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Anti-glycan antibody positivity observed in celiac disease

Anti-microbial antibody formation has been reported in celiac disease. Relatively high positivity rates were observed for the conventional antibodies, for example, ASCA, anti-OmpW, and anti-I2, and they were known to decrease after a successful gluten free-diet. The importance of newly discovered inflammatory bowel disease-associated antibodies (including anti-glycan antibodies and anti-OMP) in celiac disease is not sure.

26 Aug 2009

TBI and NWTS to serve surgeons and hospitals by supplying transplantable tissues

TBI/Tissue Banks International, one of the nation's largest eye and tissue banking networks, and Northwest Tissue Services (NWTS), a Puget Sound Blood Center program, have entered into a partnership that will allow both organizations to more efficiently serve surgeons and hospitals that rely on them for transplantable tissue.

26 Aug 2009

Mid-career scientists receive the 2009 Julie Martin Mid-Career Awards in Aging Research

Charleen T. Chu, MD, PhD, associate professor at the University of Pittsburgh and David M. Sabatini, MD, PhD, associate professor, Massachusetts Institute of Technology, received the 2009 Julie Martin Mid-Career Awards in Aging Research. Sponsored by The Ellison Medical Foundation, the grants provide funding of $550,000 to mid-career scientists whose research has great potential in advancing understanding of basic aging and its impact on age-related diseases.

26 Aug 2009

New drug delivery system for delivering nanoparticles into the tissue

Scientists at UC Santa Barbara have discovered a potential new drug delivery system. The finding is a biological mechanism for delivery of nanoparticles into tissue. The results are published in this week's Proceedings of the National Academy of Sciences.

26 Aug 2009

Australian researchers to discover proteins that cause multiple sclerosis

Australian researchers will aim to discover the proteins that cause multiple sclerosis (MS), thanks to a new nationwide research effort. The new research project will receive funding of $1 million over four years, starting this year, under the Australian Research Council's Linkage Projects funding scheme and from MS Research Australia (MSRA), the research arm of MS Australia.

26 Aug 2009

University of Idaho researchers to develop a chemical probe technology that can treat genetic diseases

Three University of Idaho researchers will embark on an unconventional approach to DNA research as one of 20 teams chosen nationwide by federal officials for the ideas to explore scientific frontiers.

26 Aug 2009

MicroRNAs in saliva could aid in the detection of oral cancer

Researchers continue to add to the diagnostic alphabet of saliva by identifying the presence of at least 50 microRNAs that could aid in the detection of oral cancer, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.

26 Aug 2009

University of Maryland researchers perform a genome-wide association study of ADP-stimulated platelet aggregation

Patients with a certain genetic variation who received the antiplatelet drug clopidogrel had a decreased platelet response to treatment and among those who had percutaneous coronary intervention (procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries) had an increased risk of having a cardiovascular event in the following year than patients who did not have this variant, according to a study in the August 26 issue of JAMA.

25 Aug 2009

MicroRNAs present in saliva could be used to detect oral squamous cell carcinoma

A new study published by researchers at the UCLA School of Dentistry substantiates the effectiveness of measuring the microRNAs present in saliva to detect oral squamous cell carcinoma. Like hall monitors in an elementary school, microRNAs are the molecules produced by cells that simultaneously asses the behavior of multiple genes and control their activity.

25 Aug 2009

Shire collaborates with Santaris Pharma to develop Locked Nucleic Acid technology

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces today that it has entered into a research-based collaboration with Santaris Pharma A/S, a leading player in RNA-based therapeutics, to develop its proprietary Locked Nucleic Acid (LNA) technology in a range of rare diseases, thereby enabling Shire to build on its already strong competitive position for its Human Genetic Therapies (HGT) business.

25 Aug 2009

University of Manchester researchers discover kinase inhibitors for treating early-stage cancers

University of Manchester researchers found that a special type of the chemicals known as 'kinase inhibitors' opened up communication channels on the surface of cells that enabled healthy cells to 'talk' to the cancer cells.

From The University of Manchester 25 Aug 2009

Genome BC's research projects to determine efficient methods of liberating fermentable sugars from dead pine

In order to reduce the Province's greenhouse gas emissions, the BC Bioenergy Strategy is calling for greatly increased production of renewable biofuels such as ethanol, from biomass grown in BC. Two new research projects, largely funded by Genome BC, will help to answer these questions and unlock the valuable green energy found within BC's forests.

