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Tumour suppressor gene family may be key to new colon cancer drugs

In the hunt for new cancer drug targets, scientists from the Johns Hopkins Kimmel Cancer Center and the Howard Hughes Medical Institute have discovered mutations in a family of genes linked to more than a quarter of colon cancers, as well as several other common cancers including breast and lung.

20 May 2004

Scientists believe that the dog genome holds a wealth of information that will benefit human health

Recently completed genetic analysis reveals that half of the more than 300 inherited canine disorders — including a number of cancers — resemble specific diseases of man; many scientists believe that the dog genome holds a wealth of information that will benefit human health.

20 May 2004

Natural biological process by which yeast cells dismantle amyloid fibers

Amyloid fibers, those clumps of plaque-like proteins that clog up the brains of Alzheimer's patients, have perplexed scientists with their robust structures. In laboratory experiments, they are able to withstand extreme heat and cold and powerful detergents that cripple most other proteins.

20 May 2004

Scientists have sped up a common jumping gene found in the human genome

Johns Hopkins scientists have transformed a common "jumping gene" found in the human genome into one that moves hundreds of times more often than normal in mouse and human cells.

20 May 2004

Scientists have taken the first steps towards producing a sustainable and pure source of the healthy fats found in oily fish

Eating such fish is encouraged as part of a healthy diet as their oils are rich in very long chain polyunsaturated fatty acids (VLCPUFAs). However, views on the health-promoting nature of VLCPUFAs have to be balanced against the marine pollution that can cause fish, and the oils extracted from them, to be contaminated with heavy metals and dioxins, and the fact that fish stocks are in global decline.

20 May 2004

Bone repair using breakthrough material

A breakthrough in polymer development means that soon there may be a radical new treatment for people with broken bones - a special kind of material that can 'glue' the bone back together and support it while it heals. The polmer material is designed to break down as the bone regrows leaving only natural tissue.

20 May 2004

Scientists may have figured out how to use stem cells to regenerate lost or injured tissue

In experiments with fruit flies, Johns Hopkins scientists have restored the insect's sperm-making stem cells by triggering cells on the way to becoming sperm to reverse course. The unexpected findings are described in the May 13 issue of Science.

19 May 2004

Launch of Crucial Genetics, a state-of-the-art genetic profiling service

The University of Glasgow has linked up with venture capital company Fifty-Six Ltd. to launch Crucial Genetics, a state-of-the-art genetic profiling service. The company is based within customised laboratory facilities at the Southern General Hospital, Glasgow and is equipped with the latest automated fluorescent DNA laser scanning machinery.

19 May 2004

Office of Naval Research harnessing human brain power to control the maneuvers of UUVs

Even the least graceful among us has motor control the most high-tech unmanned undersea vehicle would envy, thanks to a region of the brain that allows our bodies to carry out complex maneuvers. The Office of Naval Research, which traditionally relies on the power of the human mind to achieve breakthroughs in science and technology, now also is harnessing the working principle of the brain to control the maneuvers of UUVs.

19 May 2004

Scientists move closer toward treatment for degenerative diseases

Scientists at McGill University's Faculty of Medicine have discovered a key step that will provide new targets for treatments of many degenerative diseases such as Alzheimer's, Cystic Fibrosis and Diabetes.

17 May 2004

Howard Hughes Medical Institute is awarding $49.7 million in science grants

Colleges face a number of tough challenges in teaching science today. New fields that blur the lines between disciplines are emerging, and biologists, chemists, physicists and mathematicians are forging interdisciplinary collaborations. Scientists trained to be outstanding researchers need to learn to be outstanding teachers. More minorities must be encouraged to pursue scientific careers.

17 May 2004

Scientists have identified a compound that halts the activity of a deadly toxin called anthrax

University of Chicago scientists have identified a compound that halts the activity of a deadly toxin called anthrax lethal factor in laboratory tests. Nature Biotechnology will publish the findings online on May 16 and in the June issue of the journal's print edition.

17 May 2004

Suprachiasmatic nucleus brain tissue sheds light on jet lag

New research led by a University of Washington biologist demonstrates that there are at least two circadian clocks in the mammal brain, one that sticks strictly to an internal schedule and another that can be altered by external influences such as light and dark.

12 May 2004

Expert panel to review toxicity associated with exposure to acrylamide

The National Institute of Environmental Health Sciences (NIEHS), one of the National Institutes of Health (NIH), will hold an expert panel meeting May 17-19, in Alexandria, Virginia, to review the scientific evidence regarding the potential reproductive and/or developmental toxicity associated with exposure to acrylamide.

10 May 2004

Scientists closer to a potential vaccine or treatment for botulism

By deciphering the near atomic-level structure of the catalytic domain of botulinum toxin type E — one of seven neurotoxins that cause botulism, a disease that paralyzes victims by blocking nerve cells’ ability to communicate — scientists at the U.S. Department of Energy’s Brookhaven National Laboratory are one step closer to a potential vaccine or treatment.

10 May 2004

Vegetables yield anticancer chemical

Plant chemicals created during the preparation of some vegetables could kill colon cancer cells in a similar way to some cancer drugs.

10 May 2004

Scientists discover what could be the instruction manual of life

In a world first, scientists from The University of Queensland’s Institute for Molecular Bioscience (IMB) have uncovered a new class of genetic elements with the potential to radically alter our notions of how the genome “comes to life” to form humans.

8 May 2004

Discovery of immune system malfunction that plays a profound role in food allergy

A team of scientists, led by the Institute of Food Research (IFR) in the UK, has discovered an immune system malfunction that is likely to play a profound role in food allergy.

8 May 2004

Genetic breakthrough in tracing the cause of a rare kidney and liver disorder

Birmingham scientists have made a genetic breakthrough in tracing the cause of a rare kidney and liver disorder. ARC syndrome means babies are born with impairment to kidney and liver function, bleeding problems and weak muscles. This usually leads to early death. The gene which causes this condition has been identified.

8 May 2004

New way by which cells can become cancerous may solve mystery with lung cancer

Researchers at The University of Texas M. D. Anderson Cancer Center are describing an entirely new way by which cells can become cancerous. And they say their finding provides an answer to a mystery in lung and other cancers.

8 May 2004