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Hybrid metal and organic nanoparticles for targeting, imaging, and treating cancer

Using a set of three biocompatible polymers and a nanoparticle containing gadolinium, a team of investigators at the Colorado School of Mines has created a nanoparticle platform that has the potential to target, image, and treat cancer.

27 Apr 2009

Nanostrings bring 'artificial noses' closer to reality

These days, chemical analysts are expected to track down even single molecules.

23 Apr 2009

Using combinatorial libraries to engineer genetic circuits advances synthetic biology

Streamlining the construction of synthetic gene networks has led a team of Boston University researchers to develop a technique that couples libraries of diversified components with computer modeling to guide predictable gene network construction without the back and forth tweaking.

22 Apr 2009

DNA of uncultured organisms sequenced using novel single cell genome sequencing approach

Scientists from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) and the Bigelow Laboratory for Ocean Sciences have assembled high quality, contamination-free draft genomes of uncultured biodegrading microorganisms using a novel single cell genome sequencing approach.

22 Apr 2009

Louse infestation calibrates immune system regulation

Some parasites can exert a moderating effect on the immune system, perhaps reducing the risk of developing immune dysfunctions like asthma, allergies and some forms of arthritis.

22 Apr 2009

Scientists challenge current views on how genes are controlled in mammals

Scientists at the Omics Science Center (OSC) of the RIKEN Yokohama Institute in Japan - along with researchers from McGill University and other institutions worldwide - are challenging current notions of how genes are controlled in mammals.

22 Apr 2009

The DNA proteome

The human genome complete sequencing project in 2003 revealed the enormous instruction manual necessary to define a human being.

22 Apr 2009

New information on molecular biology of KRas protein

KRas is one of the usual suspects in cancer. It is a protein that is mutated in 30% of human tumors and has been implicated in the regulation of many cell signalling pathways.

20 Apr 2009

Mammalian alpha-fetoprotein affects the development of rat colons

Mammalian alpha-fetoprotein (AFP) is a single-chain glycoprotein and altered serum AFP levels have been observed concurrent with aberrant growth manifestations in some congenital defects and cancer.

20 Apr 2009

DNA biosynthesis discovery could lead to better antibiotics

Combating several human pathogens, including some biological warfare agents, may one day become a bit easier thanks to research reported by a University of Iowa chemist and his colleagues in the April 16 issue of the journal Nature.

16 Apr 2009

Singapore scientists synthesize gold to shed light on cells' inner workings

Highly fluorescent gold nanoclusters for sub-cellular imaging have been synthesized by researchers at the Institute of Bioengineering and Nanotechnology (IBN), one of the research institutes of Singapore's A*STAR (Agency for Science, Technology and Research).

16 Apr 2009

Secret to night vision in nocturnal animals revealed

Researchers have discovered an important element for making night vision possible in nocturnal mammals: the DNA within the photoreceptor rod cells responsible for low light vision is packaged in a very unconventional way, according to a report in the April 17th issue of Cell , a Cell Press publication.

16 Apr 2009

Scientists use eye tracking to detect mild dementia in humans

Researchers at the Yerkes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive impairment (MCI) in humans.

15 Apr 2009

Separating the good from the bad

Scientists at MIT and Brown University studying how marine bacteria move recently discovered that a sharp variation in water current segregates right-handed bacteria from their left-handed brethren, impelling the microbes in opposite directions.

15 Apr 2009

African sleeping sickness parasite breaks its own DNA to avoid detection

The parasite Trypanosoma brucei, which causes African sleeping sickness, is like a thief donning a disguise.

15 Apr 2009

Conserved gene expression reveals our 'inner fish'

A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues.

15 Apr 2009

Chemists synthesize natural alkaloid that could have anti-cancer properties

The club moss Lycopodium serratum is a creeping, flowerless plant used in homeopathic medicine to treat a wide variety of ailments.

15 Apr 2009

Novel procedure for sequencing the human genome

Since the human genome was sequenced six years ago, the cost of producing a high-quality genome sequence has dropped precipitously.

15 Apr 2009

Scientists uncover mimicry at the molecular level that protects genome integrity

The new study, which was published on April 12, 2009, in an advanced online edition of the journal Nature Structural & Molecular Biology, draws new parallels between the Rad60 DNA repair factor and SUMO, a small ubiquitin-like modifier, which are both essential for maintaining genome stability during replication.

13 Apr 2009