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Stem cell treatments could repair the kidney defects associated with Alport syndrome

Several cell-based therapy approaches could provide new treatments for patients with Alport syndrome, reports an upcoming paper in the Journal of the American Society of Nephrology (JASN). "Our study opens up many considerations of how new therapies related to the use of stem cells can be devised for our kidney patients with chronic disease," comments Raghu Kalluri, MD, PhD (Harvard Medical School, Boston, MA).

19 Oct 2009

Immune-related proteins are potential drug targets for gastric inflammation and cancer

A research team from South Korea studied the complex reaction of gastric inflammation induced by Helicobacter pylori (H pylori) in a systematic manner using a protein interaction network. Their study will be published on September 28, 2009 in the World Journal of Gastroenterology.

19 Oct 2009

Research study on cowpox virus

In the annals of medicine, Edward Jenner's 1796 vaccination of a young boy against smallpox, using fluid from cowpox blisters, remains a landmark case. In a new study, Kathryn Sykes, a researcher at Arizona State University's Biodesign Institute and her colleagues have taken a fresh look at cowpox.

19 Oct 2009

UCSC professors receive $1.8M grant under NHGRI's genome sequencing technology development programme

Oxford Nanopore Technologies congratulates our collaborators Professor Mark Akeson and Professor David Deamer of the University of California, Santa Cruz (UCSC) on receiving a grant of $1.1 million, and Professor Jene Golovchenko of the University of Harvard on receiving $745,000 following on from a previous grant of $6.5 million.

From Oxford Nanopore Technologies 19 Oct 2009

New chromosomal abnormality in acute lymphoblastic leukemia

Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia (ALL) that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children with Down syndrome.

19 Oct 2009

DKC establishes link between genetic mutation affecting telomerase function and human disease

The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. Patients with DKC experience life-threatening symptoms. Bone marrow failure increases their risk of fatal infections and cancer. Many die before the age of 30 and management of the disease is limited to trying to treat its symptoms.

19 Oct 2009

Clemson University receives a $9.3M NIH grant to establish a tissue regeneration center

Clemson University has received a $9.3 million, five-year National Institutes of Health (NIH) grant to establish a Center of Biomedical Research Excellence (COBRE) for Tissue Regeneration. Faculty from the Medical University of South Carolina and the University of South Carolina also will collaborate, providing expertise in medicine and developmental biology.

19 Oct 2009

Research study on epileptic seizures in individuals with alcohol withdrawal syndrome

Epileptic seizures are the most dramatic and prominent aspect of the "alcohol withdrawal syndrome" that occurs when a person abruptly stops a long-term or chronic drinking habit. Researchers have shown that the flow of calcium ions into brain cells via voltage-gated calcium channels plays an important role in the generation of alcohol withdrawal seizures, because blocking this flow suppresses these seizures.

19 Oct 2009

Research study provides supportive evidence for using ATR inhibitors in cancer therapy

A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrupts tissue maintenance in mice.

19 Oct 2009

Fate Therapeutics announces human iPSC generation using a combination of small molecules

Fate Therapeutics, Inc. announced today the generation of human induced-pluripotent stem cells (iPSCs) using a combination of small molecules that significantly improves the speed and efficiency of reprogramming.

19 Oct 2009

Regulation of neurotransmitters may help treat depression

New research clarifies how neurotransmitters like norepinephrine, serotonin, and dopamine, are regulated - a finding that may help fine-tune therapies for depression.

19 Oct 2009

Findings provide new insight on skin pigmentation

The skin's pigment cells can be formed from completely different cells than has hitherto been thought, a new study from the Swedish medical university Karolinska Institutet shows. The results, which are published in the journal Cell, also mean the discovery of a new kind of stem cell.

19 Oct 2009

Psychology researchers reveal the importance of peripheral vision

Two Kansas State University psychology researchers have found that although central vision allows our eyes to discern the details of a scene, our peripheral vision is most important for telling us what type of scene we're looking at in the first place, such as whether it is a street, a mountain or a kitchen.

