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Study reveals menstrual cycle’s role in spreading mutant cells in breast tissue

A team of researchers at the VIB-KU Leuven Center for Cancer Biology, the Netherlands Cancer Institute and Oncode Institute and the University of Cambridge have discovered that a defensive mechanism connected to the menstrual cycle plays a role in spreading mutant cells within mammary tissue.

4 Sep 2024

Immune cells prevent the lungs' protective barrier from healing after viral infections

Investigators involved in a multicenter study co-led by Cedars-Sinai discovered a pathway by which immune cells prevent the lungs' protective barrier from healing after viral infections like COVID-19.

4 Sep 2024

Astrocytes reprogrammed to brain stem cells through methylation

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain.

4 Sep 2024

Brain scans reveal hidden clues to depression susceptibility

By repeatedly scanning the brains of a small group of patients for a year and a half, Weill Cornell Medicine researchers have identified a distinct pattern of neuronal interactions that appears to predispose some people to developing depression.

4 Sep 2024

Breakthrough antibiotic targets gum disease without harming microbiome

The ADA Forsyth Institute, a leading oral health research organization, and Flightpath Biosciences Inc. are excited to announce a groundbreaking discovery in the fight against severe gum disease and related systemic conditions.

4 Sep 2024

Study explores the effects of hyperosmotic stress on microglial cells

Microglia are the brain's immune cells known to play a vital role in maintaining neural function and responding to potential threats.

4 Sep 2024

Key insights into cardiac metabolism dysfunction in the elderly

A new editorial was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 16 on August 19, 2024, entitled, "Cardiac metabolism in the elderly: effects and consequences."

4 Sep 2024

OSER1 protein found to have great influence on longevity

It turns out that a particular gene has a great influence on longevity, a new study from the University of Copenhagen concludes. This may pave the way for new treatment.

4 Sep 2024

Novel intermediate form of serotonin receptor identified as therapeutic target for psychiatric disorders

Misha Kudryshev's lab at the Max Delbrück Center has identified a molecular intermediate of a serotonin receptor that is involved in diseases such as depression and schizophrenia.

4 Sep 2024

Magnetic nanoparticles enhance safe thawing of cryopreserved tissues

Every day, people die waiting for an organ transplant. Time is at a premium, not just for those awaiting organs, but also for the organs themselves, which can deteriorate rapidly during transportation.

4 Sep 2024

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

Today, the Allen Institute for Cell Science and New York Stem Cell Foundation (NYSCF) announced a pioneering collaboration to address this critical issue, combining two cutting-edge technologies to create more inclusive cellular models for studying disease.

4 Sep 2024

New immunotherapy approach shows promise for minimizing spinal cord injury damage

WashU Medicine researchers have designed, in mice, an approach to minimizing the damage from a spinal cord injury through the use of engineered immune cells.

4 Sep 2024

Sports concussions may not be related to long-term cognitive risks for non-professional athletes

Sports-related concussions (SRC) may not be associated with long-term cognitive risks for non-professional athletes, a study led by a UNSW medical researcher suggests.

4 Sep 2024

Lifestyle interventions in patients after colorectal cancer treatment

A recent RCT reveals the HEAL ABC intervention is feasible for 87% of colorectal cancer survivors, supporting healthy lifestyle changes and improved well-being.

4 Sep 2024

Avadel Pharmaceuticals announces publication of RESTORE data highlighting challenges with twice-nightly oxybates and strong patient preference for once-nightly LUMRYZ™ dosing (sodium oxybate) extended-release oral suspension (CIII)

Avadel Pharmaceuticals plc, a biopharmaceutical company focused on transforming medicines to transform lives, today announced the publication of final data from the RESTORE open-label/switch study, demonstrating that people with narcolepsy prefer once-at-bedtime LUMRYZ versus a twice-nightly immediate-release oxybate treatment option.

From Avadel Pharmaceuticals 4 Sep 2024

Understanding the impact of BMI on colorectal cancer risk in Asia

Researchers report that body mass index values in Asians population may predict the risk of developing colorectal cancer.

4 Sep 2024

Does air pollution drive dementia?

Chronic air pollution exposure is a key factor in dementia development, with pollutants like PM2.5 and NO2 linked to cognitive decline and neurodegeneration.

4 Sep 2024

Sleep too much or too little? Your cognition pays the price

Findings indicate that both insufficient and excessive sleep are linked to higher mild cognitive impairment risk, underscoring the importance of balanced sleep.

4 Sep 2024

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

Researchers reveal how aging and psychiatric disorders converge at the cellular level in the orbitofrontal cortex, identifying key gene expression changes that could lead to new therapies.

4 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024