25 Aug 2009

Cytrx’s study offers a better perception of arimoclomol's mechanism of action in induced animal stroke

CytRx Corporation (NASDAQ: CYTR), a biopharmaceutical research and development company engaged in the development of high-value human therapeutics, today announced that study results demonstrated that arimoclomol exhibited both statistically significant neuroprotective and neuroregenerative effects in brain cells of animals induced with stroke, offering important insights into this drug candidate’s mechanism of action.

25 Aug 2009

OriGene Technologies releases recombinant proteins purified from HEK293 cells

OriGene Technologies, Inc. announces the release of 5,000 purified human proteins, representing the most comprehensive offering of human cell-produced human proteins.

25 Aug 2009

Field and DNA studies reveal that marine reserves aid in shark conservation measures

A long-term field and DNA study by the Institute for Ocean Conservation Science at Stony Brook University, University of Miami, Field Museum of Chicago and others has shown that young lemon sharks born at the Bimini islands, Bahamas, tend to stay near their coastal birthplace for many years.

25 Aug 2009

NIAID to establish a human immune profiling research consortium in 2010; invites grant applications

The National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health, is accepting grant applications for a new initiative to establish a consortium of human immune profiling research centers.

25 Aug 2009

Research to be conducted on bacterial microbes in space to discover new medicines

Along with supply and equipment cargo bound for the International Space Station, Space Shuttle Discovery STS-128 will carry an additional scientific payload being conducted by Austin-based Astrogenetix, the first commercial space company to use microgravity to discover the foundation of new medicines.

25 Aug 2009

Scientists cultivate multiple types of retina cells from human stem cells

A team of scientists from the University of Wisconsin-Madison School of Medicine and Public Health has successfully grown multiple types of retina cells from two types of stem cells — suggesting a future in which damaged retinas could be repaired by cells grown from the patient's own skin.

25 Aug 2009

IGC scientist receives a total grant of 1.6 million euro to conduct research on neurological mechanisms

Rui Costa, principal investigator of the Champalimaud Neuroscience Programme at the Instituto Gulbenkian de Ciencia (IGC), in Portugal, is one of only 219 recipients of the prestigious European Research Council Starting grants, out of 2503 applicants for the 2009 edition of this flagship award scheme. The grant, totalling close to 1.6 million euro, for a period of five years, will allow Rui Costa's young research team to pursue their research into the neurological mechanisms underlying goal-directed decision making behaviour, versus habit-based responses.

25 Aug 2009

INSERM researchers engineer a chimeric protein that improves stem cell engraftment

Researchers at INSERM (France) have engineered a chimeric protein that increases cell survival, migration and proliferation to improve stem cell engraftment. The results, which appear in the September 2009 issue of Experimental Biology and Medicine, show that TAT-Tpr-Met, a cell permeable form of the hepatocyte growth factor receptor can increase the number of hepatic stem cells integrated into the liver of the mouse.

24 Aug 2009

Medical Science News

Anti-glycan antibody positivity observed in celiac disease

TBI and NWTS to serve surgeons and hospitals by supplying transplantable tissues

Mid-career scientists receive the 2009 Julie Martin Mid-Career Awards in Aging Research

New drug delivery system for delivering nanoparticles into the tissue

Australian researchers to discover proteins that cause multiple sclerosis

University of Idaho researchers to develop a chemical probe technology that can treat genetic diseases

MicroRNAs in saliva could aid in the detection of oral cancer

University of Maryland researchers perform a genome-wide association study of ADP-stimulated platelet aggregation

MicroRNAs present in saliva could be used to detect oral squamous cell carcinoma

Shire collaborates with Santaris Pharma to develop Locked Nucleic Acid technology

University of Manchester researchers discover kinase inhibitors for treating early-stage cancers

Genome BC's research projects to determine efficient methods of liberating fermentable sugars from dead pine

Cytrx’s study offers a better perception of arimoclomol's mechanism of action in induced animal stroke

OriGene Technologies releases recombinant proteins purified from HEK293 cells

Field and DNA studies reveal that marine reserves aid in shark conservation measures

NIAID to establish a human immune profiling research consortium in 2010; invites grant applications

Research to be conducted on bacterial microbes in space to discover new medicines

Scientists cultivate multiple types of retina cells from human stem cells

IGC scientist receives a total grant of 1.6 million euro to conduct research on neurological mechanisms

INSERM researchers engineer a chimeric protein that improves stem cell engraftment

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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