Molecular & Structural Biology

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Scientists discover critical factor in bone remodeling process

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

21 Jan 2025

NIH provides $14 million to support human genome research diversification

Washington University School of Medicine in St. Louis has received two large grants renewing funding for the Human Pangenome Reference Sequencing Project.

21 Jan 2025

Breakthrough study maps critical structure of Nipah virus polymerase

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has caused outbreaks in humans almost every year since it was identified in 1999.

20 Jan 2025

New approach combines two methods to study disordered proteins

Researchers of Mainz University and EMBL Hamburg present a new approach to determine the form of disordered proteins by using two different methods simultaneously in a single sample.

20 Jan 2025

Manuka vs. Ohia Lehua honey: Study reveals key antioxidant differences and health benefits

Study compares the antioxidant properties of Manuka honey (MH) and Ohia Lehua honey (OLH), revealing that MH contains ten times more phenolic content, while OLH demonstrates superior in vivo antioxidant activity by reducing oxidative stress and enhancing antioxidant capacity.

19 Jan 2025

Granzyme K+ CD8+ T-cells identified as key drivers of recurrent airway inflammation

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases.

17 Jan 2025

Immune cells orchestrate glucagon production during fasting

When we think about the immune system, we usually associate it with fighting infections. However, a study published in Science by the Champalimaud Foundation reveals a surprising new role.

17 Jan 2025

Sapio Sciences introduces new tools for chemistry, molecular biology, GMP workflows, and immunogenicity

Sapio Sciences, the science-aware™ lab informatics platform, today announced the launch of Release 24.12, introducing new tools for chemistry, molecular biology, GMP workflows, and immunogenicity.

15 Jan 2025

Scientists discover how specific protein regions contribute to breast cancer

Researchers at Case Western Reserve University School of Medicine have discovered how specific protein regions contribute to breast cancer.

15 Jan 2025

Pancreatic cancer insights: How pORG classifications predict survival and guide treatment

Researchers identify distinct molecular and immune profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma.

15 Jan 2025

World’s largest proteomics study launched by UK Biobank

UK Biobank has today announced the launch of the world's most comprehensive study of the proteins circulating in our bodies, which will transform the study of diseases and their treatments.

9 Jan 2025

Study unveils novel pathway triggering immune response to DNA damage

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged.

6 Jan 2025

RNA on leaf surfaces plays role in shaping plant microbiomes

Biologists at Indiana University Bloomington have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules.

3 Jan 2025

New protein offers hope for heart regeneration

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish.

2 Jan 2025

Novel tool holds great promise for studying mitochondrial calcium signaling

Mitochondrial calcium signaling is crucial for energy metabolism and calcium homeostasis, but monitoring it accurately is challenging due to pH fluctuations.

27 Dec 2024

The "Goldilocks" zone: A key to cellular adaptability and resilience

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life: DNA and the element magnesium.

24 Dec 2024

New SIMPL2 platform revolutionizes the study of protein-protein interactions

A team led by researchers at the University of Toronto has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy.

23 Dec 2024

Linker histones found to regulate DNA transcription in apple cells

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's genetic code expresses itself.

23 Dec 2024

Generating mutated proteins through adversarial attacks on the AlphaFold2 model

Announcing a new publication for Acta Materia Medica journal. Proteins are essential macromolecules that perform functions according to their conformational dynamics.

21 Dec 2024

New synthetic biology breakthrough improves genetic circuit integration

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

20 Dec 2024