Molecular & Structural Biology

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Molecular pathways underlying myopia open new ways for drug development

Myopia (nearsightedness) and hyperopia (farsightedness) develop through different molecular pathways, according to a new study publishing October 9 in the open-access journal PLOS Biology by Andrei Tkatchenko of Columbia University and colleagues.

10 Oct 2018

Honey Analyses: Using NMR to Reduce Fraud

This interview with CEO of Sweetwater Labs, Jim Gawenis, explores the increasing importance of NMR in the detection of honey fraud.

From Bruker BioSpin - NMR, EPR and Imaging 10 Oct 2018

Louisiana amphibian shows resistance to skin disease caused by fungus

Amphibian populations around the world are declining due to a skin disease caused by fungus. However, an amphibian commonly found in Louisiana, the three-toed amphiuma, has shown a resistance to the fungus, in a new study led by researchers at LSU, Southeastern Louisiana University, Duquesne University and the University of Washington.

10 Oct 2018

Study shows role of protein in tuning synaptic transmission critical for cognition

Our cognitive abilities come down to how well the connections, or synapses, between our brain cells transmit signals.

10 Oct 2018

Brown researchers uncover new clues about ALS progression

Brown University researchers have uncovered new clues about the progression of Amyotrophic Lateral Sclerosis (ALS), a surprisingly common disease that causes the death of motor neurons that control voluntary muscles such as those involved in walking, talking, chewing or breathing.

10 Oct 2018

UTSA acquires state-of-the-art microscope to write commands directly into neurons

It's about the size of a dinner table; yet, one day may influence conversations held around the kitchen table. This is what excites researchers at the University of Texas at San Antonio as they anticipate the arrival of a state-of-the-art microscope.

10 Oct 2018

'Molecular baskets' show promise to trap deadly nerve agents and toxic compounds

Researchers have developed designer molecules that may one day be able to seek out and trap deadly nerve agents and other toxic compounds in the environment - and possibly in humans.

10 Oct 2018

Scientists identify new biomarker for Alzheimer's disease of sporadic origin

The objective of the research, undertaken in the laboratories of the IBPM, is to develop a model for studying Alzheimer's disease of sporadic origin, in other words, not due to a hereditary genetic mutation.

10 Oct 2018

Scientists discover pheromone-sensing gene that predates land-dwelling vertebrates

Scientists at Tokyo Institute of Technology have discovered a gene that appears to play a vital role in pheromone sensing. The gene is conserved across fish and mammals and over 400 million years of vertebrate evolution, indicating that the pheromone sensing system is much more ancient than previously believed.

10 Oct 2018

Researchers create open access database on healthy immunity

Researchers have created a freely available database of healthy human immunity that can serve as an instant comparison group in immune system studies.

9 Oct 2018

Massively parallel single-nucleus RNA sequencing reveals insights into heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

9 Oct 2018

New genome editing tool used to heal genetic disease

Parents of newborns may be familiar with the metabolic disorder phenylketonuria: in Switzerland, all newborn babies are screened for this genetic disease.

8 Oct 2018

New epigenetic screening method could improve cancer detection

Researchers have found a better way to determine the epigenetic code of DNA for the identification of disease, using enzymes instead of bisulphite.

8 Oct 2018

Researchers use CRISPR-Cas9 to prevent congenital disease in utero

Researchers have successfully used prenatal gene editing (CRISPR-Cas9) to prevent a fatal metabolic disorder in an animal model.

8 Oct 2018

Yale researchers discover how deadly biofilms develop

By severely curtailing the effects of antibiotics, the formation of organized communities of bacterial cells known as biofilms can be deadly during surgeries and in urinary tract infections. Yale researchers have just come a lot closer to understanding how these biofilms develop, and potentially how to stop them.

5 Oct 2018

Scientists call for microbiota vault of healthy bacteria

A team of researchers are gathering bacteria from across the world to create a microbiota vault containing healthy bacteria from the human gut and skin.

5 Oct 2018

New method for studying the cell nucleus could improve disease detection

Researchers at New York University have found a way to measure the physical properties of the nucleus and its constituents in live human cells.

5 Oct 2018

A Single Platform to Sequence All Monoclonal Antibody Proteins

Having a single platform to sequence all monoclonal antibody proteins provides researchers with key information for research, development and drug discovery

From Rapid Novor Inc 3 Oct 2018

Molecule research reveals potential drug target for treating stroke patients

In an extension of research published a month ago in Nature Methods, a novel hybrid approach performed by researchers from Clemson University's department of physics and astronomy and Stony Brook University has revealed a 3-D structure of a protein fragment that could serve as a drug target in treating stroke patients.

3 Oct 2018

Researchers for the first time differentiate human inner ear cells in laboratory

Researchers from the University of Bern and Bern University Hospital have managed for the first time to differentiate human inner ear cells in a laboratory from somatic progenitors and to investigate their origin.

3 Oct 2018