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Novel compound treats addiction by eliminating drug-associated memories

Addicts, even those who have been abstinent for long periods of time, are often still vulnerable to their own memories of prior drug use.

23 Apr 2009

New drug restricts the growth of neuroblastoma

Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found a new drug that restricts the growth of neuroblastoma, a childhood brain cancer.

23 Apr 2009

Proof-of-concept for a DNA-based therapeutic vaccination against chronic hepatitis C

The first-proof-of-concept for a DNA-based therapeutic vaccination against chronic hepatitis C was announced today at EASL 2009, the Annual Meeting of the European Association for the Study of the Liver in Copenhagen, Denmark.

23 Apr 2009

Natural plant cannabinoids reduce multi-drug resistant infections

Cannabis Science, Inc., Dr. Robert Melamede, PhD., Director and Chief Science Officer, reported to the Board on the current state of research into the use of natural plant cannabinoids to reduce the spread of drug-resistant bacteria, including methicillin-resistant Staphyloccus aureus (MRSA), and the prospects for development of topical whole-cannabis treatments.

23 Apr 2009

Immune-boosting vaccine helps body fight cancer

Cancer Research UK-funded scientists have discovered that linking a molecule which initiates antibody production,to a 'saboteur' molecule, triggers the immune system to selectively destroy faulty cells. These findings published in Blood, could potentially be used to selectively destroy tumour cells while ignoring healthy cells.

23 Apr 2009

Watson Pharmaceuticals files ANDAs for generic Mucinex

Watson Pharmaceuticals, Inc. has confirmed that it has filed two Abbreviated New Drug Applications (ANDAs) with the U.S. Food and Drug Administration seeking approval to market its guaifenesin extended-release 600mg and 1200mg tablets and its dextromethorphan HBr/guaifenesin extended-release 30mg/600mg and 60mg/1200mg tablets prior to the expiration of patents owned by Reckitt Benckiser Inc.

22 Apr 2009

Scientists develop drugs to block skin cancer protein

Scientists have developed a potent group of potential drug candidates to treat skin cancer, according to a study in the Journal of Medicinal Chemistry today (Thursday).

22 Apr 2009

Lilly granted preliminary injunction to prevent launch of generic Raloxifene

Eli Lilly and Company has announced that the U.S. District Court for the Southern District of Indiana today issued a preliminary injunction to prevent the launch of a generic version of Lilly's medicine Evista (raloxifene HCl tablets) by Teva Pharmaceuticals until the Court renders its final ruling.

22 Apr 2009

New applications for proton pump inhibitors

In a new study, published in the May issue of Elsevier's Experimental Neurology (www.elsevier.com/locate/yexnr), scientists at the University of British Columbia have discovered that drugs commonly used to treat ulcers have significant neuroprotective properties, which appear to be enhanced when used in combination with ibuprofen, a widely used anti-inflammatory drug.

22 Apr 2009

Developmental drug protects cells from the damaging effects of radiation exposure

A drug currently under development at the University of Pittsburgh School of Medicine protects cells from the damaging effects of radiation exposure, a new study suggests.

22 Apr 2009

Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies

Peregrine Pharmaceuticals, Inc. has reported that two preclinical studies presented during the AACR 100th Annual Meeting 2009 provided further confirmation of the immunomodulatory mechanisms contributing to the anti-tumor activity of its phosphatidylserine (PS) targeting antibodies.

22 Apr 2009

Scientists suggest a mechanism for how lithium works in bipolar treatment

Lithium has been established for more than 50 years as one of the most effective treatments for bipolar mood disorder.

22 Apr 2009

Potential new drug blocks pathway of deadliest cancer

Scientists at Cancer Research Technology Ltd (CRT) will present exciting new findings showing that a potent and selective inhibitor of protein kinase D called CRT0066101, inhibits the growth of pancreatic tumours.

20 Apr 2009

Grapefruit juice boosts efficacy of drug rapamycin

In a small, early clinical trial, researchers at the University of Chicago Medical Center have found that combining eight ounces of grapefruit juice with the drug rapamycin can increase drug levels, allowing lower doses of the drug to be given.

20 Apr 2009

Safety of bird flu drug Tamiflu in children questioned

A prominent Japanese researcher reporting on the bird flu drug Tamiflu says the drug may not be safe for children.

20 Apr 2009

Vion Pharmaceuticals' NDA for Onrigin accepted for FDA review

Vion Pharmaceuticals, Inc. has announced that the New Drug Application (NDA) for its lead oncology therapeutic Onrigin (laromustine) Injection has been accepted for review by the U.S. Food and Drug Administration (FDA).

16 Apr 2009

Somanetics announces new FDA 510(K) clearance

Somanetics Corporation has announced a new 510(k) clearance from the U.S. Food and Drug Administration (FDA) to expand the labeling for its INVOS(R) Cerebral/Somatic Oximeter.

16 Apr 2009

GlaxoSmithKline and Pfizer team up to form HIV company

Pharmaceutical companies GlaxoSmithKline and Pfizer today announced an "innovative agreement" to pool their HIV assets creating a new world-leading, specialist HIV company.

16 Apr 2009

Experts say propylthiouracil should not longer be used as first-line treatment for Graves' disease in children

Of the 4000 children with Graves' disease treated in the U.S. annually, 40 percent are routinely treated with the drug propylthiouracil.

16 Apr 2009

Slow-release anesthetic drug-delivery could change pain management

Researchers at Children's Hospital Boston have developed a slow-release anesthetic drug-delivery system that could potentially revolutionize treatment of pain during and after surgery, and may also have a large impact on chronic pain management.

15 Apr 2009