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Scientists visualize the machinery of mRNA splicing

Recent research at Yale provided a glimpse of the ancient mechanism that helped diversify our genomes; it illuminated a relationship between gene processing in humans and the most primitive organisms by creating the first crystal structure of a crucial self-splicing region of RNA.

7 Apr 2008

Special journal section explores geriatric assessment

The latest issue of The Journal of Gerontology: Medical Sciences (Vol. 63, No. 3) features a special section devoted to the phenomenon of multidimensional geriatric assessment - an interdisciplinary diagnostic process to determine the medical, psychological, and functional status of at-risk and frail elderly patients in order to develop a coordinated, integrated plan for treatment and long-term follow-up.

7 Apr 2008

Reconstructing mandibular defects with bioengineered tooth and bone

Current strategies for jaw reconstruction require multiple procedures, first to repair the bone defect to offer sufficient support, and then to place the tooth implant.

7 Apr 2008

Mouse calls help search for emotion-controlling genes

Scientists have long known that emotions and other personality traits and disorders run together in families.

3 Apr 2008

Surviving without sex - Bdelloid rotifers do!

Birds and bees may do it, but the microscopic animals called bdelloid rotifers seem to get along just fine without sex, thank you.

3 Apr 2008

Human-animal hybrid embryos could lead to new stem-cell treatments

British scientists say they have created human-animal "hybrid" embryos which could be used to develop new stem-cell treatments.

2 Apr 2008

Y chromosome provides new insights into human ancestry

The Y chromosome retains a remarkable record of human ancestry, since it is passed directly from father to son.

2 Apr 2008

Do humans hear better than animals?

It is known that various species of land and water-based living creatures are capable of hearing some lower and higher frequencies than humans are capable of detecting.

2 Apr 2008

From algae to parasites: new 'missing link' species found in Sydney Harbour

It's not often that brown algae is considered exciting or revolutionary, but Associate Professor Dee Carter from the School of Molecular and Microbial Biosciences at the University of Sydney and her former PhD student, Robert Moore, have found a new species of single-celled brown algae that is an evolutionary missing link.

2 Apr 2008

Researcher discovers pathway plants use to fight back against pathogens

Plants are not only smart, but they also wage a good fight, according to a University of Missouri biochemist. Previous studies have shown that plants can sense attacks by pathogens and activate their defenses.

1 Apr 2008

Tasmanian devil Cedric could save his species

Tasmanian devils, the world's largest marsupial carnivores, are a species facing extinction because of an ugly disfiguring cancer, known as devil facial tumour disease or DFTD.

1 Apr 2008

Femtogram-level chemical measurements now possible

Finding a simple and convenient technique that combines nanoscale structural measurements and chemical identification has been an elusive goal.

31 Mar 2008

Researchers examine human embryonic stem cell genome

Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.

31 Mar 2008

International team of scientists discover clue to delay of life on Earth

Scientists from around the world have reconstructed changes in Earth's ancient ocean chemistry during a broad sweep of geological time, from about 2.5 to 0.5 billion years ago.

28 Mar 2008

Beetle genome opens the door to developmental research

The whole DNA sequence of the red flour beetle, familiar to many as an unwelcome visitor to the kitchen flour jar, has been published in Nature .

28 Mar 2008

New method of filming blood-vessel cells

A new method of filming blood-vessel cells that move in accordance with targeted signals has been developed by researchers at Uppsala University in collaboration with researchers at the University of California.

28 Mar 2008

New nanoparticles for targeting tumors

As a wide variety of nanoparticles continue to demonstrate their ability to improve the delivery of imaging agents and drugs to tumors, nanoparticle researchers have turned their attention to the challenge of systematically determining how a given nanoparticle’s physical and chemical characteristics affect its ability to target tumors. Such data could provide drug developers with guidelines to help them select the most effective type of nanoparticle for a given therapeutic or imaging application.

28 Mar 2008

Anticancer siRNA therapy advances, thanks to nanoparticles

Small pieces of nucleic acid, known as siRNAs (short interfering RNAs), can turn off the production of specific proteins, a property that makes them one of the more promising new classes of anticancer drugs in development. Indeed, at least two siRNA-based anticancer therapies, both delivered to tumors in nanoparticles, have begun human clinical trials. Now, three new reports highlight the progress that researchers are making in developing broadly applicable, nanoparticle-enabled siRNA anticancer therapeutics.

28 Mar 2008

Astrotechnology brings nanoparticle probes into sharper focus

While pondering the challenges of distinguishing one nanosize probe image from another in a mass of hundreds or thousands of nanoprobes, two investigators at Emory University and the Georgia Institute of Technology made an interesting observation. The tiny, clustered dots of light looked a lot like a starry sky on a clear night.

27 Mar 2008