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CHEO researchers identify protein that inhibits insulin production

One of the biggest mysteries about diabetes is why specialized cells in the pancreas stop secreting insulin, which the body needs in order to store glucose from food. A team from the Children's Hospital of Eastern Ontario (CHEO) Research Institute has identified a protein that inhibits insulin production in mice - work that offers a new way of understanding, and perhaps of one day treating, both Type 1 and Type 2 diabetes.

8 Oct 2009

Pfizer-FRSQ Innovation Fund supports genetic study of inflammatory bowel disease and cancer

The first two research projects supported by the Pfizer-FRSQ Innovation Fund will investigate differences in the genetic code for inflammatory bowel disease and metastatic colorectal cancer. This research could lead to improved diagnosis and the development of individualized treatments for these diseases. These innovative projects are marshalling multidisciplinary teams of seasoned researchers from major Quebec research institutions.

8 Oct 2009

Family and population based approaches sheds new light on the potential roles of common and rare forms of human genetic variation

In one of the first studies of its kind, an international team of researchers has uncovered a single-letter change in the genetic code that is associated with autism. The finding, published in the October 8 issue of the journal Nature, implicates a neuronal gene not previously tied to the disorder and more broadly, underscores a role for common DNA variation.

8 Oct 2009

Entest BioMedical applies for Phase II grant from National Cancer Institute

Entest BioMedical, Inc. a majority owned subsidiary of Bio-Matrix Scientific Group, Inc. announced today that it has applied for an Exploratory/Development Phase II grant from the National Cancer Institute (NCI).

8 Oct 2009

NHGRI awards Geospiza a SBIR grant to develop software systems for detecting rare mutations

Geospiza, Inc., the market leading developer of genetic analysis software, today announced the receipt of a Phase I SBIR grant for “Software Systems for Detecting Rare Mutations” from the National Human Genome Research Institute (1R43HG005297-01).

7 Oct 2009

Research study to determine association of CYP2D6 variation with tamoxifen therapy

Among women with early stage breast cancer, genetic variation of a certain enzyme appears to be associated with clinical outcomes for women treated with tamoxifen, according to a study in the October 7 issue of JAMA.

7 Oct 2009

aTyr Pharma to discuss aminoacyl tRNA synthetases at the BioPartnering Europe Conference

aTyr Pharma, Inc., a biopharmaceutical company discovering and developing a new class of naturally occurring proteins as biotherapeutics, will present at the BioPartnering Europe Conference in London on Monday October 12. Jeff Watkins, CEO of aTyr Pharma, will provide an overview of aTyr Pharma's technology, product engine, and lead program based on naturally occurring resected proteins of the tRNA synthetases.

7 Oct 2009

Study reveals large structural differences between natural prions and man-made synthetic analogs

A collaboration between scientists at Vanderbilt University and the University of California, San Francisco has led to the first direct information about the molecular structure of prions. In addition, the study has revealed surprisingly large structural differences between natural prions and the closest synthetic analogs that scientists have created in the lab.

7 Oct 2009

Scientific community must fight misconceptions about experiments using animals: Researchers

In a recent commentary, We must face the threats, in the Journal of Neuroscience, researchers Dario Ringach and David Jentsch spoke out against animal rights extremism. They urged the scientific community to stand together and fight misconceptions about experiments using animals. That their plea has been heard is clear from the unanimously positive response it received on the Faculty of 1000 Biology website.

7 Oct 2009

Scientists develop new molecule that can deliver genetic-based drugs into cells

Theresa M. Reineke, associate professor of chemistry in the College of Science, and colleagues in her lab at Virginia Tech and at the University of Cincinnati have developed a new molecule that can travel into cells, deliver genetic cargo, and packs a beacon so scientists can follow its movements in living systems.

7 Oct 2009

Vitro Diagnostics' research reveals expanded uses of its fluorescent stem cells

Vitro Diagnostics, Inc., dba Vitro Biopharma, announced completion of a research report concerning its fluorescent stem cells, http://www.vitrobiopharma.com/wp-content/uploads/2009/10/fluorescent-msc-10-3.pdf. This report revealed transfer of fluorescent to differentiated cells including chondrocytes, cells responsible for making cartilage.

7 Oct 2009

Brain's mapping system uncovered

Through the power of Google Earth, you can travel the globe from the comfort of your computer screen, peering down on everything from above. But once you change your perspective - if you go into one of the buildings that you've looked down on - you have to upload a new map.

