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Bortezomib drug helps re-balance disrupted muscle growth, prevent contractures

When children experience brachial plexus injury at birth, or are born with cerebral palsy, some of the most disabling problems that follow are muscle contractures, or tightness of muscles, that severely restrict limb function.

29 Oct 2019

Study shows significant decrease in use of antidepressants by pregnant women

A pregnancy is not always a happy event and as many as 10-15 per cent of pregnant women in Denmark have depressive symptoms. Despite years of critical focus on the side effects of antidepressants in the healthcare system, consumption of antidepressants by pregnant women actually increased drastically during the period 1997 to 2011.

29 Oct 2019

Gabapentinoid medications increasingly prescribed off-label for adults with cancer

Between 2005 and 2015, as the opioid crisis in America came into focus, prescriptions for gabapentinoid medications -- gabapentin and pregabalin -- to adults with cancer saw a two-fold increase, a University of Michigan Rogel Cancer Center study has found.

29 Oct 2019

Researchers investigate whether aspirin can decrease rate of intracranial aneurysm growth

Researchers conducted a database search to investigate whether aspirin can aid in the prevention of intracranial aneurysm rupture by hindering aneurysm growth. The researchers identified 146 patients harboring multiple intracranial aneurysms, five millimeters or less in diameter, that had been observed for at least five years.

29 Oct 2019

Moved overseas for school, stayed for insulin

Every now and then, Katie West considers returning to the United States. She moved to Germany for graduate school three years ago and now works as a health systems researcher in Hamburg. Her family is an ocean away. Then she remembers why she stays.

29 Oct 2019

Anti-inflammatory agents can safely, effectively reduce symptoms of major depression

Anti-inflammatory agents, such as aspirin/paracetamol, statins, and antibiotics, can safely and effectively curb the symptoms of major depression, finds a pooled analysis of the available evidence, published online in the Journal of Neurology Neurosurgery & Psychiatry.

29 Oct 2019

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

Novel antibodies could provide a universal flu vaccine

Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of viral cell surface antigen called neuraminidase (NA) that is necessary for viral replication.

28 Oct 2019

Work in progress on medicine for treatment of ulcerative colitis

IKBFU center for clinical research scientists have participated in the international VARSITY clinical research. It's the world's first research aimed at finding the most effective drug among anti-inflammatory ones for the treatment of ulcerative colitis.

28 Oct 2019

Cancer drug may delay progression of bone and other myeloma-related organ damage

The largest randomized trial in asymptomatic patients with smoldering multiple myeloma suggests that lenalidomide, a cancer drug, may delay the onset of bone and other myeloma-related organ damage.

28 Oct 2019

Molecular mechanisms involved in Pixantrone's interactions with cancer DNA discovered

Recently, a drug named Pixantrone (PIX) was developed, which is far less damaging to the heart than previous, less advanced compounds. PIX is now used to treat cancers including non-Hodgkin's lymphoma and leukaemia, but a detailed knowledge of the molecular processes it uses to destroy cancer cells has been lacking so far.

28 Oct 2019

New injectable formula to treat joint inflammation has sustained effect for ten days

Thanks to a new injectable formula, Brazilian researchers have succeeded in enhancing the efficacy and prolonging the duration of action of a drug commonly used to treat joint inflammation.

25 Oct 2019

Study compares safety and effectiveness of first-line antihypertensive drug classes

For those with extremely high blood pressure, or hypertension, there are many initial medication options -- so many that it can be hard to know which one to use.

25 Oct 2019

New ADA guideline: Antibiotics not recommended for toothaches

The American Dental Association announced today a new guideline indicating that in most cases, antibiotics are not recommended for toothaches.

25 Oct 2019

First-line antihypertensives may not be most effective, study shows

Thiazide diuretics demonstrate better effectiveness and cause fewer side effects than ACE inhibitors as first-line antihypertensive drugs, according to a report published Oct. 24 in The Lancet.

25 Oct 2019

Most popular first-line treatment for hypertension may be less effective than alternative drugs

A new multinational study shows that the most popular first-line treatment for hypertension is less effective and has more side effects than an alternative that's prescribed much less often.

25 Oct 2019

NIA-funded study to examine overall benefits and risks of statins in older adults

The National Institute on Aging has funded a major study to examine the overall benefits and risks of cholesterol-lowering drugs known as statins in adults age 75 or older without cardiovascular disease.

23 Oct 2019

Emory researchers awarded NIAID contract to develop better drug against influenza

With the flu killing an average of 20,000 people annually in the United States and posing the larger threat of global pandemics, Emory University's strides in influenza research carry the hope of saving lives here and abroad.

23 Oct 2019

Highest anxiety and sleeping pill prescription rates in deprived areas of England

The poorest and most socially deprived areas in England have the highest rates of prescription for benzodiazepines and Z-drugs, according to a new University of Warwick study published in the journal Family Practice on October 22, 2019.

23 Oct 2019

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

A research team from the School of Chinese Medicine at Hong Kong Baptist University has successfully developed a novel aptamer, i.e. a single-stranded piece of DNA, for the treatment of osteogenesis imperfecta (OI) with the aid of artificial intelligence (AI) technology.

23 Oct 2019

Pharmaceutical News

Bortezomib drug helps re-balance disrupted muscle growth, prevent contractures

Study shows significant decrease in use of antidepressants by pregnant women

Gabapentinoid medications increasingly prescribed off-label for adults with cancer

Researchers investigate whether aspirin can decrease rate of intracranial aneurysm growth

Moved overseas for school, stayed for insulin

Anti-inflammatory agents can safely, effectively reduce symptoms of major depression

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Novel antibodies could provide a universal flu vaccine

Work in progress on medicine for treatment of ulcerative colitis

Cancer drug may delay progression of bone and other myeloma-related organ damage

Molecular mechanisms involved in Pixantrone's interactions with cancer DNA discovered

New injectable formula to treat joint inflammation has sustained effect for ten days

Study compares safety and effectiveness of first-line antihypertensive drug classes

New ADA guideline: Antibiotics not recommended for toothaches

First-line antihypertensives may not be most effective, study shows

Most popular first-line treatment for hypertension may be less effective than alternative drugs

NIA-funded study to examine overall benefits and risks of statins in older adults

Emory researchers awarded NIAID contract to develop better drug against influenza

Highest anxiety and sleeping pill prescription rates in deprived areas of England

Hong Kong Baptist University receives FDA orphan drug designation for novel aptamer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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