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PPARs and PROTACs: A new strategy in cancer therapeutics

The growing challenge in cancer therapy lies in overcoming tumor heterogeneity, drug resistance, and associated side effects.

13 Sep 2024

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy.

13 Sep 2024

Breakthrough in understanding formaldehyde toxicity during development and aging

AMeD syndrome is a severe genetic condition found in children that present with accelerated aging, global developmental delay and bone marrow failure, among others, progressing to Myelodysplastic Syndrome and Acute Myeloid Leukaemia.

13 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

New blood test achieves 98% accuracy in diagnosing ALS

A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that effects neurons in the brain and spinal cord.

13 Sep 2024

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the nomination of ISM2196, an AI-driven, potential best-in-class small molecule WRN inhibitor targeting advanced metastatic microsatellite instability (MSI) cancers guided by synthetic lethality strategy.

13 Sep 2024

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

A new editorial was recently published in Oncotarget's Volume 15, on July 10, 2024, entitled, "The advances in targeting CD47/SIRPα "do not eat me" axis and their ongoing challenges as an anticancer therapy."

13 Sep 2024

Study finds brain synchronization between humans and dogs during social interactions

During social interactions, the activity of the brain's neurons becomes synchronized between the individuals involved.

13 Sep 2024

Obesity medication liraglutide is safe and effective in children aged 6 to <12 years

Liraglutide treatment significantly lowers BMI in obese children aged 6 to <12, but gastrointestinal side effects prompt the need for additional studies.

13 Sep 2024

Salt can boost antitumor responses of T cells

Elevated sodium levels in tumors boost T-cell metabolic fitness and cytotoxicity, revealing potential avenues for improving cancer therapies.

13 Sep 2024

Novel drug delivery system aims to prevent hearing loss from cisplatin chemotherapy

The chemotherapy drug cisplatin is a lifesaver for many adults and children diagnosed with cancer, but it often causes hearing loss, a side effect that can diminish quality of life following treatment.

13 Sep 2024

The potential benefits of aged black garlic on inflammation and prostate cancer

Researchers investigate the anti-inflammatory and anti-prostate cancer properties of aged black garlic extract.

13 Sep 2024

Melanoma incidence and mortality may eventually decrease among the entire Swedish population

Researchers assess the incidence of melanoma and mortality trends among younger patients.

13 Sep 2024

Cancer cases in the US continued to be underdiagnosed during the second year of the COVID-19 pandemic

Researchers examine how the COVID-19 pandemic affected cancer diagnosis rates between 2021 and 2020.

13 Sep 2024

Researchers find no evidence of monkeypox infection in pets, despite presence of viral DNA

Study found that MPXV DNA on pets in mpox-affected households was likely due to human contamination, not true infection, as no live virus or antibodies were detected.

12 Sep 2024

New gene variants linked to early menopause and cancer risk identified

Study reveals nine gene variants linked to ovarian aging and cancer risk, with implications for reproductive longevity and de novo mutation rates.

12 Sep 2024

No difference in health outcomes between 24-hour and 15-hour oxygen therapy

There were no differences in quality of life, symptoms, hospital admissions or mortality between a group of patients with pulmonary disease and low oxygen levels in the blood that received oxygen therapy at home for 24 hours a day, and a group that received the same therapy for 15 hours a day, according to a study from Lund University in Sweden.

12 Sep 2024

Cannabidiol shows promise in treating cognitive disorders

Research reviews the therapeutic potential of cannabidiol (CBD) in treating cognitive impairments, highlighting positive effects in some trials while emphasizing the need for more comprehensive studies.

12 Sep 2024

New discovery offers hope for overcoming CAR-T cell therapy resistance

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

12 Sep 2024

New vaccine candidate shows promise for protecting against Lassa fever

Researchers from Thomas Jefferson University and the University of Maryland Baltimore, in collaboration with the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) and the Geneva Foundation, have developed a promising new vaccine candidate that protects against Lassa fever.

12 Sep 2024

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Medical Science News

PPARs and PROTACs: A new strategy in cancer therapeutics

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

Breakthrough in understanding formaldehyde toxicity during development and aging

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

New blood test achieves 98% accuracy in diagnosing ALS

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

Study finds brain synchronization between humans and dogs during social interactions

Obesity medication liraglutide is safe and effective in children aged 6 to <12 years

Salt can boost antitumor responses of T cells

Novel drug delivery system aims to prevent hearing loss from cisplatin chemotherapy

The potential benefits of aged black garlic on inflammation and prostate cancer

Melanoma incidence and mortality may eventually decrease among the entire Swedish population

Cancer cases in the US continued to be underdiagnosed during the second year of the COVID-19 pandemic

Researchers find no evidence of monkeypox infection in pets, despite presence of viral DNA

New gene variants linked to early menopause and cancer risk identified

No difference in health outcomes between 24-hour and 15-hour oxygen therapy

Cannabidiol shows promise in treating cognitive disorders

New discovery offers hope for overcoming CAR-T cell therapy resistance

New vaccine candidate shows promise for protecting against Lassa fever

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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