Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

Older women are different than older men. Their health is woefully understudied.

Medical research has shortchanged women for decades. This is particularly true of older women, leaving physicians without critically important information about how to best manage their health.

18 Jun 2024

New research explores maternal influence on brain biomarkers

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer's disease from their mother or father influences risk of biological changes in the brain that lead to disease. By evaluating 4,400 cognitively unimpaired adults ages 65-85, the team found those with a history of Alzheimer's disease (AD) on either their mother's side or both parents' sides had increased amyloid in their brains. Their results are published in JAMA Neurology.

18 Jun 2024

9/11 first responders face increased midlife dementia risk from severe dust exposure

Severe dust exposure among World Trade Center responders is linked to higher rates of dementia before age 65, highlighting long-term cognitive risks from 9/11.

17 Jun 2024

Protein aggregation: A new frontier in age-related disease detection

Could measuring protein clumps in our cells be a new way to find out our risk of getting age-related diseases? Professor Dorothee Dormann and Professor Edward Lemke of Johannes Gutenberg University Mainz (JGU), who are also adjunct directors at the Institute of Molecular Biology (IMB) in Mainz, propose the concept of a "protein aggregation clock" to measure aging and health in a new perspective article published in Nature Cell Biology.

17 Jun 2024

Americans with HIV are living longer. Federal spending isn’t keeping up.

Malcolm Reid recently marked the anniversary of his HIV diagnosis on Facebook. "Diagnosed with HIV 28 years ago, AND TODAY I THRIVE," he wrote in a post in April, which garnered dozens of responses.

17 Jun 2024

New link between sulfur metabolites in gut microbiome and neurodegenerative diseases revealed

Neurodegenerative diseases (NDDs), which have no known cures and elusive causes, result in irreversible damage to the brain and nervous system.

16 Jun 2024

Study reveals individual differences in fasting-induced ketosis and its health benefits

The study reveals that long-term fasting-induced ketosis varies among individuals and is influenced by factors like age, gender, and physical activity. It can also guide personalized fasting strategies.

16 Jun 2024

Exploring the comorbidities associated with osteoarthritis

Osteoarthritis is the most common arthritis worldwide, and has an increasing global burden of disability and healthcare utilization.

14 Jun 2024

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

A recent review outlines the necessary factors for widespread implementation and interpretation of Alzheimer's disease blood-based biomarkers (BBMs) at the population level, emphasizing the potential for early detection and improved diagnosis.

14 Jun 2024

Multiple head injuries significantly raise ischemic stroke risk, research shows

The rate of stroke in individuals with no history of prior stroke, was 34 percent higher in individuals who experienced at least one head injury than in their peers with no head injury.

13 Jun 2024

Nature and exercise: A combined approach to improving health outcomes

Health practitioners and fitness buffs have long known that regular physical activity offers numerous health benefits, including the prevention of chronic conditions such as cardiovascular disease, diabetes, some cancers and osteoporosis.

13 Jun 2024

MIT researchers develop revolutionary system for high-resolution brain imaging

A suite of three innovations by an MIT-based team enables high-resolution, high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution.

13 Jun 2024

Revolutionary platform unveils detailed human brain architecture at multiple scales

A new platform enables simultaneous capture of protein expression, cellular morphology, neural projection, and synapse distribution in large-scale human brain tissues at multiple scales, researchers report.

13 Jun 2024

Study links balanced neural activity to enhanced cognitive abilities in youth

In a world where external and internal stimuli can throw our entire body system off balance, how does our brain prevent itself from becoming overly stimulated?

13 Jun 2024

New research finds a way to delay vitamin B6 degradation

A low vitamin B6 level has negative effects on brain performance. A research team from Würzburg University Medicine has now found a way to delay the degradation of the vitamin.

13 Jun 2024

Combining donepezil and memantine extends lives of Alzheimer's patients, study finds

Alzheimer's disease is the world's most common neurodegenerative disease, affecting more than 50 million people globally.

12 Jun 2024

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

In response to stressful or dangerous stimuli, nerve cells in the spinal cord activate involuntary, autonomic reflexes often referred to as "fight or flight" responses.

12 Jun 2024

Prolonged depression in young adults linked to cognitive decline in middle age

People who experience prolonged depressive symptoms starting in young adulthood may have worse thinking and memory skills in middle age, according to a study published in the June 12, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2024

Low-birth-weight deliveries linked to cognitive decline in later life

People who give birth to infants less than 5.5 pounds may be more likely to have memory and thinking problems later in life than people who give birth to infants who do not have a low birth weight, according to a study published in the June 12, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jun 2024

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

Older women are different than older men. Their health is woefully understudied.

New research explores maternal influence on brain biomarkers

9/11 first responders face increased midlife dementia risk from severe dust exposure

Protein aggregation: A new frontier in age-related disease detection

Americans with HIV are living longer. Federal spending isn’t keeping up.

New link between sulfur metabolites in gut microbiome and neurodegenerative diseases revealed

Study reveals individual differences in fasting-induced ketosis and its health benefits

Exploring the comorbidities associated with osteoarthritis

Blood-based biomarkers could revolutionize Alzheimer's diagnosis and treatment

Multiple head injuries significantly raise ischemic stroke risk, research shows

Nature and exercise: A combined approach to improving health outcomes

MIT researchers develop revolutionary system for high-resolution brain imaging

Revolutionary platform unveils detailed human brain architecture at multiple scales

Study links balanced neural activity to enhanced cognitive abilities in youth

New research finds a way to delay vitamin B6 degradation

Combining donepezil and memantine extends lives of Alzheimer's patients, study finds

Study identifies drug target to prevent autonomic dysfunction after spinal cord injury

Prolonged depression in young adults linked to cognitive decline in middle age

Low-birth-weight deliveries linked to cognitive decline in later life

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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