Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mechanistic connections between vascular health and dementia risk in older adults

A new review paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Peripheral vascular dysfunction and the aging brain."

12 Jun 2024

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

With the advent of new omics technologies in recent years, there has been a deluge of complex, high-dimensional data on Alzheimer's disease (AD).

12 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

Caregivers' perceived age affects wellbeing of dementia patients

The felt age of spousal caregivers is connected to the felt age of their loved ones living with dementia, according to a study from the University of Surrey.

11 Jun 2024

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

11 Jun 2024

Patient perspectives highlight urgent need for research on smell and taste disorders

Researchers and patient advocates from the Monell Chemical Senses Center, Smell and Taste Association of North America (STANA), and Thomas Jefferson University came together during the COVID-19 pandemic to incorporate patient voices in efforts to prioritize research areas focused on improving care for people with smell and taste disorders.

10 Jun 2024

Vascular changes in pre-symptomatic stages of Huntington's disease offer new predictive potential

The genetic disease Huntington's not only affects nerve cells in the brain but also has widespread effects on microscopic blood vessels according to research.

10 Jun 2024

Can lifestyles changes reduce Alzheimer’s risk?

Intensive lifestyle changes significantly improve cognition and function in patients with mild cognitive impairment or early dementia due to Alzheimer’s disease over a 20-week period, showing promising results for non-pharmacological interventions.

10 Jun 2024

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

10 Jun 2024

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

When scientists transplanted the gut microbes of aged mice into young "germ-free" mice -; raised to have no gut microbes of their own -; the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans.

10 Jun 2024

New brain connectivity model predicts dementia years before diagnosis

Whether the default-mode network (DMN) effective connectivity can predict future dementia diagnosis at the individual level.

10 Jun 2024

Vigorous exercise linked to lower dementia risk in hypertensive individuals

The effect of vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia.

10 Jun 2024

Nursing homes are left in the dark as more utilities cut power to prevent wildfires

When powerful wind gusts created threatening wildfire conditions one day near Boulder, Colorado, the state's largest utility cut power to 52,000 homes and businesses — including Frasier, an assisted living and skilled nursing facility.

10 Jun 2024

Surprising link between a diverse oral microbiome and better cognitive function in aging

Study found that higher oral microbiome diversity is linked to better cognitive function and fewer memory issues in older US adults, highlighting the "oral-brain axis."

9 Jun 2024

Novel insights into the underlying, contributing, and direct causes of death in Australia

Coronary heart disease (CHD) was involved in 1 in 5 deaths in 2022 when using all of the information included on the medical death certificate, according to a new Australian Institute of Health and Welfare (AIHW) release revealing what Australians are most likely to die from.

8 Jun 2024

Changes in exploration behavior suggest early signs of cognitive decline in middle age

Spatial navigation – the ability to select and follow a route from one place to another – is a skill we use every day. Depending on practice, general cognitive ability, and childhood environment, some people are naturally better at this than others. But research has also shown that people’s skill in spatial navigation tends to decrease with increasing age.

8 Jun 2024

Vigorous exercise lowers dementia risk in hypertensive adults, study finds

People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study from researchers at Wake Forest University School of Medicine suggests that engaging in vigorous physical activity more than once a week can lower that risk.

7 Jun 2024

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

Pre-clinical trials: A new therapeutic approach for the severe condition uses modified viruses to replace a missing protein in the brain.

7 Jun 2024

New 5-minute cognitive test boosts dementia care in diverse elderly populations

The 5-Cog tool significantly enhances dementia diagnosis and care for older adults in primary care, especially among Black and Hispanic communities, by being culturally sensitive and quick to administer.

6 Jun 2024

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Mechanistic connections between vascular health and dementia risk in older adults

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Caregivers' perceived age affects wellbeing of dementia patients

Few UK Alzheimer's patients suitable for new disease-modifying drugs, study finds

Patient perspectives highlight urgent need for research on smell and taste disorders

Vascular changes in pre-symptomatic stages of Huntington's disease offer new predictive potential

Can lifestyles changes reduce Alzheimer’s risk?

Johns Hopkins researchers discover how epilepsy drug modulates brain activity

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

New brain connectivity model predicts dementia years before diagnosis

Vigorous exercise linked to lower dementia risk in hypertensive individuals

Nursing homes are left in the dark as more utilities cut power to prevent wildfires

Surprising link between a diverse oral microbiome and better cognitive function in aging

Novel insights into the underlying, contributing, and direct causes of death in Australia

Changes in exploration behavior suggest early signs of cognitive decline in middle age

Vigorous exercise lowers dementia risk in hypertensive adults, study finds

Novel therapeutic approach shows promise for frontotemporal dementia in pre-clinical trials

New 5-minute cognitive test boosts dementia care in diverse elderly populations

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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