Molecular & Structural Biology

RSS

U-M scientists develop new tool to better understand neuronal signaling

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons.

23 Apr 2024

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.

22 Apr 2024

B Medical Systems’ Solar Direct Vaccine Refrigerator and Ice-Pack Freezer, the TCW40SDD, Receives the ACT Label

B Medical Systems is proud to announce that two of its products have received the prestigious ACT label from My Green Lab.

From B Medical Systems S.à r.l 18 Apr 2024

Study reveals structural dynamics of key hearing receptor

Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republic of Korea) has collaborated with Professor Kwang Pyo Kim's group from the Department of Applied Chemistry at Kyung Hee University (KHU, ROK), Professor Vsevolod Katritch's team from the University of Southern California (USC, USA), and Professor Carol V. Robinson from the University of Oxford (UK) to uncover the mysteries surrounding a specific receptor protein associated with hearing.

15 Apr 2024

Ketamine's rapid impact on depression linked to immune system pathways

Study reveals ketamine's potent anti-inflammatory effects on neurological disorders, showing promise for treating major depressive disorder through modulation of neuroimmune pathways.

15 Apr 2024

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl.

13 Apr 2024

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Cells contain various specialized structures - such as the nucleus, mitochondria or peroxisomes - known as "organelles''.

12 Apr 2024

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Sex differences are widespread across human development, physiological processes, and diseases, making it important to characterize the impact of sex differences in these areas.

12 Apr 2024

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

...

From Metrion Biosciences Limited 11 Apr 2024

Baylor study reveals role of newly inherited DNA variants in recessive diseases

You have your mother's eyes and your father's smile, but genetics is much more than just what's on the surface.

10 Apr 2024

Novel signaling pathway identified in lysosome damage response

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm.

8 Apr 2024

Discovery of a fundamental biological mechanism opens path for novel therapies

The lab of Yongchao C. Ma, PhD, at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered a fundamental biological mechanism that could lead to new treatments for neurological diseases, such as spinal muscular atrophy (SMA) and autism, as well as different cancers.

4 Apr 2024

Computational tools predict protein-RNA interactions

Researchers from Aarhus University and the Italian Institute of Technology have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes.

3 Apr 2024

Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

2 Apr 2024

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Researchers in Brazil have used an innovative technique in molecular biology to identify targets for candidate vaccines against Schistosoma mansoni, the parasite that causes schistosomiasis.

2 Apr 2024

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Study demonstrated that selectively reducing myeloid-biased hematopoietic stem cells (my-HSCs) in aged mice rejuvenated the immune system, enhanced lymphopoiesis, reduced inflammation, and improved responses to viral infection, highlighting a potential strategy for countering age-related immune decline.

31 Mar 2024

New insights into gas vesicle clustering in bacteria open doors for biomedical applications

Gas vesicles are hollow structures made of protein found in the cells of certain microorganisms, and researchers at Rice University believe they can be programmed for use in biomedical applications.

29 Mar 2024

Study reveals protein structure similarities in Alzheimer's and Down syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

29 Mar 2024

Rapid miRNA detection with one-pot isothermal rolling circle amplification

This study is led by Professor Jue Ruan (Chinese Academy of Agricultural Sciences, Shenzhen, China). The authors developed a one-pot isothermal detection method based on rolling circle amplification (RCA) for rapid and specific detection of miRNAs and short RNA fragments.

29 Mar 2024

Research offers first insights into the mechanism behind synaptic development

The first analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders.

28 Mar 2024

Molecular & Structural Biology

U-M scientists develop new tool to better understand neuronal signaling

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

B Medical Systems’ Solar Direct Vaccine Refrigerator and Ice-Pack Freezer, the TCW40SDD, Receives the ACT Label

Study reveals structural dynamics of key hearing receptor

Ketamine's rapid impact on depression linked to immune system pathways

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Visualizing centriole genesis with microscopy and kinematic reconstruction techniques

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Metrion Biosciences enhances High Throughput Screening services with access to Enamine compound libraries

Baylor study reveals role of newly inherited DNA variants in recessive diseases

Novel signaling pathway identified in lysosome damage response

Discovery of a fundamental biological mechanism opens path for novel therapies

Computational tools predict protein-RNA interactions

Atomic-level structural models of enzymes provide disease insights

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

New insights into gas vesicle clustering in bacteria open doors for biomedical applications

Study reveals protein structure similarities in Alzheimer's and Down syndrome

Rapid miRNA detection with one-pot isothermal rolling circle amplification

Research offers first insights into the mechanism behind synaptic development

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News