Molecular & Structural Biology

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McGill scientists invent new technique for measuring enzyme inhibition

Researchers at McGill University have invented a new technique for measuring how quickly drugs interact with their molecular targets. The discovery provides scientists with a new way to investigate the effectiveness of drug candidates that might otherwise have been overlooked.

2 Mar 2018

CRISPR enzyme can also cleave RNA, finds study

Researchers have discovered that the Cas-9 enzyme used in CRISPR gene editing can also cleave complimentary messenger RNA, in addition to DNA.

2 Mar 2018

MIPT biophysicists study structure and interaction of nanofibrous scaffold with cardiac cells

Biophysicists from MIPT have studied the structure of a nanofibrous scaffold, as well as its interaction with rat cardiac cells.

2 Mar 2018

Researchers develop method to make adult cardiomyocytes divide and repair damaged hearts

Some organisms have a remarkable capacity for regenerating tissue. If a fish or salamander suffers heart damage, for instance, their cells are able to divide and successfully repair the injured organ. Imagine if you could do the same.

2 Mar 2018

Tradeshow Talks with CDS Analytical

We spoke to Terry from CDS Analytical at Pittcon 2018.

1 Mar 2018

Pesticides are accumulated in bodies with high fat content, FEFU scientists say

Pesticides are accumulated in bodies with high fat content. This conclusion was made by the scientists from the Far Eastern Federal University that have been studying seabirds and marine mammals of the Sea of Okhotsk and the Bering Sea for several years.

1 Mar 2018

UNIGE researchers discover why premature cell division promotes tumor formation

The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division.

28 Feb 2018

Tradeshow Talks with Labconco

We talked to product manager Kelly from Labconco at Pittcon 2018.

From Labconco 28 Feb 2018

Quiescent cells also acquire particular type of mutation, research shows

For almost a hundred years, geneticists have believed that the more a cell divides the more mutations it acquires. However, research by scientists at the Institut Pasteur shows that quiescent cells, which do not divide, also acquire a particular type of mutation - deletions (mutations through loss of nucleobases).

27 Feb 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

27 Feb 2018

Researchers develop new tool that provides 3D view of metabolic processes

An international team of researchers has developed a computational resource that provides a 3D view of genes, proteins and metabolites involved in human metabolism.

27 Feb 2018

Researchers discover key inner control mechanism of cell's 'smart glue'

Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its function.

26 Feb 2018

Research reveals anti-cancer effects of natural extract from Daffodils

A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.

26 Feb 2018

New discovery could help understand and treat glaucoma

Researchers have discovered two distinct groups of short molecules that regulate gene expression in the eyes of people with two different forms of glaucoma.

26 Feb 2018

Scientists reveal new insights into mechanism of gene regulation by 'magic spot'

Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the "magic spot"--a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

24 Feb 2018

Study unravels novel cellular and molecular pathway that regulates innate, adaptive immunity

Researchers at Brigham and Women's Hospital have discovered a new cellular and molecular pathway that regulates CD4+ T cell response--a finding that may lead to new ways to treat diseases that result from alterations in these cells.

24 Feb 2018

Researchers discover mechanism that could open doors to new treatments for celiac disease

Celiac disease is an autoimmune disorder that affects by some estimates nearly 1 in 100 people. Celiac disease symptoms are triggered by gluten, a protein found in wheat and related plants, but gluten doesn't act alone to cause the digestive symptoms that patients suffer.

23 Feb 2018

New study identifies mechanisms to lengthen egg viability in worms

Women have been told for years that if they don't have children before their mid-30s, they may not be able to. But a new study from Princeton University's Coleen Murphy has identified a drug that extends egg viability in worms, even when taken midway through the fertile window, which could theoretically extend women's fertility by three to six years.

23 Feb 2018

Research consortium develops first 3D computer model of metabolic processes

An international research consortium developed, with significant involvement of Luxembourg Centre for Systems Biomedicine scientists, the first computer model to include 3D in the representation of human metabolic processes.

22 Feb 2018