Molecular & Structural Biology

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Protein could be key to blocking the most common bacterial cause of food poisoning

Washington State University researchers have discovered a protein that could be key to blocking the most common bacterial cause of human food poisoning in the United States.

30 Mar 2021

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

A study conducted at the University of Campinas in the state of São Paulo, Brazil, shows that compounds produced by gut microbiota (bacteria and other microorganisms) during fermentation of insoluble fiber from dietary plant matter do not affect the ability of the novel coronavirus SARS-CoV-2 to enter and replicate in cells lining the intestines.

30 Mar 2021

Researchers create novel light sensor from algae's rhodopsins

The unicellular green alga Chlamydomonas reinhardtii has already given research a massive boost: One of its light sensors, channelrhodopsin-2, founded the success of optogenetics about 20 years ago.

30 Mar 2021

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) -- the virus that causes cold sores, as well as genital herpes -- activate gene expression in neurons.

29 Mar 2021

Using molecular ‘cookie cutters’ to isolate first ever COVID-19 encounter complex

University of Birmingham researchers are working to isolate and extract the COVID-19 encounter complex in a form that is stable enough for identification of target sites for future anti-viral drugs.

27 Mar 2021

Researchers identify neural circuit involved in reciprocally regulating weight gain and depression

Research has found that obesity and mental disorders such as depression and anxiety seem to often go hand in hand.

26 Mar 2021

Researchers develop first human model for studying the neuronal pathology of Leigh syndrome

Leigh syndrome is the most severe mitochondrial disease in children. It causes severe muscle weakness, movement defects, and intellectual disabilities.

26 Mar 2021

Research sheds light on a new neuroprotective mechanism to control damage following brain injury

When the brain suffers injury or infection, glial cells surrounding the affected site act to preserve the brain's sensitive nerve cells and prevent excessive damage.

26 Mar 2021

Salk joins a long list of recipients included in The Conrad Prebys Foundation’s inaugural grant cycle

Salk Professor Thomas Albright has been awarded $1 million and Assistant Professor Edward Stites awarded $500,000 by The Conrad Prebys Foundation as part of its inaugural round of grants.

26 Mar 2021

Scientists reveal molecular mechanisms involved in eliminating unwanted body cells

Scientists at the Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have revealed molecular mechanisms involved in eliminating unwanted cells in the body.

26 Mar 2021

Scientists describe the mechanisms that regulate embryonic stem cells

Scientists at the Proteomics Core Unit of the Spanish National Cancer Research Centre (CNIO), headed by Javier Muñoz, have described the mechanisms, unknown to date, involved in maintaining embryonic stem cells in the best possible state for their use in regenerative medicine.

26 Mar 2021

Researchers characterize a potential therapeutic target to weaken COVID-19

When invaded by a virus, our body cells launch an alert to neighboring cells to increase their antiviral defenses to prevent the infection from spreading.

24 Mar 2021

Researchers produce a detailed molecular atlas of lung development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

24 Mar 2021

Researchers discover a gene mutation linked to schizophrenia

Researchers at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, have identified a gene mutation that could result in schizophrenia, a chronic brain disorder that affects nearly one percent of the world’s population. T

24 Mar 2021

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

All viruses mutate as they make copies of themselves to spread and thrive. SARS-CoV-2, the virus the causes COVID-19, is proving to be no different. There are currently more than 4,000 variants of COVID-19, which has already killed more than 2.7 million people worldwide during the pandemic.

23 Mar 2021

Researchers develop new method for measuring immunity to coronavirus

Igor Stagljar made his career building molecular tools to combat cancer. But when the pandemic hit last March, he aimed his expertise at a new adversary, SARS-CoV-2.

22 Mar 2021

First model of early human embryo generated from skin cells

In a discovery that will revolutionise research into the causes of early miscarriage, infertility and the study of early human development - an international team of scientists led by Monash University in Melbourne, Australia has generated a model of a human embryo from skin cells.

22 Mar 2021

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

Most drugs operate via the membranes that surround the body's cells. A study by researchers at Karolinska Institutet in Sweden has now mapped the structure and mechanism of MGST2, a membrane enzyme that, amongst other things, plays a part in chronic inflammation and cancer.

20 Mar 2021

Researchers produce extremely conductive hydrogel for medical applications

Due to their tissue-like mechanical properties, hydrogels are being increasingly used for biomedical applications; a well-known example are soft contact lenses.

20 Mar 2021

Study reveals biomarkers for the prognosis of gastric adenocarcinoma

Low plasma levels of protein TGFB1 and polymorphisms in gene TGFB1 act as biomarkers for the prognosis of gastric adenocarcinoma, according to a study led by the University Complutense of Madrid.

18 Mar 2021

Molecular & Structural Biology

Protein could be key to blocking the most common bacterial cause of food poisoning

Microbiota-derived molecules do not change the entry or replication of SARS-CoV-2 in intestinal cells

Researchers create novel light sensor from algae's rhodopsins

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Using molecular ‘cookie cutters’ to isolate first ever COVID-19 encounter complex

Researchers identify neural circuit involved in reciprocally regulating weight gain and depression

Researchers develop first human model for studying the neuronal pathology of Leigh syndrome

Research sheds light on a new neuroprotective mechanism to control damage following brain injury

Salk joins a long list of recipients included in The Conrad Prebys Foundation’s inaugural grant cycle

Scientists reveal molecular mechanisms involved in eliminating unwanted body cells

Scientists describe the mechanisms that regulate embryonic stem cells

Researchers characterize a potential therapeutic target to weaken COVID-19

Researchers produce a detailed molecular atlas of lung development

Researchers discover a gene mutation linked to schizophrenia

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

Researchers develop new method for measuring immunity to coronavirus

First model of early human embryo generated from skin cells

Study maps structure and mechanism of a membrane enzyme that plays role in inflammation, cancer

Researchers produce extremely conductive hydrogel for medical applications

Study reveals biomarkers for the prognosis of gastric adenocarcinoma

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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