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Targeting MYCN and MDM2 offers new hope for cancer therapy

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

29 Jan 2025

Climate change is pushing up rates of kidney disease and urological cancers

Climate change is increasing the risk of urological diseases, including cancer and kidney conditions, while urological healthcare itself contributes to environmental harm through high carbon emissions.

29 Jan 2025

Study reveals how glial cells respond to damage in neuron dendrites

Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste, and protect neurons from harm.

29 Jan 2025

Bioengineers create non-invasive way to control cells using temperature

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

29 Jan 2025

Is juicing good for your gut? Research shows surprising microbiome changes

Short-term fruit and vegetable juicing causes microbial shifts in the oral and gut microbiome, but these changes are mostly transient and return to baseline after 14 days.

29 Jan 2025

From gut health to metabolism: How sleep controls more than you think

Study reveals that sleep traits predict over 15% of body characteristics across 15 physiological systems, with visceral fat, cardiovascular health, and metabolism deeply intertwined with sleep patterns.

29 Jan 2025

Can an online lifestyle plan keep your brain sharp? Research says yes

"Maintain Your Brain" study shows how a tailored online program can improve cognition and lower dementia risk—discover how simple lifestyle changes could protect your brain as you age.

29 Jan 2025

New AI tool promises faster vaccine development by predicting T cell epitopes

An exciting collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging artificial intelligence (AI) to aid the development of T cell vaccine candidates.

29 Jan 2025

Researchers propose personalized probiotic therapies for inflammatory diseases

A new approach to treating inflammatory diseases through personalized probiotic therapies – also known as precision medicine – has been proposed by researchers at the University of Surrey.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

Leukocyte count predicts severity of COVID-19 symptoms in older women

Thanks to advances in treatment options, a COVID-19 diagnosis is no longer as scary as it once was, at least for most people.

29 Jan 2025

Potato consumption not linked to heart disease or hypertension

The analysis indicates that while potatoes don't raise heart disease risk, fried varieties may contribute to higher hypertension risk with regular consumption.

29 Jan 2025

Prolonged REM sleep latency linked to Alzheimer’s disease biomarkers

Research indicates longer REM latency is associated with higher Alzheimer's biomarkers, pointing to its potential as an early indicator of neurodegeneration.

29 Jan 2025

Swedish study reveals gaps in pain management for preterm infants

Research on pain in preterm infants shows frequent painful procedures and inadequate pain management, emphasizing the need for better assessment strategies.

29 Jan 2025

Discovery could contribute to the development of new drugs for transthyretin amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

New urine test shows promise for prostate cancer screening

Traditional approaches to prostate cancer screening involve blood tests, MRI, and biopsies.

28 Jan 2025

Researchers identify brain circuit to reduce anxiety without side effects

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.

28 Jan 2025

Scientists discover new skeletal tissue with potential for regenerative medicine

A global team of scientists has made a groundbreaking discovery of a new skeletal tissue known as "lipocartilage," offering immense potential for regenerative medicine and tissue engineering.

28 Jan 2025

New treatment identified for peripheral nerve sheath tumors

A multicenter collaboration led by the Bellvitge Biomedical Research Institute (IDIBELL) - Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) identified a potential new treatment for an aggressive sarcoma arising in the nerves.

28 Jan 2025

Study explores the effects of recent and lifetime cannabis use on brain function

A new study published today in JAMA Network Open explores the effects of both recent and lifetime cannabis use on brain function during cognitive tasks.

28 Jan 2025