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Ophthalmologists find more evidence linking common bladder drug to retinal conditions

A drug widely prescribed for a bladder condition for decades, now appears to be toxic to the retina, the light sensing tissue at the back of the eye that allows us to see.

14 Oct 2019

Impress your boss with this course

In this webinar, Dr. Michael W. Dong, Pittcon Short Course Instructor, will review best practices, short cuts, and tricks-of-the-trade to help pharmaceutical and other scientists to become more successful in developing effective HPLC methods (potency and ICH-compliant stability-indicating assays) using method templates and universal generic gradient methods.

From Pittcon 14 Oct 2019

Caution urged in reducing opioids for pain

After years and decades in which healthcare providers were freely prescribing opiates for all sorts of painful conditions, the US Centers for Disease Control and Prevention (CDC) published guidelines to help bring down opioid prescription rates and with them, addiction and overdose-related death rates. Though these were not binding, they urged physicians to be cautious in dealing with opioids when prescribing for pain.

13 Oct 2019

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

The authors have developed the Accelera TED platform to repurpose drugs for HNSCC treatment; using in vitro assays and in vivo models.

11 Oct 2019

RTKI drugs may not significantly improve survival rates of patients during radiotherapy

Taking certain cancer-fighting drugs while undergoing radiation therapy may not increase survival for patients, but may, instead, increase side effects, according to a team of researchers. The drugs, however, may be beneficial for patients who are not undergoing radiation therapy.

10 Oct 2019

Vaccine against gastrin may slow spread of pancreatic cancer

New research suggests a vaccine that blocks a digestive hormone may slow the spread of pancreatic cancer, potentially increasing survival rates. The study, published ahead of print in the American Journal of Physiology—Gastrointestinal and Liver Physiology, was chosen as an APSselect article for October.

10 Oct 2019

‘Sticky’ gene may boost the nerve calming effects of Valium

Between 1999 and 2017, the United States experienced a 10-fold increase in the number of people who died from overdoses of Valium and other benzodiazepines.

10 Oct 2019

Scientists show how the immune system reacts to Ebola vaccine

Following the dramatic Ebola epidemic in West Africa from 2013 to 2016, viral infections have spread in the Democratic Republic of Congo since 2018. Since then, more than 2,100 deaths have been reported and the number of victims and new infections increases daily.

10 Oct 2019

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

Insilico Medicine, a company developing an end-to-end drug discovery pipeline utilizing the latest advances in deep learning, has entered into a two-program research collaboration agreement with Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd..

9 Oct 2019

New analysis examines the darknet's opioid purchases

U.S. overdose deaths attributed to synthetic opioids, such as fentanyl, have increased from under 3,000 in 2013 to nearly 20,000 in 2016, making up half of all opioid-related overdose deaths.

9 Oct 2019

Statin use linked with lower risk of developing prostate cancer

In a study of cancer-free men followed for a median of seven years, statin use was associated with a lower risk of developing prostate cancer.

9 Oct 2019

Statin use associated with increased risk of diabetes, skin infections

Statins have been reported to be beneficial for infections such as pneumonia and Staphylococcus aureus bacteremia.

9 Oct 2019

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Steroid therapy is commonly used to treat acute attacks of the inflammatory bowel diseases ulcerative colitis and Crohn's disease; however, because it does not provide long-term benefits and it carries a risk of serious side effects, it should not be used to treat inflammatory bowel disease for more than three months.

9 Oct 2019

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Researchers at the University of Arizona College of Medicine - Phoenix have shown for the first time in preclinical studies that Aliskiren, a drug that inhibits the enzyme that regulates blood pressure, can delay the progression of congestive heart failure and lengthen survival rates.

8 Oct 2019

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

Patients with advanced melanoma have been able to live longer because of several newly approved targeted treatment options, including BRAF and MEK inhibitors. However, patients will often have different responses to the same treatment due to genetic variability.

8 Oct 2019

Pharmaceutical News

Ophthalmologists find more evidence linking common bladder drug to retinal conditions

Impress your boss with this course

Caution urged in reducing opioids for pain

Repurposed quinacrine can reduce tumor burden in mice bearing HNSCC xenograft tumors

RTKI drugs may not significantly improve survival rates of patients during radiotherapy

Vaccine against gastrin may slow spread of pancreatic cancer

‘Sticky’ gene may boost the nerve calming effects of Valium

Scientists show how the immune system reacts to Ebola vaccine

Insilico and CTFH team up to expedite first-in-class therapeutics using AI platform

New analysis examines the darknet's opioid purchases

Statin use linked with lower risk of developing prostate cancer

Statin use associated with increased risk of diabetes, skin infections

Study explores steroid prescribing rates for patients with inflammatory bowel disease

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Differences at the single-cell level can predict responses to BRAF inhibitor therapy

New study to explore how medical cannabis affects people with chronic pain

Innovative study aims to improve care for patients using opioids for long-term pain

Health care market fails to support new antibiotics against superbugs, study finds

Antipsychotic use associated with higher accumulation of hospital days in Alzheimer's patients

Study: Essential medicines list in Canada should be evidence-based

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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