Adrenal Gland News and Research

Latest Adrenal Gland News and Research

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant.

21 Jan 2015

Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

Sinai Hospital of Baltimore endocrinologist, Henry G. Fein, M.D., today presented new research showing that patients with Cushing's syndrome, a rare disease that can lead to extreme weight gain, type 2 diabetes, high blood pressure and psychological issues, experienced significant, sustained weight loss while taking oral medication daily over a number of years to manage symptoms of the disease.

25 Jun 2014

Single dose restores normal cellular signaling in mouse model of autism

In a further test of a novel theory that suggests autism is the consequence of abnormal cell communication, researchers at the University of California, San Diego School of Medicine report that an almost century-old drug approved for treating sleeping sickness also restores normal cellular signaling in a mouse model of autism, reversing symptoms of the neurological disorder in animals that were the human biological age equivalent of 30 years old.

18 Jun 2014

Forest publishes data from pivotal Phase III Study of Investigational FDC of nebivolol and valsartan

Forest Laboratories, Inc. (NYSE:FRX) today announced the publication of data from its pivotal Phase III Study of an Investigational Fixed-Dose Combination (FDC) of nebivolol and valsartan in the May 30, 2014 issue of The Lancet.

31 May 2014

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

A patient with advanced bladder cancer experienced a complete response for 14 months to the drug combination everolimus and pazopanib in a phase I trial, and genomic profiling of his tumor revealed two alterations that may have caused this exceptional response, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

13 Mar 2014

LMU researchers identify genetic mutations that result in overproduction of cortisol

An international team of researchers led by an endocrinologist at Ludwig-Maximilians-Universitaet (LMU) in Munich has identified genetic mutations that result in uncontrolled synthesis and secretion of the stress hormone cortisol.

28 Feb 2014

New study sheds light on the progression and management of ‘silent’ adrenal tumours

CT scans are increasingly performed for a variety of medical indications, including for general health screening, which is growing in popularity. An estimated 4% of CT scans will coincidentally uncover a tumour in the adrenal gland, with no associated clinical symptoms. However, until now, evidence on how to manage these ‘silent’ tumours has been lacking, despite the fact that the growing demand for CT scans is likely to lead to increasing numbers of detections.

30 Jan 2014

Study reveals why people are predisposed to cardiovascular disease and death

A genetic trait known to make some people especially sensitive to stress also appears to be responsible for a 38 percent increased risk of heart attack or death in patients with heart disease, scientists at Duke Medicine report.

19 Dec 2013

Study: Antisense drugs show activity in wide range of tissues and organs

Antisense therapeutics, a class of drugs comprised of short nucleic acid sequences, can target a dysfunctional gene and silence its activity. A new study has shown that antisense drugs delivered systemically show activity in a wide range of tissues and organs, supporting their broad therapeutic potential in many disease indications, as described in an article in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

13 Dec 2013

New data questions surgical options for treating kidney cancer

Surgery is often the first step in treating kidney cancer, and new data from the University of Rochester Medical Center, which contradicts earlier research, questions whether removal of only the tumor (partial nephrectomy) is better than removing the entire kidney (radical nephrectomy).

25 Jul 2013

IDIBELL signs patent licensing agreement with Minoryx

The Bellvittge Biomedical Research Institute has signed a licensing agreement with the Spanish biotechnology company Minoryx of a patent for the treatment of X-linked adrenoleukodystrophy, a rare serious neurodegenerative disease which has no effective treatment.

8 May 2013

Microwave ablation therapy reduces pain in patients with painful bone, soft-tissue tumors

First-of-its-kind research presented today showed microwave ablation therapy cut pain in half for patients with painful bone and soft-tissue tumors and took less time to complete than radiofrequency ablation.

15 Apr 2013

Mindfulness meditation can reduce stress hormone

Focusing on the present rather than letting the mind drift may help to lower levels of the stress hormone cortisol, suggests new research from the Shamatha Project at the University of California, Davis.

29 Mar 2013

Algorithm similar to Google PageRank helps map spread of lung cancer

The same sort of mathematical model used to predict which websites people are most apt to visit is now showing promise in helping map how lung cancer spreads in the human body, according to a new study published in the journal Cancer Research.

26 Mar 2013

Researchers: Acupuncture can reduce stress hormone response in animal model of chronic stress

While acupuncture is used widely to treat chronic stress, the mechanism of action leading to reported health benefits are not understood. In a series of studies at Georgetown University Medical Center, researchers are demonstrating how acupuncture can significantly reduce the stress hormone response in an animal model of chronic stress.

15 Mar 2013

Steroids used for treating TB may reduce death rates from all types of TB

The routine use of steroids to treat tuberculosis may help reduce deaths from all types of the disease, according to a new review of existing research.

14 Mar 2013

PCOS causes double jeopardy for those struggling hard to control glucose levels

Polycystic ovary syndrome, a condition affecting about 10 percent of women and characterized by excess male hormone and increased risk of diabetes and heart disease, appears to cause a sort of double jeopardy for those struggling the hardest to control blood sugar levels, researchers report.

14 Mar 2013

Newborn screening improves detection of lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys

Contrary to current belief, routine newborn screening improves the detection of the lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys, saving lives in both sexes, according to a unique study of CAH during the last 100 years published Online First in The Lancet Diabetes and Endocrinology.

27 Feb 2013

Early detection, treatment needed to reduce risk of death and CVD in older Cushing's disease patients

Even after successful treatment, patients with Cushing's disease who were older when diagnosed or had prolonged exposure to excess cortisol face a greater risk of dying or developing cardiovascular disease, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

13 Feb 2013

Investigators use genome analysis to eliminate lifetime drug prescription in two children

Using genome-wide analysis, investigators at the Sainte-Justine University Hospital Research Center and the University of Montreal have potentially eliminated a lifetime drug prescription that two children with a previously unknown type of adrenal insufficiency had been receiving for 14 years.

4 Feb 2013

Adrenal Gland News and Research

Latest Adrenal Gland News and Research

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Patients with Cushing’s syndrome experience significant weight loss while taking oral medication

Single dose restores normal cellular signaling in mouse model of autism

Forest publishes data from pivotal Phase III Study of Investigational FDC of nebivolol and valsartan

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

LMU researchers identify genetic mutations that result in overproduction of cortisol

New study sheds light on the progression and management of ‘silent’ adrenal tumours

Study reveals why people are predisposed to cardiovascular disease and death

Study: Antisense drugs show activity in wide range of tissues and organs

New data questions surgical options for treating kidney cancer

IDIBELL signs patent licensing agreement with Minoryx

Microwave ablation therapy reduces pain in patients with painful bone, soft-tissue tumors

Mindfulness meditation can reduce stress hormone

Algorithm similar to Google PageRank helps map spread of lung cancer

Researchers: Acupuncture can reduce stress hormone response in animal model of chronic stress

Steroids used for treating TB may reduce death rates from all types of TB

PCOS causes double jeopardy for those struggling hard to control glucose levels

Newborn screening improves detection of lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys

Early detection, treatment needed to reduce risk of death and CVD in older Cushing's disease patients

Investigators use genome analysis to eliminate lifetime drug prescription in two children

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Adrenal Gland News and Research

Latest Adrenal Gland News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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