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Advances in DNA-sequencing technology help identify your personal genome

What secrets about your risk for diseases are written in your own personal "Book of Life" - the 30,000 or so genes that make you you? Advances in DNA-sequencing technology are bringing closer the day when it will be more economical for consumers to get an answer to that question, and others, by ordering up the deciphering of their entire genetic endowment - their "personal genome."

17 Dec 2009

Study explains Salmonella's infection strategy

Salmonella are highly adaptive bacteria. They can live in the presence and absence of oxygen and thus propagate in the gut. The ingestion by humans occurs mainly via contaminated egg dishes such as mayonnaise or raw milk products as well as meat or sausages. Infections with Salmonella lead to severe diarrhea and fever, particularly in patients harbouring a compromised immune system.

17 Dec 2009

Next-generation DNA sequencing demonstrates potential in identifying mutations in SCLC

Applied Biosystems, part of Life Technologies Corporation, today announced the publication of a paper in the journal Nature that demonstrates the power of next-generation DNA sequencing used to identify DNA mutations in a small cell lung cancer (SCLC) line and identify the mutational burden associated with tobacco smoking.

17 Dec 2009

Scientists report development of technology for changing the behavior of nanoparticles

In an advance that could help ease health and environmental concerns about the emerging nanotechnology industry, scientists are reporting development of technology for changing the behavior of nanoparticles in municipal sewage treatment plants - their main gateway into the environment.

17 Dec 2009

Human embryonic stem cell lines lack genetic diversity, says study

The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according to a University of Michigan research team.

17 Dec 2009

New study shows how stem cell activity can contribute to cancer

In a developing animal, stem cells proliferate and differentiate to form the organs needed for life. A new study shows how a crucial step in this process happens and how a reversal of that step contributes to cancer.

17 Dec 2009

Typical smoker acquires one mutation for every 15 cigarettes and all cancers are caused by mutations

Research teams led by the Wellcome Trust Sanger Institute announce the first comprehensive analyses of cancer genomes.

17 Dec 2009

Scientists discover possible way to identify malignant breast tumors without biopsy

Scientists from the Kimmel Cancer Center at Jefferson have discovered a possible way for malignant breast tumors to be identified, without the need for a biopsy. The findings were published online ahead of print in the Journal of Nuclear Medicine.

17 Dec 2009

Discovery of common single-letter variant in SNP links parental origin to risk of T2D

Scientists at deCODE genetics, Inc. publish in the journal Nature the discovery of a version of a common single-letter variant in the sequence of the human genome (SNP) with a major impact on susceptibility to type 2 diabetes (T2D).

17 Dec 2009

Synthetic platelets halt blood-clotting time

Blood loss is a major cause of death from roadside bombs to freeway crashes. Traumatic injury, the leading cause of death for people age 4 to 44, often overwhelms the body's natural blood-clotting process.

17 Dec 2009

People are more prone to Crohn's disease and ulcerative colitis, explains new research

New research by the University of Adelaide could help explain why some people are more prone to Crohn's disease, ulcerative colitis and other autoimmune diseases.

17 Dec 2009

Diet rich in omega-3 fatty acids linked to improved nervous-system function

The omega-3 essential fatty acids commonly found in fatty fish and algae help animals avoid sensory overload, according to research published by the American Psychological Association.

17 Dec 2009

Researchers discover new gene involved in lung cancer using DNA sequencing technology

Aided by next-generation DNA sequencing technology, an international team of researchers has gained insights into how more than 60 carcinogens associated with cigarette smoke bind to and chemically modify human DNA, ultimately leading to cancer-causing genetic mutations.

17 Dec 2009

Researchers explore cellular movement

Our cells are more like us than we may think. They're sensitive to their environment, poking and prodding deliberately at their surroundings with hand-like feelers and chemical signals as they decide whether and where to move. Such caution serves us well but has vexed engineers who seek to create synthetic tissue, heart valves, implants and other devices that the human body will accept.

17 Dec 2009

Researchers identify genetic markers to help treat chronic kidney disease among diabetics

Researchers using a DNA analysis tool developed by the Translational Genomics Research Institute (TGen) and UCLA have identified genetic markers that could help treat chronic kidney disease among diabetics.

17 Dec 2009

Pistachios can decrease inflammation and cardiovascular disease

New research published online, December 10, 2009 indicates that bioactive compounds in pistachios, and molecules present in pistachios, have anti-inflammatory properties.

17 Dec 2009

Human MicroRNA Panel for gene-expression profiling to be launched by WaferGen Biosystems

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, today announced that it will be launching the Human MicroRNA Panel for its innovative service for gene-expression profiling using its SmartChip(TM) Real-Time PCR System.

17 Dec 2009

Medical Science News

Advances in DNA-sequencing technology help identify your personal genome

Study explains Salmonella's infection strategy

Next-generation DNA sequencing demonstrates potential in identifying mutations in SCLC

Scientists report development of technology for changing the behavior of nanoparticles

Human embryonic stem cell lines lack genetic diversity, says study

New study shows how stem cell activity can contribute to cancer

Typical smoker acquires one mutation for every 15 cigarettes and all cancers are caused by mutations

Scientists discover possible way to identify malignant breast tumors without biopsy

Discovery of common single-letter variant in SNP links parental origin to risk of T2D

Synthetic platelets halt blood-clotting time

People are more prone to Crohn's disease and ulcerative colitis, explains new research

Diet rich in omega-3 fatty acids linked to improved nervous-system function

Researchers discover new gene involved in lung cancer using DNA sequencing technology

Researchers explore cellular movement

Researchers identify genetic markers to help treat chronic kidney disease among diabetics

Pistachios can decrease inflammation and cardiovascular disease

Human MicroRNA Panel for gene-expression profiling to be launched by WaferGen Biosystems

High methionine diet may increase risk of dementia

Scientists draw on bacterial decision-making success to guide human choices on H1N1 vaccine

BUSM Pulmonary Center awarded $1.4M grant to derive stem cells and lung progenitors from lung disease patients

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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