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Targeting normal cells that surround cancer cells increases the effectiveness of traditional anti-cancer treatments

Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.

17 Nov 2009

PPD, Janssen Pharmaceutica to develop therapeutic compounds for IBS and bacterial infections

PPD, Inc. today announced it has entered an agreement with Janssen Pharmaceutica N.V. to develop and commercialize two Phase II-ready therapeutic compounds, one to treat diarrhea-predominant irritable bowel syndrome (IBS-d) and the other to treat complicated skin and skin structure and respiratory infections.

17 Nov 2009

Antioxidant found in vegetables can protect cells from damage caused by infection and injury

Scientists at the University of Pennsylvania School of Medicine discovered that a dietary antioxidant found in such vegetables as broccoli and cauliflower protects cells from damage caused by chemicals generated during the body's inflammatory response to infection and injury. The finding has implications for such inflammation-based disorders as cystic fibrosis (CF), diabetes, heart disease, and neurodegeneration.

17 Nov 2009

HDAC inhibitors: New therapy for treating breast cancer

A powerful new breast cancer treatment could result from packaging one of the newer drugs that inhibits cancer's hallmark wild growth with another that blocks a primordial survival technique in which the cancer cell eats part of itself, researchers say.

17 Nov 2009

Researchers attempt to slow the pace of infectious organisms' evolution to keep today's drugs effective

Infectious organisms that become resistant to antibiotics are a serious threat to human society. They are also a natural part of evolution. In a new project, researchers at the University of Gothenburg are attempting to find substances that can slow the pace of evolution, in order to ensure that the drugs of today remain effective into the future.

17 Nov 2009

GSK-3alpha protein: A potent, positive regulator of cardiac hypertrophy

A protein long thought to be a secondary regulator in the heart's response to stressors like hypertension actually appears to be a primary regulator according to researchers from the Center for Translational Medicine at Thomas Jefferson University.

17 Nov 2009

Mount Sinai School of Medicine to participate in Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease

Mount Sinai School of Medicine is one of 12 sites nationwide participating in the first Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease. The study is the first multicenter neurosurgical intervention in Alzheimer's research in the U.S.

17 Nov 2009

Scientists find major genetic differences between the pandemic H1N1 strain and seasonal strains

As the number of deaths related to the pandemic H1N1 virus, commonly known as "swine flu," continues to rise, researchers have been scrambling to decipher its inner workings and explain why the incidence is lower than expected in older adults.

17 Nov 2009

NIH awards $3 million grant to ASU professors for research on rapid DNA sequencing technology

Arizona State University has been awarded nearly $3 million in federal stimulus funds from the National Institutes of Health. ASU professors Stuart Lindsay and Paul Westerhoff will lead a pair of two-year, innovative projects designed to tackle challenges in the fields of rapid DNA sequencing and the potential health risks of nanotechnology.

17 Nov 2009

Sterile Insect Technique can play a vital role in malaria elimination

The Sterile Insect Technique (SIT), the release of sexually sterile male insects to wipe out a pest population, is one suggested solution to the problem of malaria in Africa. A new supplement, published in BioMed Central's open access Malaria Journal, reviews the history of the technique, and features details about aspects of its application in the elimination of malaria.

16 Nov 2009

Stem cell therapy to treat heart, lung and vascular diseases show positive results

A Florida cardiologist is using stem cell therapy to treat patients who suffer from a range of heart, lung and vascular illnesses. The results have been extraordinary.

16 Nov 2009

BrainStorm Cell's therapeutic approach has potential for treatment of neurodegenerative diseases

BrainStorm Cell Therapeutics Inc., a leading developer of adult stem cell technologies and therapeutics, is pleased to announce that the company’s therapeutic approach for treating neurodegenerative diseases, particularly ALS and Parkinson’s disease, was found to have a positive effect in a mouse model of multiple sclerosis (MS).

