Adrenal Gland News and Research

Latest Adrenal Gland News and Research

OSI Pharmaceuticals initiates two clinical trials with OSI-906 oral insulin-like growth factor-1 receptor inhibitor

OSI Pharmaceuticals, Inc. (NASDAQ: OSIP) announced today the initiation of two clinical trials with OSI-906, the Company’s potential first-in-class, oral insulin-like growth factor-1 receptor (IGF-1R) inhibitor. The first study is a Phase III, multi-center study that will evaluate the use of OSI-906 for patients with locally advanced or metastatic adrenocortical carcinoma (ACC).

4 Sep 2009

European Medicines Agency validates Schering-Plough's MAA for nomegestrol acetate/17 beta-estradiol

Schering-Plough Corporation, (NYSE: SGP), today announced that the European Medicines Agency (EMEA) has validated (accepted for review) the company's Marketing Authorization Application (MAA) for a fixed-dose combination of mometasone furoate and formoterol fumarate for the maintenance treatment of asthma in patients 12 years of age and older.

27 Aug 2009

Biological mechanisms contribute to stress resilience

It is important to understand what biological mechanisms contribute to an individual’s capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters.

5 Aug 2009

New findings on how stress causes sexual dysfunction and infertility

University of California, Berkeley, researchers have found what they think is a critical and, until now, missing piece of the puzzle about how stress causes sexual dysfunction and infertility.

16 Jun 2009

Study gives clues to how ultra-rare adrenocortical cancer forms

At the ends of chromosome are special pieces of DNA called telomeres. Think of it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it's the end point, not a break that should be repaired.

4 Jun 2009

Diabetic medication 'glibenclamide' may prevent nicotine-induced SIDS

According to researchers at McMaster University, exposure of the fetus to nicotine results in the inability to respond to decreases in oxygen - known as hypoxia - which may result in a higher incidence of SIDS.

3 Jun 2009

Overweight male teenagers with normal blood pressures showing signs of heart damage

Even while their blood pressures are still normal, overweight male teens may have elevated levels of a hormone known to increase pressures as well as early signs of heart damage, researchers say.

1 Jun 2009

DHEA supplement combined with vitamin D and calcium significantly improves spinal bone density in older women

"The results of our study are very promising. Similar studies have demonstrated much smaller benefits for bone than we found. However, calcium and vitamin D deficiencies, which are present in half of older adults, may have prevented DHEA from improving bone density in the earlier studies," said Edward Weiss, Ph.D., associate professor of nutrition and dietetics at Saint Louis University's Doisy College of Health Sciences and lead author of the study.

12 May 2009

Waiting for biopsy results may adversely affect health

Women who've had a breast biopsy know the anxiety of waiting for the results, but that stress may cause adverse health effects, according to a new study published in the March issue of Radiology.

24 Feb 2009

Researchers find novel use for old compound in cancer treatment

The compound, alpha-difluoromethylornithine or DFMO, targets the activity of a specific enzyme and, even in very limited doses, is effective in protecting against the malignancy in animal models.

19 Jan 2009

New technique produces genetically identical stem cells

Adult cells of mice created from genetically reprogrammed cells-so-called induced pluripotent stem (IPS) stem cells-can be triggered via drug to enter an embryonic-stem-cell-like state, without the need for further genetic alteration.

1 Jul 2008

Stress hormone impacts memory, learning in diabetic rodents

Diabetes is known to impair the cognitive health of people, but now scientists have identified one potential mechanism underlying these learning and memory problems.

18 Feb 2008

Smoking and SIDS

A new study sheds light on the relationship between women who smoke while pregnant or are exposed to second-hand smoke and an increased risk of SIDS to their babies.

30 Jan 2008

Radical and partial nephrectomy for kidney cancers

A new Mayo Clinic study suggests that removing the entire kidney from younger patients with small kidney tumors may lead to decreased overall survival compared with an operation that removes the tumor but leaves the kidney intact.

10 Jan 2008

A happy marriage bolsters a woman's physiological recovery from work

That's the suggestion from a new UCLA study that tracked levels of cortisol, a key stress hormone, among 30 Los Angeles married couples involved in one of our age's trickiest juggling acts - raising kids when both parents work full time.

2 Jan 2008

Discovery of master switch that regulates blood pressure

A team of Oregon Health & Science University researchers studying a rare form of hypertension has identified the mechanism by which they believe a protein complex in the kidney operates as a master switch that regulates blood pressure, a finding that has broad implications for the treatment of more common forms of hypertension.

2 Nov 2007