Molecular & Structural Biology

RSS

Discovery of cellular process could impact the understanding of cancer and aging

Researchers at UC Merced used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging.

3 Sep 2024

Gut bacteria pathways directly linked to insomnia risk identified

Study uncovers a causal link between specific gut microbiome metabolic pathways and insomnia, highlighting potential therapeutic targets for improving sleep quality.

3 Sep 2024

RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

The Mass General Brigham Gene and Cell Therapy Institute (GCTI) today announced it has launched the RNA Therapeutics Core, a first-of-its-kind, state-of-the-art facility and resource to advance the use of RNA technologies within and beyond the Mass General Brigham research ecosystem.

3 Sep 2024

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

Advances in tissue engineering and 3D bioprinting have revolutionized the development of physiologically relevant 3D in vitro cancer models, offering a closer representation of the tumor microenvironment (TME) and enabling high-throughput drug screening.

From Carcinotech 30 Aug 2024

AI unveils secrets of protein stability

Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI. The research team used AlphaFold2 to explore how mutations affect protein stability-; a crucial factor in ensuring proteins function correctly and do not cause diseases like Alzheimer's.

29 Aug 2024

New photoacoustic probes could revolutionize brain activity imaging

To understand the brain better, we need new methods to observe its activity.

28 Aug 2024

CDCA7 identified as key player in hemimethylation sensing

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked.

28 Aug 2024

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Researchers have identified an endogenous insulin antagonist, INS-7, in Caenorhabditis elegans that modulates fat loss by inhibiting a gut-to-brain signaling pathway involving the neuropeptide FLP-7.

27 Aug 2024

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Synthetic immunology, an innovative field of research which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the "Perspectives" section of the journal "Nature Nanotechnology". Herein, Heidelberg researchers Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht, and Prof. Dr. Oliver T. Fackler describe a so-called bottom-up approach that uses the toolbox of nanotechnology and synthetic biology to construct systems from molecular building blocks and specifically equip them with immune functions.

27 Aug 2024

Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

The study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of atherosclerosis, a disease characterized by lipid accumulation and plaque formation in arteries.

27 Aug 2024

Computational tools reveal 3D structures of viral proteins

These rapid shifts mean that researchers are still trying to understand a multitude of viral proteins and precisely how they increase viruses' infecting abilities-; knowledge that could be crucial for developing new or better virus-fighting treatments.

27 Aug 2024

Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity

Austocystin D, a natural compound produced by fungi, has been recognized for its cytotoxic effects and anticancer activity in various cell types. It exhibits potent activity even in cells that express proteins associated with multidrug resistance, attracting significant global research interest.

27 Aug 2024

Molecular & Structural Biology

Discovery of cellular process could impact the understanding of cancer and aging

Gut bacteria pathways directly linked to insomnia risk identified

RNA Therapeutics Core launches at Mass General Brigham to boost circular RNA research

Carcinotech publishes research on patient-derived 3D-printed tumors as a breakthrough tool for drug development

AI unveils secrets of protein stability

New photoacoustic probes could revolutionize brain activity imaging

CDCA7 identified as key player in hemimethylation sensing

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

Computational tools reveal 3D structures of viral proteins

Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity

How diet shapes gut microbiota and affects brain function

Gut microbe metabolite found to modulate heart disease risk through β2-adrenergic receptors

GPePV neurons identified as key players in controlling cocaine addiction behaviors

Human gut microbiome: A source of new antibiotic peptides

New technique enhances study of complex biological processes at the molecular level

AI-powered Surreal-GAN identifies diverse brain aging patterns

Researchers reveal impact of genetic ancestry on breast cancer risk and cell diversity

New Springer textbook provides a comprehensive overview of aging science

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News