16 Nov 2009

Scientists develop new technique to measure brain volume loss for monitoring of Alzheimer's disease

In a study that promises to improve diagnosis and monitoring of Alzheimer's disease, scientists at the University of California, San Diego have developed a fast and accurate method for quantifying subtle, sub-regional brain volume loss using magnetic resonance imaging (MRI). The study will be published the week of November 16 in the Proceedings of the National Academy of Sciences (PNAS).

16 Nov 2009

Indefinite expansion of adult cells without recourse to stem cell intermediates possible

Is the indefinite expansion of adult cells possible without recourse to stem cell intermediates? The team led by Michael Sieweke at the Centre d'immunologie de Marseille Luminy (Université Aix-Marseille 2 / CNRS / INSERM) has proved that this is the case by achieving the ex vivo regeneration for several months of macrophages, specialized cells in the immune system.

16 Nov 2009

Tips to ensure adequate vitamin D levels

Thousands of independent studies in the past three years have revealed a strong connection between vitamin D deficiency and increased risk for a variety of serious illnesses including as many as 22 forms of cancer, heart disease, diabetes, osteoporosis and multiple sclerosis, as well as common colds and flus.

16 Nov 2009

Researchers discover new immune mechanism against viruses

Viruses are microscopically sized parasites. They plant their genes in the cells of their victim in order to 'reprogram' them. The infected cells then no longer produce what they need to live, making lots of new viruses instead.

16 Nov 2009

Second Consumer Genetics Conference to be hosted at the Hynes Convention Center

The media spotlight will shine again on Boston from June 2nd – June 4th, 2010 as the Consumer Genetics Conference, (www.consumergeneticsconference.com), hosts its yearly conference at the Hynes Convention Center.

16 Nov 2009

Postmortem genetic testing to identify genetic mutations after SUD effective in identifying risk

Targeted postmortem testing to identify genetic mutations associated with sudden unexplained death (SUD) is an effective and less expensive way to determine risk to relatives than comprehensive cardiac testing of first degree relatives, according to research presented at the American Heart Association's Scientific Sessions 2009.

16 Nov 2009

Cytoskeleton plays a critical role to bring chromosome pairs together: Study

Meiosis - the pairing and recombination of chromosomes, followed by segregation of half to each egg or sperm cell - is a major crossroads in all organisms reproducing sexually. Yet, how the cell precisely choreographs these chromosomal interactions is a long-standing question.

16 Nov 2009

Scientists find link between Alzheimer's disease and chronic heart failure

A team of U.S., Canadian and Italian scientists led by researchers at Johns Hopkins report evidence from studies in animals and humans supporting a link between Alzheimer's disease and chronic heart failure, two of the 10 leading causes of death in the United States.

16 Nov 2009

Medical Science News

Targeting normal cells that surround cancer cells increases the effectiveness of traditional anti-cancer treatments

PPD, Janssen Pharmaceutica to develop therapeutic compounds for IBS and bacterial infections

Antioxidant found in vegetables can protect cells from damage caused by infection and injury

HDAC inhibitors: New therapy for treating breast cancer

Researchers attempt to slow the pace of infectious organisms' evolution to keep today's drugs effective

GSK-3alpha protein: A potent, positive regulator of cardiac hypertrophy

Mount Sinai School of Medicine to participate in Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease

Scientists find major genetic differences between the pandemic H1N1 strain and seasonal strains

NIH awards $3 million grant to ASU professors for research on rapid DNA sequencing technology

Sterile Insect Technique can play a vital role in malaria elimination

Stem cell therapy to treat heart, lung and vascular diseases show positive results

BrainStorm Cell's therapeutic approach has potential for treatment of neurodegenerative diseases

Scientists develop new technique to measure brain volume loss for monitoring of Alzheimer's disease

Indefinite expansion of adult cells without recourse to stem cell intermediates possible

Tips to ensure adequate vitamin D levels

Researchers discover new immune mechanism against viruses

Second Consumer Genetics Conference to be hosted at the Hynes Convention Center

Postmortem genetic testing to identify genetic mutations after SUD effective in identifying risk

Cytoskeleton plays a critical role to bring chromosome pairs together: Study

Scientists find link between Alzheimer's disease and chronic heart failure

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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