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Study unravels how cancer medication works in brains of Parkinson's patients

Laboratory analysis from the first arm of a phase II clinical trial testing the use of nilotinib in patients with Parkinson's disease demonstrates precisely how the agent increases levels of dopamine in the brains of study participants, says a research team at Georgetown University Medical Center. Symptoms of Parkinson's, such as motor dysfunction, are a result of a dopamine loss.

13 Mar 2019

Precision cancer drugs spark powerful immune response and boost effects of immunotherapy

Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals.

11 Mar 2019

New guidelines on clinical use of life-saving antibiotics

An international panel of the foremost researchers on infectious disease and antimicrobials has formed new guidelines on the use of polymyxins, a class of antibiotics employed as a last resort to treat deadly, drug-resistant bacteria.

11 Mar 2019

Low adherence to cholesterol-lowering drugs also has beneficial effect in patients with type 2 diabetes

Type 2 diabetes patients' risk of cardiovascular disease and death decreases if they actually take the cholesterol-lowering drugs as prescribed. However, research shows that the risk is also reduced if they do not take the full dosage.

9 Mar 2019

Afternoon napping is as good as blood pressure pills, concludes study

A new study has shown that taking an afternoon nap could be as effective at lowering blood pressure as taking anti-hypertensive medication.

8 Mar 2019

Antibiotics and PPIs may increase risk of infectious diarrhea in children

Prior antibiotic exposure and use of acid suppressing medications known as proton pump inhibitors may increase the risk for hospitalized children to contract dangerous Clostridioides difficile infections, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

8 Mar 2019

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

SGLT-2 inhibitors are a relatively new class of diabetes drugs that have shown many benefits for people with type 2 diabetes who have not responded well to previous interventions, including diet changes and metformin.

8 Mar 2019

Women should not be alarmed by study linking HRT to Alzheimer’s disease

Doctors are encouraging women not to be alarmed by a study linking the use of hormone replacement therapy (HRT) with a slightly increased risk of Alzheimer’s disease.

7 Mar 2019

Cities and counties unlikely to heed FDA warning on importing foreign drugs

Cities and local governments in several states said they will continue to use a Canadian company to offer employees prescription drugs at a highly reduced price, even though federal officials raised safety concerns about the practice last week.

7 Mar 2019

Esketamine nasal spray approved for management of treatment-resistant depression

The United States Food and Drugs Administration (FDA) have approved for sale a new nasal spray containing Esketamine for the management of treatment-resistant depression.

6 Mar 2019

Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes

Individuals who take cholesterol-lowering statins may be at higher risk for developing high blood sugar levels, insulin resistance, and eventually type 2 diabetes, according to an analysis published in the British Journal of Clinical Pharmacology.

6 Mar 2019

Multivitamins do not help stave off depression but lifestyle coaching may work

A new study has contradicted the existing understanding that taking daily nutritional supplements may help to prevent depression.

6 Mar 2019

Patients experiment with prescription drugs to fight aging

Dr. Alan Green's patients travel from around the country to his tiny practice in Queens, N.Y., lured by the prospect of longer lives.

6 Mar 2019

Study to generate evidence on impact of pharmaceutical industry-led medicines access program

Study of Novartis Access program in Kenya demonstrates it is possible to evaluate major pharmaceutical companies' access programs using robust, 'gold standard' methods.

6 Mar 2019

Changing drugs, deprescribing do not lower severity and duration of delirium in ICU patients

The results of two new Regenstrief Institute trials published in the Journal of the American Geriatrics Society underscore and confirm the need to look to options other than medication to lower the duration or severity of delirium in intensive care unit patients.

6 Mar 2019

Gottleib resigns from FDA – issue of rising teen vaping remains unsolved

Scott Gottlieb, the commissioner of the United States Food and Drug Administration (FDA) has announced that he would resign from office at the end of this month.

5 Mar 2019

British man with HIV becomes second person ever to enter remission

A man in Britain has become the second person in the world to be cleared of HIV after receiving a stem cell transplant from an HIV-resistant donor.

5 Mar 2019

Study reveals increase in adverse outcomes for people taking aspirin and warfarin

A daily aspirin is a commonly used, generally safe therapy for people who need help preventing heart attacks or stroke.

5 Mar 2019

New ‘microdose’ psychedelic treatment appears to relieve anxiety and depression

Lava lamps, tambourines and, of course, psychedelic drugs were hallmarks of the 1960s. Psychedelic drugs can make people euphoric, though users can also become extremely anxious and agitated. But that's at a high dose.

5 Mar 2019

Translucent wonder material used on stadium roofs helps measure protein particles

Understanding how proteins clump together is essential in modern pharmaceuticals. When these tiny particles aggregate, they can alter the effectiveness of both vaccines and drugs, especially many of the new, popular formulations derived from monoclonal antibodies.

1 Mar 2019

Pharmaceutical News

Study unravels how cancer medication works in brains of Parkinson's patients

Precision cancer drugs spark powerful immune response and boost effects of immunotherapy

New guidelines on clinical use of life-saving antibiotics

Low adherence to cholesterol-lowering drugs also has beneficial effect in patients with type 2 diabetes

Afternoon napping is as good as blood pressure pills, concludes study

Antibiotics and PPIs may increase risk of infectious diarrhea in children

Research shows how SGLT-2 inhibitors induce a fasting state that triggers metabolic benefits

Women should not be alarmed by study linking HRT to Alzheimer’s disease

Cities and counties unlikely to heed FDA warning on importing foreign drugs

Esketamine nasal spray approved for management of treatment-resistant depression

Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes

Multivitamins do not help stave off depression but lifestyle coaching may work

Patients experiment with prescription drugs to fight aging

Study to generate evidence on impact of pharmaceutical industry-led medicines access program

Changing drugs, deprescribing do not lower severity and duration of delirium in ICU patients

Gottleib resigns from FDA – issue of rising teen vaping remains unsolved

British man with HIV becomes second person ever to enter remission

Study reveals increase in adverse outcomes for people taking aspirin and warfarin

New ‘microdose’ psychedelic treatment appears to relieve anxiety and depression

Translucent wonder material used on stadium roofs helps measure protein particles

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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