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New methods for screening nanoparticles and interaction with human cells

Scientists have developed a screening method to examine how newly made nanoparticles - particles with dimensions on the order of billionths of a meter - interact with human cells following exposure for various times and doses.

21 Aug 2006

Investigation of the proinflammatory potential of biodegradable nanoparticle drug delivery systems in the lung

Drug developers consider the lungs to be an excellent route through which to administer drugs.

21 Aug 2006

Targeted magnetic nanoparticles may be useful in both detecting and treating metastatic breast cancer

An in-depth study of nanoparticle distribution in tumor-bearing mice has shown that targeted magnetic nanoparticles accumulate and cluster in both primary breast tumors and metastatic lesions that have developed in the lung.

21 Aug 2006

St. John's wort and polymeric nanoparticles to treat ovarian tumors using light

By combining a compound produced by the plant St. John's wort with polymeric nanoparticles, researchers at the University of Geneva in Switzerland have developed a promising method for treating ovarian tumors using light.

21 Aug 2006

RNA gene found to be one of the fastest evolving regions in human genome

Since completing the sequencing of the chimpanzee genome last year, geneticists have spent many hours comparing human DNA sequences to those of our closest evolutionary relative, looking for the differences that distinguish the two species.

16 Aug 2006

Some Yellow Jackets cause more severe allergic reactions than others

Allergists at Johns Hopkins School of Medicine have concluded that the sting severity is determined not by the calendar but by the species of insect doing the stinging.

15 Aug 2006

DNA overwinds when stretched

Most of us are familiar with the winding staircase image of DNA, the repository of a biological cell's genetic information. But few of us realize just how tightly that famous double helix is wound.

8 Aug 2006

Scientists identify gene involved in stem cell self-renewal in planaria

No matter how you slice it, the freshwater planarian possesses an amazing ability to regenerate lost body parts.

7 Aug 2006

For the first time, scientists watch neurons change in response to experience

Thanks to a new imaging system, researchers at MIT's Picower Institute for Learning and Memory have gotten an unprecedented look into how genes shape the brain in response to the environment.

6 Aug 2006

Gene family expansion can begin even before a gene is duplicated

Theoretical biologist Stephen Proulx studies gene families to explore how genomes become diverse and evolve.

6 Aug 2006

DNA of human embryonic stem cells is chemically modified in a characteristic, predictable pattern

Embryonic stem cells are derived from embryos that are undergoing a period of intense cellular activity, including the chemical addition of methyl groups to specific DNA sequences in a process known as DNA methylation.

6 Aug 2006

Construction of proteins with new mechanical properties through recombination of protein fragments

So that we can move, and so that our heart beats, we need proteins with special mechanical properties, "molecular springs", which give our tissues the necessary strength and take care of elasticity and tensibility.

1 Aug 2006

Heat treatment may zap cancer cells

Scientists believe they have discovered a clue as to why so many men with testicular cancer survive against the odds.

26 Jul 2006

Scientists characterize structure of calbindin-D28K

Scientists at North Carolina State University have effectively lifted the veil from an important protein that is linked to the prevention of neurodegenerative diseases like Alzheimer's and Huntington's.

26 Jul 2006

New idea for detecting zinc in the body with implications for illnesses

Scientists at Cardiff University have developed a bright idea for detecting zinc in the body with implications for illnesses such as cancer, diabetes and Alzheimer's disease.

25 Jul 2006

Genetic link to community makeup and ecosystem evolution

Genes of one organism not only control the characteristics of that individual but also dictate the behavior of thousands of other organisms in a community.

25 Jul 2006

Link between cell's energy use and genome health discovered

While studying how a cell keeps its genetic material intact, scientists at Johns Hopkins got busy alternately knocking out two catalysts vital to managing a yeast cell's energy.

21 Jul 2006

Precise sticking of living cells on carriers by microelectrochemical methods

The adhesion and growth of cells on solid carriers is required for many applications.

21 Jul 2006

Latest sequencing targets for NHGRI

The National Human Genome Research Institute (NHGRI) has announced several new sequencing targets including the Northern white-cheeked gibbon (Nomascus leucogenys).

19 Jul 2006