7 Oct 2009

Call for new policies on access to biobanked children's DNA

Scientists look for clues about therapies and cures for life-threatening childhood illnesses in children's DNA -- it seems only logical to do so. But the decision as to who should have access to DNA samples from children provides a unique ethical conundrum, says a Tel Aviv University researcher in a recent publication for the esteemed journal Science, co-authored by colleagues from The Netherlands and Canada.

7 Oct 2009

Researchers show that DNA methylation plays a crucial role for cancer stem cells

During cell division, whether hematopoietic stem cells (HSCs) will develop into new stem cells (self-renewal) or differentiate into other blood cells depends on a chemical process called DNA methylation.

7 Oct 2009

Research and development using stem cells from menstrual blood helps fight against breast cancer

Cryo-Cell International, a global leader in stem cell innovation, is proud to be making progress in the fight against breast cancer through research and development using stem cells from menstrual blood.

7 Oct 2009

New study leads to the development of first prophylactic treatment for leishmania

Leishmania is a deadly parasitic disease that affects over 12 million people worldwide, with more than 2 million new cases reported every year. Until recently, scientists were unsure exactly how the parasite survives inside human cells. That mystery has now been solved according to a new study published in Science Signaling by a team led by Dr. Martin Olivier - a scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University.

7 Oct 2009

NIH awards NeoStem a GO grant to investigate the potential of stem cells in regenerating bone

NeoStem, Inc. (NYSE Amex: NBS), which is pioneering the pre-disease collection, processing and long-term storage of adult stem cells for future medical need and holder of the exclusive, worldwide license to VSEL(TM) Technology that uses very small embryonic-like stem cells isolated from peripheral blood, announced today that it has been awarded a grant of $108,746 for the repair of bone defects by human stem cells under the American Recovery and Reinvestment Act (RRA) of 2009 from the National Institute of Arthritis and Musculoskeletal and Skin Disease (NIAMS) of the National Institutes of Health (NIH).

7 Oct 2009

Gene mutation linked to age-related hearing loss

Patients who exhibited a certain genetic mutation of anti-oxidant enzymes are three times more likely to develop age-related hearing loss (ARHL), according to new research presented at the 2009 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in San Diego, CA.

7 Oct 2009

Resveratrol may help improve diet-induced diabetes

Resveratrol, a molecule found in red grapes, has been shown to improve diabetes when delivered orally to rodents. Until now, however, little has been known about how these beneficial changes are mediated in the body.

6 Oct 2009

PDS Biotechnology's Versamune-based immunotherapy drug demonstrates safety in preclinical studies

PDS Biotechnology Corporation today announced that the company has completed GLP toxicology studies of its lead HPV-cancer product. The studies, which included pharmacokinetic (PK) and adsorption, bio-distribution and excretion (ADE) studies in addition to the evaluation of toxicity, all demonstrated a very safe profile of the drug and PDS Biotech's platform Versamune((TM)) technology.

6 Oct 2009

Medical Science News

CHEO researchers identify protein that inhibits insulin production

Pfizer-FRSQ Innovation Fund supports genetic study of inflammatory bowel disease and cancer

Family and population based approaches sheds new light on the potential roles of common and rare forms of human genetic variation

Entest BioMedical applies for Phase II grant from National Cancer Institute

NHGRI awards Geospiza a SBIR grant to develop software systems for detecting rare mutations

Research study to determine association of CYP2D6 variation with tamoxifen therapy

aTyr Pharma to discuss aminoacyl tRNA synthetases at the BioPartnering Europe Conference

Study reveals large structural differences between natural prions and man-made synthetic analogs

Scientific community must fight misconceptions about experiments using animals: Researchers

Scientists develop new molecule that can deliver genetic-based drugs into cells

Vitro Diagnostics' research reveals expanded uses of its fluorescent stem cells

Brain's mapping system uncovered

Call for new policies on access to biobanked children's DNA

Researchers show that DNA methylation plays a crucial role for cancer stem cells

Research and development using stem cells from menstrual blood helps fight against breast cancer

New study leads to the development of first prophylactic treatment for leishmania

NIH awards NeoStem a GO grant to investigate the potential of stem cells in regenerating bone

Gene mutation linked to age-related hearing loss

Resveratrol may help improve diet-induced diabetes

PDS Biotechnology's Versamune-based immunotherapy drug demonstrates safety in preclinical studies

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