Molecular & Structural Biology

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Researchers decode 3D architecture of SARS-CoV-2 main protease

Teams around the world are working hard to develop active substances against SARS-CoV-2. The structural analysis of functional proteins of the virus is very helpful for this goal. The function of a protein is closely related to its 3D architecture.

21 Mar 2020

Novel MRI contrast agent for early detection of brain metastases

A group of researchers led by Leif Schroeder from the Leibniz-Forschungsinstitut fuer Molekulare Pharmakologie have found a way to detect metastases in certain types of cancer in the brain at an early stage, using only minimal amounts of contrast agent.

19 Mar 2020

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

When parents eat low-protein or high-fat diets it can lead to metabolic disorders in their adult offspring. Now, an international team led by researchers at the RIKEN Cluster for Pioneering Research have identified a key player and the molecular events underlying this phenomenon in mice.

19 Mar 2020

EHD2 protein plays a key role in fat metabolism

Many foods - whether it's the mozzarella on your favorite pizza, the olive oil in salad dressing or hollandaise sauce during asparagus season - contain lots of fat. The fatty acids in these foods are among the essential nutrients that people need to survive.

17 Mar 2020

Micro-CT scanning of 'Little Foot' skull reveals how human ancestor lived 3 million years ago

High-resolution micro-CT scanning of the skull of the fossil specimen known as "Little Foot" has revealed some aspects of how this Australopithecus species used to live more than 3 million years ago.

17 Mar 2020

New type of artificial binding proteins for blocking sugar structures on cell surfaces

The laboratory directed by Arne Skerra, Professor of Biological Chemistry, has its focus on designing artificial binding proteins for therapeutic applications.

17 Mar 2020

Cannabinoid 1 receptor expression displays sexually dimorphic pattern in the mouse brain

A major challenge in neuroscience lies in understanding how molecular and circuit differences in the brain synergistically contribute to sex differences in behavioral phenotypes. Sex differences in the brain may arise from the identity, distribution and relative abundance of cell types.

17 Mar 2020

Scientists use artificial intelligence to create new proteins unseen in nature

Researchers have presented a artificial intelligence method for developing new proteins that have never been seen in nature.

17 Mar 2020

Scientists engineer silkworms to produce different variants of adhesion molecules

Silkworms are useful for more than just making strong and absorbent strings of silky thread for the textiles industry.

16 Mar 2020

Two brain-signaling molecules control anemonefish fathering and aggression

Two brain-signaling molecules control how anemonefish dads care for their young and respond to nest intruders, researchers report in a new study.

16 Mar 2020

Researchers show possibility of blending two incompatible components in one nanofiber

Russian researchers from the Federal Research Clinical Center of Physical-Chemical Medicine, the Moscow Institute of Physics and Technology, and Lomonosov Moscow State University showed the possibility of blending two incompatible components -- a protein and a polymer -- in one electrospun fiber.

16 Mar 2020

Study provides new insights into brain evolution

Their researches on the lamprey brain has enabled researchers at Karolinska Institutet in Sweden to push the birth of the cortex back in time by some 300 million years to over 500 million years ago, providing new insights into brain evolution.

16 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

SPRK1 enzyme plays role in reorganizing the paternal genome during fertilization

A sperm enters an egg, an embryo develops and eventually a baby is born. But back up a second -- how does the mother's half-genome actually merge with the father's half-genome to form one new human genome?

13 Mar 2020

Researchers reveal nerve circuitry regulating worms' response to changing temperatures

Nagoya University researchers and colleagues have revealed the nerve circuitry regulating the response of a tiny soil worm to changing temperatures.

13 Mar 2020

Researchers uncover possible pitfalls of common hormone analysis in animal hair

Similar to humans, wild animals' reaction to disturbance is accompanied by releasing hormones, such as cortisol.

12 Mar 2020

New biochemical mechanism in cells is crucial component of anti-aging program

Aging is an inevitable part of life, yet some species are aging very differently than others, even than very similar ones.

11 Mar 2020

Researchers probe how specific genes can impact early brain development

When brains begin developing, there are a lot of moving parts -- and when mutations happen in early neurodevelopment, it can lead to disorders like macrocephaly and autism.

11 Mar 2020

Retino-cortical mapping shown to be prime determinant in the topography of cortical organization

Researchers have explained how visual cortexes develop uniquely across the brains of different mammalian species.

11 Mar 2020

Study shows JNK protein as a stress sensor in synapses

New study from Eleanor Coffey's lab at Turku Bioscience Centre in Finland identifies that the JNK protein triggers nerve cells to withdraw their synapses when stressed.

11 Mar 2020

Molecular & Structural Biology

Researchers decode 3D architecture of SARS-CoV-2 main protease

Novel MRI contrast agent for early detection of brain metastases

Researchers uncover molecular events underlying paternal diet-induced metabolic disorders in children

EHD2 protein plays a key role in fat metabolism

Micro-CT scanning of 'Little Foot' skull reveals how human ancestor lived 3 million years ago

New type of artificial binding proteins for blocking sugar structures on cell surfaces

Cannabinoid 1 receptor expression displays sexually dimorphic pattern in the mouse brain

Scientists use artificial intelligence to create new proteins unseen in nature

Scientists engineer silkworms to produce different variants of adhesion molecules

Two brain-signaling molecules control anemonefish fathering and aggression

Researchers show possibility of blending two incompatible components in one nanofiber

Study provides new insights into brain evolution

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

SPRK1 enzyme plays role in reorganizing the paternal genome during fertilization

Researchers reveal nerve circuitry regulating worms' response to changing temperatures

Researchers uncover possible pitfalls of common hormone analysis in animal hair

New biochemical mechanism in cells is crucial component of anti-aging program

Researchers probe how specific genes can impact early brain development

Retino-cortical mapping shown to be prime determinant in the topography of cortical organization

Study shows JNK protein as a stress sensor in synapses

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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