Molecular & Structural Biology

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Study reveals molecular machinery that regulates membrane association of Arf proteins

The small GTPases of the ADP-ribosylation factor (Arf) family are key initiators of various physiological processes including secretion, endocytosis, phagocytosis, and signal transduction. Arf family proteins function to mediate the recruitment of cytosolic effectors to specific subcellular compartments.

7 Jan 2021

A map of brainstem circuitry reveals which neurons control fine motor skills

Writing, driving a screw or throwing darts are only some of the activities that demand a high level of skill.

6 Jan 2021

Scientist receives $1.37 million grant to advance metabolomics data

The National Institutes of Health (NIH) has awarded University of Massachusetts Amherst biostatistician Raji Balasubramanian a four-year, $1.37 million grant to advance the analysis of data from metabolomics research.

5 Jan 2021

Groundbreaking research project shows how brain health can traverse generations

Your father's exercise routine may have made you smarter according to EU-funded researchers studying how lifestyle choices affect brain function and memory. The findings could lead to new treatments for neurodegenerative conditions such as Alzheimer's disease.

5 Jan 2021

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a heteroduplex oligonucleotide (HDO) model, have demonstrated augmentation of ASO-based drugs by replacing the RNA strand with DNA.

5 Jan 2021

Researchers resolve mysteries about the function of key gene-silencing protein

A long-running debate over how an important gene-silencing protein identifies its targets has been resolved by researchers at Massachusetts General Hospital (MGH).

4 Jan 2021

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, making it a critical factor in regulating the anti-tumor immune response.

4 Jan 2021

Tissue healing after brain injury could spur tumor growth

The healing process that follows a brain injury could spur tumor growth when new cells generated to replace those lost to the injury are derailed by mutations, Toronto scientists have found.

4 Jan 2021

Researchers find mechanism underlying plasticity in adult brains

Developing brains constantly sprout new neuronal connections called synapses as they learn and remember. Important connections — the ones that are repeatedly introduced, such as how to avoid danger — are nurtured and reinforced, while connections deemed unnecessary are pruned away.

24 Dec 2020

Researchers discover how shattered chromosomes make cancer cells more aggressive

Cancer is one of the world's greatest health afflictions because, unlike some diseases, it is a moving target, constantly evolving to evade and resist treatment.

23 Dec 2020

Researchers identify new weapon to battle the rising tide of antibiotic-resistant bacteria

As scientists around the globe wage war against a novel, deadly virus, one University of Colorado Boulder lab is working on new weapons to battle a different microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unchecked, could kill an estimated 10 million people annually by 2050.

23 Dec 2020

Researcher discovers seven DNA fingerprints that define cancer risk

Lifestyle, or put another way 'bad habits', is one of the textbook explanations for why some people are at higher risk for cancer.

23 Dec 2020

Study uncovers a new paradigm for the role of the thymus in pregnancy

How the immune system adapts to pregnancy has puzzled researchers for decades. An international team of researchers, including scientists from IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – has now discovered that important changes in the thymus occur in order to prevent miscarriages and gestational diabetes.

23 Dec 2020

Molecular reporters produce fluorescence to expose the allies of tumor cells

Glioblastoma is the most common malignant brain tumor in adults. Roughly five in every 100,000 people develop this type of cancer each year.

23 Dec 2020

Scientists discover molecular defects associated with rare genetic disorder in children

Damien D'Amours and his team at the Ottawa Institute of Systems Biology needed three years to discover the molecular defects associated with the LIC Syndrome, a serious genetic disorder that affects young children and result in acute respiratory distress, immune deficiency and abnormal chromosomes.

22 Dec 2020

Molecular & Structural Biology

Study reveals molecular machinery that regulates membrane association of Arf proteins

A map of brainstem circuitry reveals which neurons control fine motor skills

Scientist receives $1.37 million grant to advance metabolomics data

Groundbreaking research project shows how brain health can traverse generations

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Researchers resolve mysteries about the function of key gene-silencing protein

Researchers discover protein crucial to T cell metabolism and anti-tumor immune response

Tissue healing after brain injury could spur tumor growth

Researchers find mechanism underlying plasticity in adult brains

Researchers discover how shattered chromosomes make cancer cells more aggressive

Researchers identify new weapon to battle the rising tide of antibiotic-resistant bacteria

Researcher discovers seven DNA fingerprints that define cancer risk

Study uncovers a new paradigm for the role of the thymus in pregnancy

Molecular reporters produce fluorescence to expose the allies of tumor cells

Scientists discover molecular defects associated with rare genetic disorder in children

Gene-regulating snippet of RNA may contribute to breast cancer metastasis

Study shows neuropeptide corazonin regulates the release of diapause hormone in silkworms

Study highlights the far-reaching effects of mutagenic compounds on human health

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

The weak spot of colon cancer stem cells

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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