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Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Orbit Discovery Ltd., (“Orbit”) a privately held biopharmaceutical company focused on discovering candidate peptide therapeutics harnessing proprietary affinity and cell-based functional screening platforms, has been awarded a Smart grant by Innovate UK, the UK’s innovation agency.

From Orbit Discovery 14 Jun 2022

Evosep One enables robust, high throughput, single cell proteomics

Today, at the 70th Conference on Mass Spectrometry and Allied Topics, Evosep demonstrates new applications for standardization of high throughput single cell proteomics, higher throughput clinical analysis, and improved diabetes monitoring.

From Evosep 13 Jun 2022

Electro-chemical bandages could be an effective alternative to antibiotics for managing wound infections

According to new research by investigators at the Mayo Clinic and Washington State University, e-bandages could be an effective alternative to antibiotics for managing wound infections. The findings are presented at ASM Microbe 2022, the annual meeting of the American Society for Microbiology.

13 Jun 2022

Coffee consumption does not affect the absorption of liquid formulation of levothyroxine, study shows

Although current product labels and treatment guidelines recommend that patients take thyroid hormone replacement therapy on an empty stomach, new research suggests drinking coffee does not affect the absorption of a liquid formulation of levothyroxine (LT4).

13 Jun 2022

Prolonged use of puberty-delaying medicines among transgender youth linked to lower bone mineral density

A longer duration of treatment with puberty-delaying medications among transgender youth is associated with lower bone mineral density, according to a new study that will be presented Sunday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Animal study suggests intranasal COVID vaccine delivery more efficient than intramuscular

In a recent study published in the journal PNAS, researchers demonstrated higher comparative efficacy of the intranasal (IN) route of coronavirus disease 2019 (COVID-19) vaccine administration versus intramuscular route in mice.

12 Jun 2022

Inhaled vaccines provide better protection and stronger immunity than nasal sprays, study confirms

McMaster University scientists who compared respiratory vaccine-delivery systems have confirmed that inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays.

10 Jun 2022

Efficacy of BNT162b2 vaccine against SARS-CoV-2 Omicron sublineages and Deltacron

In a recent study posted to the bioRxiv* pre-print server, researchers at the University of Texas Medical Branch, Pfizer Vaccines Research & Development and BioNTech assessed the neutralization titers of sera from individuals vaccinated with the BNT162b2 coronavirus disease 2019 (COVID-19) vaccine and previously infected with the Omicron sublineage BA.1.

10 Jun 2022

Study finds Moderna COVID vaccine efficacy peaks at 94% after 120 days

A recent research letter posted to the JAMA Network Open assessed the durability of immunity conferred by the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA)-1273 vaccine.

10 Jun 2022

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID

In a recent study published in the Lancet, researchers evaluated the safety and efficacy of tixagevimab–cilgavimab, a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) combination in patients with mild to moderate coronavirus disease 2019 (COVID-19).

8 Jun 2022

Molnupiravir reduces hospitalizations and deaths in at-risk, unvaccinated adults with COVID

In a recent phase III study published in the New England Journal of Medicine, researchers demonstrated that oral molnupiravir was effective in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) therapy among non-vaccinated, non-hospitalized adults at-risk for severe illness.

8 Jun 2022

OpenSAFELY study shows the effectiveness of Pfizer COVID booster doses

In a recent study posted to the medRxiv pre-print server, researchers assessed the effectiveness of the Pfizer–BioNTech BNT162b2 coronavirus disease 2019 (COVID-19) vaccine in the seven million United Kingdom (UK) adults who were eligible to receive booster shots between 16 September and 16 December 2021.

7 Jun 2022

Study finds added benefits of molnupiravir for non-hospitalized COVID-19 patients

In a recent investigation published in the Annals of Internal Medicine journal, scientists demonstrated the positive impacts of molnupiravir among severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients and the healthcare sector apart from lowering disease-linked deaths and hospitalizations in at-risk cohorts.

7 Jun 2022

Inequalities found in oral anticoagulant prescribing to reduce stroke risk in atrial fibrillation patients

There are racial and socioeconomic inequalities in the prescribing of oral anticoagulants to reduce stroke risk in people with atrial fibrillation, according to a new study conducted in the UK and publishing June 7th in the open-access journal PLOS Medicine by Alyaa Ajabnoor of the University of Manchester, United Kingdom, and colleagues.

7 Jun 2022

Manufacturers and suppliers influence how pharmacies buy, distribute opioid prescriptions, study finds

In today's post-pandemic world, strained global supply chains have emerged as a new norm. But in the case of prescription opioids, namely oxycodone and hydrocodone in the early 2000s, that supply chain flowed freely without any kinks.

7 Jun 2022

Misinformation clouds America’s most popular emergency contraception

A brand of specialty mozzarella cheeses. A collection of natural-gas storage terminals. And America’s top-selling emergency contraception.

7 Jun 2022

California wants to slash insulin prices by becoming a drugmaker. Can it succeed?

California is diving into the prescription drug business, attempting to achieve what no other state has done: produce its own brand of generic insulin and sell it at below-market prices to people with diabetes like Sabrina Caudillo.

7 Jun 2022

New FR-targeting, micropinocytosis-mediated bioconjugate attacks K-Ras mutant pancreatic cancer

Often undetected until it has progressed to an advanced stage, pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer.

6 Jun 2022

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the immunogenicity of booster doses of alum-adjuvanted SCB-2019 vaccine candidate's three formulations.

6 Jun 2022

Pandemic-era changes to prescribing opioid use disorder treatment improved treatment outcomes

Pandemic-era changes to prescribing guidelines for the lifesaving drug buprenorphine led to improved treatment outcomes for patients with opioid use disorder in Philadelphia, according to a recently published study in the journal Drug and Alcohol Dependence Reports from researchers at Drexel University's Dornsife School of Public Health.

3 Jun 2022

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Pharmaceutical News

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Evosep One enables robust, high throughput, single cell proteomics

Electro-chemical bandages could be an effective alternative to antibiotics for managing wound infections

Coffee consumption does not affect the absorption of liquid formulation of levothyroxine, study shows

Prolonged use of puberty-delaying medicines among transgender youth linked to lower bone mineral density

Animal study suggests intranasal COVID vaccine delivery more efficient than intramuscular

Inhaled vaccines provide better protection and stronger immunity than nasal sprays, study confirms

Efficacy of BNT162b2 vaccine against SARS-CoV-2 Omicron sublineages and Deltacron

Study finds Moderna COVID vaccine efficacy peaks at 94% after 120 days

Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID

Molnupiravir reduces hospitalizations and deaths in at-risk, unvaccinated adults with COVID

OpenSAFELY study shows the effectiveness of Pfizer COVID booster doses

Study finds added benefits of molnupiravir for non-hospitalized COVID-19 patients

Inequalities found in oral anticoagulant prescribing to reduce stroke risk in atrial fibrillation patients

Manufacturers and suppliers influence how pharmacies buy, distribute opioid prescriptions, study finds

Misinformation clouds America’s most popular emergency contraception

California wants to slash insulin prices by becoming a drugmaker. Can it succeed?

New FR-targeting, micropinocytosis-mediated bioconjugate attacks K-Ras mutant pancreatic cancer

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

Pandemic-era changes to prescribing opioid use disorder treatment improved treatment outcomes

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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