and in 2009 alone more than 27,000 men died from prostate cancer. These powerful statistics continue to fuel research and new developments. With tens of millions of dollars in financial support from the National Cancer Institute and the U.S. Department of Defense, scientists have identified when estrogen metabolism is out of balance it can start the process leading to breast cell mutations.

26 Feb 2010

BPA exposure during pregnancy may cause permanent reproduction problems for female offspring

Here's more evidence that "safe" plastics are not as safe as once presumed: New research published online in The FASEB Journal suggests that exposure to Bisphenol A (BPA) during pregnancy leads to epigenetic changes that may cause permanent reproduction problems for female offspring. BPA, a common component of plastics used to contain food, is a type of estrogen that is ubiquitous in the environment.

26 Feb 2010

Mathematics of sleep-wake cycle

Why can't I fall asleep? Will this new medication keep me up all night? Can I sleep off this cold? Despite decades of research, answers to these basic questions about one of our most essential bodily functions remain exceptionally difficult to answer. In fact, researchers still don't fully understand why we even sleep at all. In an effort to better understand the sleep-wake cycle and how it can go awry, researchers at Rensselaer Polytechnic Institute are taking a different approach than the traditional brain scans and sleep studies. They are using mathematics.

26 Feb 2010

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

Regulus Therapeutics Inc. today announced the establishment of a new collaboration with GlaxoSmithKline (GSK) to develop and commercialize microRNA therapeutics targeting microRNA-122 in all fields with Hepatitis C Viral infection (HCV) as the lead indication. Under the terms of the new collaboration, Regulus will receive additional upfront and early-stage milestone payments with the potential to earn more than $150 million in miR-122-related combined payments, and tiered royalties up to double digits on worldwide sales of products.

25 Feb 2010

"Hope – It's In Our Genes" rare disease campaign slogan translated into multiple international languages and Braille

The Global Genes Project (www.globalgenesproject.org), today announced that its rare disease campaign slogan, "Hope – It's In Our Genes™," has been translated into multiple international languages and Braille by rare disease patient advocates and supporters from around the world. The translation of this slogan unifies the rare disease community and global network under one banner.

25 Feb 2010

Semafore Pharmaceuticals awarded U.S. patent covering PI-3 kinase inhibitor prodrugs

Semafore Pharmaceuticals today announced today announced the United States Patent and Trademark Office (PTO) has issued United States Patent Number 7,662,977 entitled “PI-3 Kinase Inhibitor Prodrugs.” This composition of matter patent covers a genus of novel compounds that includes SF1126, Semafore’s clinical stage, small molecule inhibitor of phosphoinositide-3-kinase (PI3K) and mammalian target of rapamycin (mTOR), two key members of the PI3K signaling pathway that is vital to several essential biological processes, such as cell proliferation and survival.

25 Feb 2010

Elsevier introduces new online book series for scientific community

Elsevier, a world-leading publisher of scientific, technical, and medical information products and services, announced today the launch of Elsevier Insights, a new online book series covering topics in areas such as life and physical sciences, engineering, computer science, tourism, and finance.

25 Feb 2010

Lab research targets 'estrogen-receptor positive' breast cancer cells; identifies key protein

In a laboratory study published in the journal Cancer Research, Scott & White Healthcare anatomic pathologist Arundhati Rao, M.D. is a co-investigator looking at the ways in which estrogen can interfere with how chemotherapy does its job in destroying breast cancer cells.

25 Feb 2010

LGL awards first three grants from POC fund for research in immunotherapy, schizophrenia and heart disease

London Genetics Limited, an expert in the use of pharmacogenetics in clinical drug discovery and development, has awarded the first three grants from its proof-of-concept (POC) fund. The awards, to teams at Imperial College London and University College London, are for research in the areas of immunotherapy, schizophrenia and heart disease.

25 Feb 2010

Recovery of consciousness in traumatic brain injury patients

The recovery of consciousness following traumatic brain injury and recent advances in neuroimaging and deep brain stimulation will be discussed at the 14th Annual Swartz Foundation Mind/Brain Lecture at Stony Brook University on Monday, March 15, 2010 at 4:30 p.m. in the Staller Center for the Arts.

25 Feb 2010

Agilent Technologies announces new multiplexing capability in SureSelect Target Enrichment System

Agilent Technologies Inc. today announced that its Agilent SureSelect Target Enrichment System supports multiplexed DNA sequencing of 12 to 16 samples per lane depending on the next-generation sequencing platform, reducing costs and increasing throughput up to 16-fold.

25 Feb 2010

NIPTRC and partners announce development of new imaging process for proton beam therapy in cancer

Scientists and researchers from the Northern Illinois Proton Treatment and Research Center (NIPTRC) and Northern Illinois University along with their partners are developing a new imaging process using a proton beam that they believe will be a major medical breakthrough in the delivery of proton beam therapy for cancer patients.

25 Feb 2010

Hormone vasopressin helps brain differentiate between familiar and new scents

The study, published in the journal Nature, suggests that when the hormone fails to function, animals are unable to recognise other individuals from their scent.

25 Feb 2010

Medical Science News

imaGenes GmbH passes certification process to qualify as Roche NimbleGen CSP for DNA Methylation Analysis

Individuals who naturally lack CCR5 receptor have resistant to HIV

Genetic factors influence likelihood of developing PTSD

Helicos BioSciences to demonstrate single molecule sequencing using Helicos Genetic Analysis System

Comprehensive development strategy yields two potential drugs that block cancer-promoting pathways

Schizophrenia: Insight into late development of symptoms

Researchers keep wary eye on emerging tick-borne diseases in Missouri

New dietary supplement blocks triggering mechanism causing breast cell mutations

BPA exposure during pregnancy may cause permanent reproduction problems for female offspring

Mathematics of sleep-wake cycle

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

"Hope – It's In Our Genes" rare disease campaign slogan translated into multiple international languages and Braille

Semafore Pharmaceuticals awarded U.S. patent covering PI-3 kinase inhibitor prodrugs

Elsevier introduces new online book series for scientific community

Lab research targets 'estrogen-receptor positive' breast cancer cells; identifies key protein

LGL awards first three grants from POC fund for research in immunotherapy, schizophrenia and heart disease

Recovery of consciousness in traumatic brain injury patients

Agilent Technologies announces new multiplexing capability in SureSelect Target Enrichment System

NIPTRC and partners announce development of new imaging process for proton beam therapy in cancer

Hormone vasopressin helps brain differentiate between familiar and new scents

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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