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Virginia Tech's College student receives EPA fellowship to study effects of mercury in toads

Christine Bergeron of Old Orchard Beach, Maine, a doctoral student in Virginia Tech's College of Natural Resources, received a fellowship from the Environmental Protection Agency's (EPA) National Center for Environmental Research for her research on the reproductive success of American toads.

20 Oct 2009

Antioxidant extracts of G.biloba leaves may protect cells from radiation damage

Antioxidant extracts of the leaves of the Gingko biloba tree may protect cells from radiation damage, according to a study published in the International Journal of Low Radiation. The discovery may one day be used to help reduce side effects in cancer patients undergoing radiotherapy.

20 Oct 2009

Article evaluating StemEx therapy for leukemia and lymphoma to be published

Gamida Cell announced today the publication of an article evaluating carlecortemcel-l, the generic name of what is widely known as "StemEx", as a therapy for blood cancers such as leukemia and lymphoma.

19 Oct 2009

Scientists find cause for lupuslike disease in mice

Macrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease.

19 Oct 2009

Sigma-Aldrich launches SAGEspeed, a program for developing human disease models in rodents

Sigma-Aldrich® (Nasdaq: SIAL) today announced the launch of SAGEspeed(TM), a program to develop human disease models in rodents using its proprietary novel CompoZr(TM) Zinc Finger Nuclease (ZFN) gene editing technology (http://www.compozrzfn.com).

19 Oct 2009

Metabolic master switch sets the biological clock in body tissues

Our body's activity levels fall and rise to the beat of our internal drums-the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. Whereas the master clock in the brain is set by light, the pacemakers in peripheral organs are set by food availability. The underlying molecular mechanism was unknown.

19 Oct 2009

Research study on EGFR and HER2 expressions in BTC

The epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) are involved in the carcinogenesis of many malignancies. Therapeutic molecules targeting EGFR and HER2 have been successfully used for the treatment of colorectal, breast, lung and head and neck cancers among others.

19 Oct 2009

New 3D scaffolding technology may help grow skin and blood vessels in labs

Scientists are developing new scaffolding technology which could be used to grow tissues such as skin, nerves and cartilage using 3D spaghetti-like structures. Their research is highlighted in the latest issue of Business, the quarterly highlights magazine of the Biotechnology and Biological Sciences Research Council (BBSRC).

19 Oct 2009

First high-throughput analysis of Salmonella Typhi gene

For the first time, researchers are able to look at the need for every gene in a bacterial cell in a single experiment. The new method will transform the study of gene activity and the search for weaknesses in bacterial armouries.

19 Oct 2009

UNC scientists receive GO grant to study the human genome blueprint

Ever since the first genome sequence was published in 2001, scientists have been working to figure out what the sequence means. An analogy is walking across a desert and finding a large book in a language you don't know, then trying to figure out what the book is saying.

19 Oct 2009

Discovery may yield better understanding of protective gut-dwelling bacteria

Medical researchers have long suspected that obscure bacteria living within the intestinal tract may help keep the human immune system in balance. An international collaboration co-led by scientists at NYU Langone Medical Center has now identified a bizarre-looking microbial species that can single-handedly spur the production of specialized immune cells in mice.

19 Oct 2009

IL-2 compound ineffective against HIV-AIDS

An international research team has demonstrated that treating HIV-AIDS with interleukin-2 (IL-2) is ineffective. As a result, the researchers recommend that clinical trials on this compound be stopped.

19 Oct 2009

Breakthrough discovery by scientists may lead to a new treatment for Alzheimer's Disease

A breakthrough discovery by scientists from the Mayo Clinic in Jacksonville, FL, may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques-considered a hallmark of the disease-from patients' brains.

19 Oct 2009

Stem cell treatments could repair the kidney defects associated with Alport syndrome

Several cell-based therapy approaches could provide new treatments for patients with Alport syndrome, reports an upcoming paper in the Journal of the American Society of Nephrology (JASN). "Our study opens up many considerations of how new therapies related to the use of stem cells can be devised for our kidney patients with chronic disease," comments Raghu Kalluri, MD, PhD (Harvard Medical School, Boston, MA).

19 Oct 2009

Immune-related proteins are potential drug targets for gastric inflammation and cancer

A research team from South Korea studied the complex reaction of gastric inflammation induced by Helicobacter pylori (H pylori) in a systematic manner using a protein interaction network. Their study will be published on September 28, 2009 in the World Journal of Gastroenterology.

19 Oct 2009

Research study on cowpox virus

In the annals of medicine, Edward Jenner's 1796 vaccination of a young boy against smallpox, using fluid from cowpox blisters, remains a landmark case. In a new study, Kathryn Sykes, a researcher at Arizona State University's Biodesign Institute and her colleagues have taken a fresh look at cowpox.

19 Oct 2009

UCSC professors receive $1.8M grant under NHGRI's genome sequencing technology development programme

Oxford Nanopore Technologies congratulates our collaborators Professor Mark Akeson and Professor David Deamer of the University of California, Santa Cruz (UCSC) on receiving a grant of $1.1 million, and Professor Jene Golovchenko of the University of Harvard on receiving $745,000 following on from a previous grant of $6.5 million.

From Oxford Nanopore Technologies 19 Oct 2009

New chromosomal abnormality in acute lymphoblastic leukemia

Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia (ALL) that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children with Down syndrome.

19 Oct 2009

DKC establishes link between genetic mutation affecting telomerase function and human disease

The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. Patients with DKC experience life-threatening symptoms. Bone marrow failure increases their risk of fatal infections and cancer. Many die before the age of 30 and management of the disease is limited to trying to treat its symptoms.

19 Oct 2009

Clemson University receives a $9.3M NIH grant to establish a tissue regeneration center

Clemson University has received a $9.3 million, five-year National Institutes of Health (NIH) grant to establish a Center of Biomedical Research Excellence (COBRE) for Tissue Regeneration. Faculty from the Medical University of South Carolina and the University of South Carolina also will collaborate, providing expertise in medicine and developmental biology.

19 Oct 2009

Medical Science News

Virginia Tech's College student receives EPA fellowship to study effects of mercury in toads

Antioxidant extracts of G.biloba leaves may protect cells from radiation damage

Article evaluating StemEx therapy for leukemia and lymphoma to be published

Scientists find cause for lupuslike disease in mice

Sigma-Aldrich launches SAGEspeed, a program for developing human disease models in rodents

Metabolic master switch sets the biological clock in body tissues

Research study on EGFR and HER2 expressions in BTC

New 3D scaffolding technology may help grow skin and blood vessels in labs

First high-throughput analysis of Salmonella Typhi gene

UNC scientists receive GO grant to study the human genome blueprint

Discovery may yield better understanding of protective gut-dwelling bacteria

IL-2 compound ineffective against HIV-AIDS

Breakthrough discovery by scientists may lead to a new treatment for Alzheimer's Disease

Stem cell treatments could repair the kidney defects associated with Alport syndrome

Immune-related proteins are potential drug targets for gastric inflammation and cancer

Research study on cowpox virus

UCSC professors receive $1.8M grant under NHGRI's genome sequencing technology development programme

New chromosomal abnormality in acute lymphoblastic leukemia

DKC establishes link between genetic mutation affecting telomerase function and human disease

Clemson University receives a $9.3M NIH grant to establish a tissue regeneration center

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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