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First high-res 3D structures of first mammalian GRP94 protein solved

Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers.

15 Oct 2007

Chlamydomonas reinhardtii genome holds clues for renewable energy, the environment and human health

University of Minnesota researchers contributed to a national effort to sequence the genome of an ancient, one-celled organism that will help advance research in a broad range of areas, from biofuels to restoring the environment to understanding a variety of human diseases.

12 Oct 2007

A fresh perspective to the study of cell activity

In process that is shrouded in mystery, rod-shaped bacteria reproduce by splitting themselves in two. By applying advanced mathematics to laboratory data, a team led by Johns Hopkins researchers has solved a small but important part of this reproductive puzzle.

12 Oct 2007

Scientists answer century-old developmental question

Embryologists at UCL (University College London) have helped solve an evolutionary riddle that has been puzzling scientists for over a century.

11 Oct 2007

Volcanic ash and human health - new way of estimating risk

A new, rapid and cheap way of estimating the potential risk posed to human health by volcanic ash has been devised by a Durham University expert.

10 Oct 2007

Natural selection at the genetic level

In a molecular tour de force, researchers at the University of Wisconsin-Madison have provided an exquisitely detailed picture of natural selection as it occurs at the genetic level.

10 Oct 2007

Spread of endogenous retrovirus K is similar in the DNA of humans and rhesus monkeys

According to paleontologic and molecular studies, the chimpanzee (Pan troglodytes) is the closer relative to the humans (Homo sapiens) and that both lineages had a common ancestor at 5 to 7 million years ago.

10 Oct 2007

Mathematicians help unlock secrets of the immune system

A group of scientists, led by mathematicians, has taken on the challenge of building a common model of immune responses.

10 Oct 2007

Tiny radioactive molecules provide novel way to fight colorectal cancer

Johns Hopkins scientists have developed a potentially novel way to fight colorectal cancer using tiny molecules to deliver potent barrages of radiation inside cancer cells, unlike current treatments that bind to the surface of cells and attack from the outside and cause unwanted side effects.

10 Oct 2007

Better understanding of what genomic changes paved the way for modern humans

Researchers have answered a similarly vexing (and far more relevant) genomic question: Which of the thousands of long stretches of repeated DNA in the human genome came first?

9 Oct 2007

New insight on jumping genes

Keck Graduate Institute (KGI) announced that Dr. Animesh Ray, KGI professor and director of KGI's PhD program, has published a paper in the international online journal PLoS ONE that sheds new light on the evolution of moveable genetic elements, or "jumping genes."

9 Oct 2007

In biology, polarization is a good thing

Using a molecular cellular compass, individual cells in complex organisms know which way is up or down, in epithelial cells known as apical-basal polarity.

9 Oct 2007

Carbon nanotubes show great potential for use as cellular probes

As "nanopipes" they can be used to transport liquids to or from cells and inject solutions or drugs directly into individual cells and individual organelles within the cells.

8 Oct 2007

Deep-frozen HIV specimens

The development of an HIV vaccine is hindered by the rapidity with which the virus mutates.

8 Oct 2007

The origin of mammalian network of lymphatic vessels

Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature - the network of vessels and capillaries critical to various essential housekeeping functions in the body.

4 Oct 2007

PAZAR - virtual bazaar of gene regulation data

An international team has opened a virtual bazaar, called PAZAR, which allows biologists to share information about gene regulation through individually managed 'boutiques' (data collections).

4 Oct 2007

Molecular basis of the cyanide polymorphism

That clover necklace you make for your child could well be a ring of poison.

2 Oct 2007

Scientists study folding of the brain's cortex

Engineers at Washington University in St. Louis are finding common ground between the shaping of the brain and the heart during embryonic development.

2 Oct 2007

Protein architectures provide window on the history of life

The present can tell you a lot about the past, but you need to know where to look.

2 Oct 2007

Origin of the mammalian lymphatic vasculature

In the October 1 issue of G&D, Dr. Guillermo Oliver (St. Jude Children's Research Hospital) and colleagues present new evidence to resolve a century-old debate over the origin of the mammalian lymphatic vasculature.

1 Oct 2007