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Whole genome analysis identifies 43 genetic loci contributing to lipoprotein metabolism

Using highly precise measurements of plasma lipoprotein concentrations determined by nuclear magnetic resonance spectroscopy (NMR), researchers led by Daniel Chasman at Brigham and Women's Hospital and Harvard Medical School in Boston, MA, the Framingham Heart Study in Framingham, and the PROCARDIS consortium in Stockholm, Sweden and Oxford, England performed genetic association analysis across the whole genome among 17,296 women of European ancestry from the Women's Genome Health Study.

21 Nov 2009

Study reveals effectiveness of radiation therapy in achieving local control and palliation in patients with PNTs

Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors (PNTs), despite such tumors being commonly considered resistant to radiation therapy, according to a largest of its kind study in the November 15 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

20 Nov 2009

Ligand Pharmaceuticals' SARM LGD-4033 study data presented at the Gerontology Society of America meeting

Ligand Pharmaceuticals Incorporated today announced that data from a preclinical study on its selective androgen receptor modulator (SARM) LGD-4033 was featured in a poster presentation at the 62nd Annual Meeting of the Gerontology Society of America in Atlanta. LGD-4033 exhibited desirable in vivo efficacy on skeletal muscle and bone measurements in animal models of male hypogonadism and postmenopausal osteoporosis.

20 Nov 2009

SCF founder Sabrina Cohen recognized as a WebMD 2009 Health Hero

Sabrina Cohen, founder of The Sabrina Cohen Foundation for Stem Cell Research (SCF), was just recognized as a WebMD 2009 Health Hero. She will receive national media attention with a full-page article about her personal story of triumph and courage, and shares the spotlight with celebrity movie-star, Scarlett Johansson and other Health Heroes in the November/December issue.

20 Nov 2009

Discovery of Th22 cells may help in developing effective therapies for chronic skin and respiratory diseases

The newly discovered Th22 cells are a previously unknown subset of T helper cells. T helper cells are white blood cells that help activate other immune cells when the body is infected by viruses or bacteria. At the same time they help the body to tolerate own tissue and to prevent or curb inflammation.

20 Nov 2009

University of Michigan scientists discover how SEVI works

Since the discovery in 2007 that a component of human semen called SEVI boosts infectivity of the virus that causes AIDS, researchers have been trying to learn more about SEVI and how it works, in hopes of thwarting its infection-promoting activity.

20 Nov 2009

Scientists use exome sequencing method to discover the cause of mendelian disorder

For the first time, scientists have successfully used a method called exome sequencing to quickly discover a previously unknown gene responsible for a mendelian disorder.

20 Nov 2009

Scientists anticipate new approaches in drug development to combat prion infection

The regulating protein Srebp2 drives cholesterol formation, which prions need for their propagation, in prion-infected neuronal cells. With these findings, published in the current issue of the Journal of Biological Chemistry, scientists of Helmholtz Zentrum München and Technische Universität München anticipate new approaches in drug development to combat prion infection.

20 Nov 2009

I-STEM team succeeds in recreating a whole epidermis from hES cells

Stem cell research is making great strides. This is yet again illustrated by a study carried out by the I-STEM Institute (I-STEM/ Inserm UEVE U861/AFM), published in the Lancet on 21 November 2009. The I-STEM team, directed by Marc Peschanski has just succeeded in recreating a whole epidermis from human embryonic stem cells.

20 Nov 2009

Pediatric immunologist receives prestigious annual award from American Philosophical Society

A pediatric immunologist at The Children's Hospital of Philadelphia has received a prestigious annual award from the American Philosophical Society, an organization founded in 1743 by Benjamin Franklin. Jordan S. Orange, M.D., Ph.D., received the Society's Judson Daland Prize on Nov. 13 for his contributions to research and treatment of inherited immune deficiency diseases.

20 Nov 2009

Detrimental bacterial DNA identification method for use in winemaking developed

In winemaking, grape juice is turned to wine during the fermentation process by the action of a number of essential beneficial microorganisms -namely bacteria. Sometimes, though, harmful bacteria also populate the fermentation vat, spoiling the wine in the process.

