cellenONE® is a comprehensive platform that seamlessly integrates high-accuracy single-cell isolation with precise pico- to nanoliter reagent dispensing.
- Image-based single-cell sorting and isolation
- Efficient cell line development with high clonal outgrowth
- Miniaturized, end-to-end workflows for single-cell sample preparation
While cellenONE X1 NEO is the ultimate platform for single cell proteomics, it is compatible with any single cell applications.
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Benefits
Accuracy
- Up to 100 % accuracy in single cells (no doublets, debris, or empty wells)
Miniaturization
- Reagent dispensing with high precision (from pico to nanoliter)
- On-deck temperature, humidity, and dew-point control
Image-based technology
- Live imaging of cell sample content (e.g., diameter and elongation)
- Sorting parameters can be user-defined (based on morphology or fluorescence)
- Image-based QC for each isolated cell
Versatility
- Any cell type (from 0.5 to ~80 µm)
- Any sample size (from ~ 3 µL)
- Any standard (i.e., 96, 384, 1536 well plates, glass slides, etc.) or custom labware
Viability
- Ultra-gentle, acoustic-based dispensing technology
- On-deck sample temperature control for enhanced cell viability (NEW)

Image Credit: SCIENION GmbH
Automation
- Enhanced drop generation system (NEW)
- Fully automated run creation and error handling (NEW)
- Rapid temperature ramping (4–85 °C) ensures effective sample incubation (NEW)
Ideal for rare cells
- Compatible with samples containing very few cells (e.g., micro-biopsies, CSF fluid)
- Supports ultra-low sample volumes (starting from ~3 µL)
- Maximized cell recovery—non-isolated cells are collected for further reprocessing
Time and cost savings
- Isolates 96 cells in under 3 minutes
- Miniaturized workflow to reduce reagent costs
- Automated workflow to minimize operator time
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Applications

Image Credit: Cellenion
How to isolate single cells with cellenONE from cellenion
Video Credit: Cellenion
Product specifications
Source: Cellenion
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Sorting Technology |
Brightfield and/or Multi-fluorescence
(Blue, Green, Orange and Red) images
DAPI (ex. 375 nm; em. 432 nm)
FITC (ex. 470 nm; em. 515 nm)
Cy3 (ex. 565 nm; em. 580 nm)
Cy5 (ex. 625 nm; em. 670 nm) |
Dispensing technology |
sciDROP PICO: 250-600 pL / single drop |
Target capacity |
2 MTPs or 8 standard glass slides |
Axis system |
X-Y Linear Magnetic Drive, Z Spindle Drive |
Axis precision |
< 3 μm |
Dimensions with enclosure
(L x Z x H) |
650 x 700 x 1590 mm |
Weight |
Approx. 242 kg |