19 Oct 2009

Findings may yield new treatments for COPD

A genetic mutation found in four children born with multiple abnormalities may provide insight into potential treatments for newborn lung distress and chronic obstructive pulmonary disease (COPD).

19 Oct 2009

First Forerunner DNA - Prokids Scientific Group Meeting in Granada

Experts in genetic identification and criminalistics from Brazil, China, Arab Emirates, Spain, USA, Philippines, Guatemala, India, Indonesia, Mexico, Nepal, Sri Lanka, Thailand and United Nations (UNODC) will meet in Granada next October 26th and 27th to celebrate the first Forerunner DNA - Prokids Scientific Group Meeting.

19 Oct 2009

APP balance critical for normal neuronal development

New data about amyloid precursor protein, or APP, a protein implicated in development of Alzheimer's disease, suggests it also may have a positive role -- directly affecting learning and memory during brain development. So is APP good or bad? Researchers at Georgetown University Medical Center say both, and that a balance of APP is critical.

19 Oct 2009

Enzo Biochem to release a new catalog dealing with epigenetics and chromatin modification

Enzo Biochem, Inc. today said that its Life Sciences subsidiary will release a new catalog dealing with “Epigenetics & Chromatin Modification” at the Society for Neuroscience’s, Neuroscience 2009 conference, beginning October 17, 2009, in Chicago, Illinois.

15 Oct 2009

NHGRI grants BioNanomatrix $833,490 for commercial development of its NanoAnalyzer system

BioNanomatrix, Inc., a developer of breakthrough single-molecule genomic analysis technology, today announced receipt of two new supplemental grants totaling $833,490 from the National Human Genome Research Institute (NHGRI) of the U.S. National Institutes of Health (NIH). The funding is intended to support further commercial development of BioNanomatrix's nanoscale whole genome imaging and analysis platform.

15 Oct 2009

Vegetable lamb plant: New treatment for osteoporosis

The "vegetable lamb" plant - once believed to bear fruit that ripened into a living baby sheep - produces substances that show promise in laboratory experiments as new treatments for osteoporosis, the bone-thinning disease. That's the conclusion of a new study in ACS' monthly Journal of Natural Products.

15 Oct 2009

Human brains have amazing ability to be energy efficient, say researchers

Our brains, it turns out, are eco-friendly. A study published in Science and reviewed by F1000 Biology members Venkatesh Murthy and Jakob Sorensen reveals that our brains have the amazing ability to be energy efficient.

15 Oct 2009

Medical Science News

Stem cell treatments could repair the kidney defects associated with Alport syndrome

Immune-related proteins are potential drug targets for gastric inflammation and cancer

Research study on cowpox virus

UCSC professors receive $1.8M grant under NHGRI's genome sequencing technology development programme

New chromosomal abnormality in acute lymphoblastic leukemia

DKC establishes link between genetic mutation affecting telomerase function and human disease

Clemson University receives a $9.3M NIH grant to establish a tissue regeneration center

Research study on epileptic seizures in individuals with alcohol withdrawal syndrome

Research study provides supportive evidence for using ATR inhibitors in cancer therapy

Fate Therapeutics announces human iPSC generation using a combination of small molecules

Regulation of neurotransmitters may help treat depression

Findings provide new insight on skin pigmentation

Psychology researchers reveal the importance of peripheral vision

Findings may yield new treatments for COPD

First Forerunner DNA - Prokids Scientific Group Meeting in Granada

APP balance critical for normal neuronal development

Enzo Biochem to release a new catalog dealing with epigenetics and chromatin modification

NHGRI grants BioNanomatrix $833,490 for commercial development of its NanoAnalyzer system

Vegetable lamb plant: New treatment for osteoporosis

Human brains have amazing ability to be energy efficient, say researchers

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