20 Nov 2009

Scientists closer to unraveling the mechanisms of gene regulation

A team led by Penn State's Ross Hardison, T. Ming Chu Professor of Biochemistry and Molecular Biology, has taken a large step toward unraveling how regulatory proteins control the production of gene products during development and growth.

20 Nov 2009

Sugar-coated polymer may offer a new solution for allergy and asthma

Scientists at Johns Hopkins and their colleagues have developed sugar-coated polymer strands that selectively kill off cells involved in triggering aggressive allergy and asthma attacks. Their advance is a significant step toward crafting pharmaceuticals to fight these often life-endangering conditions in a new way.

20 Nov 2009

GERD is an immune-mediated injury and not the result of acid burn, says new study

Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study.

20 Nov 2009

NIEHS grants $13 million for engineered nanomaterials research

The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, is increasing its investment in understanding the potential health, safety and environmental issues related to tiny particles that are used in many everyday products such as sunscreens, cosmetics and electronics. The NIEHS will award about $13 million over a two-year period, through the American Recovery and Reinvestment Act, to bolster the NIEHS's ongoing research portfolio in the area of engineered nanomaterials (ENMs).

20 Nov 2009

University of Leeds scientists' discovery could lead to new treatment route for BSE and CJD

A new treatment route for bovine spongiform encephalopathy (BSE) and its human form Creutzfeldt Jakob disease (CJD) could be a step closer thanks to a discovery by scientists at the University of Leeds.

20 Nov 2009

Workshop on "Neuroeconomics and Endocrinological Economics" organized

A workshop on "Neuroeconomics and Endocrinological Economics," to be held Nov. 20 and 21 at UC Davis, will be the first to bring together experts in neuroscience, economics and hormone physiology in one event, according to organizers.

20 Nov 2009

Particles released by car brake pads can harm lung cells: Study

Real-life particles released by car brake pads can harm lung cells in vitro. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology found that heavy braking, as in an emergency stop, caused the most damage, but normal breaking and even close proximity to a disengaged brake resulted in potentially dangerous cellular stress.

19 Nov 2009

Low-level laser therapy increases tumour growth in skin cancer

High irradiances of low-level laser therapy (LLLT) should not be used over melanomas. Researchers writing in the open access journal BMC Cancer studied the pain relieving, anti-inflammatory 'cold laser', finding that it caused increased tumour growth in a mouse model of skin cancer.

19 Nov 2009

Advanced Cell Technology files an IND with the FDA for study using embryonic stem cells to treat SMD

Advanced Cell Technology, Inc. announced today that it filed an Investigational New Drug (IND) Application with the US Food and Drug Administration (FDA) to initiate a Phase I/II multicenter study using embryonic stem cell derived retinal cells to treat patients with Stargardt’s Macular Dystrophy (SMD). Among the most common causes of untreatable blindness in the world are degenerative diseases of the retina.

19 Nov 2009

Medical Science News

Whole genome analysis identifies 43 genetic loci contributing to lipoprotein metabolism

Study reveals effectiveness of radiation therapy in achieving local control and palliation in patients with PNTs

Ligand Pharmaceuticals' SARM LGD-4033 study data presented at the Gerontology Society of America meeting

SCF founder Sabrina Cohen recognized as a WebMD 2009 Health Hero

Discovery of Th22 cells may help in developing effective therapies for chronic skin and respiratory diseases

University of Michigan scientists discover how SEVI works

Scientists use exome sequencing method to discover the cause of mendelian disorder

Scientists anticipate new approaches in drug development to combat prion infection

I-STEM team succeeds in recreating a whole epidermis from hES cells

Pediatric immunologist receives prestigious annual award from American Philosophical Society

Detrimental bacterial DNA identification method for use in winemaking developed

Scientists closer to unraveling the mechanisms of gene regulation

Sugar-coated polymer may offer a new solution for allergy and asthma

GERD is an immune-mediated injury and not the result of acid burn, says new study

NIEHS grants $13 million for engineered nanomaterials research

University of Leeds scientists' discovery could lead to new treatment route for BSE and CJD

Workshop on "Neuroeconomics and Endocrinological Economics" organized

Particles released by car brake pads can harm lung cells: Study

Low-level laser therapy increases tumour growth in skin cancer

Advanced Cell Technology files an IND with the FDA for study using embryonic stem cells to treat SMD

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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