Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Alzheimer's Association awards $4.2M grant to DIAN-Therapeutic Trials Unit

Washington University School of Medicine in St. Louis has received nearly $4.2 million from the Alzheimer's Association to accelerate the launch of the first clinical trials to prevent the symptoms of Alzheimer's disease.

21 Mar 2012

FKBP52 may prevent hyperphosphorylation of pathogenic Tau protein

New research in humans published today reveals that the so-called FKBP52 protein may prevent the Tau protein from turning pathogenic. This may prove significant for the development of new Alzheimer's drugs and for detecting the disease before the onset of clinical symptoms.

21 Mar 2012

Two new studies strongly support link between insulin resistance and Alzheimer's

An emerging body of research suggests that Alzheimer's disease may be linked to insulin resistance, constituting a third type of diabetes. This model is based on several observations including an increased risk of developing Alzheimer's disease for diabetic patients, and reduced insulin levels in the brain tissue of Alzheimer's disease patients. Though intriguing, the existing evidence does not reveal if defective insulin signaling is causative of Alzheimer's or how insulin resistance impacts cognitive function.

21 Mar 2012

Scientists investigate molecular mechanism of memory encoding in neurons

University of Alberta led research may have discovered how memories are encoded in our brains. Scientists understand memory to exist as strengthened synaptic connections among neurons. However components of synaptic membranes are relatively short-lived and frequently re-cycled while memories can last a lifetime.

20 Mar 2012

Heptares exercises exclusive option to license new A2A antagonist for CNS disorders

Heptares Therapeutics, the leading GPCR drug discovery company, announces that an operating company of Shire PLC, the global specialty biopharmaceutical company, has exercised its exclusive option to license a novel adenosine A2A antagonist discovered by Heptares that is currently in preclinical development.

20 Mar 2012

Health must be taken into account in climate change mitigation strategies

Health must be taken into account in climate change mitigation strategies. It is not widely appreciated that there are many benefits to health that are likely to accrue from a low carbon economy, say experts in a special supplement published on bmj.com today.

20 Mar 2012

Technique developed to identify rogue clustering proteins in brain diseases

Australian researchers have developed a novel technique that tracks proteins “behaving badly” and may have found a way that leads to new treatments for brain disease. The team believes the discovery could help in the development of drugs to treat diseases such as Alzheimer's, Parkinson's and Huntington's.

19 Mar 2012

Novel technique rapidly identifies and tracks location of diseased proteins inside cells

A research team led by the University of Melbourne, Australia, has developed a novel technique that tracks diseased proteins behaving badly by forming clusters in brain diseases such as Huntington's and Alzheimer's.

19 Mar 2012

Merz launches new, once daily Mederma Advanced Scar Gel

Mederma, the #1 doctor-and pharmacist-recommended brand for scars for over a decade, announced today the introduction of Mederma Advanced Scar Gel, which reduces the overall appearance of scars caused by injury, acne, surgery or burns with just one daily application. Mederma Advanced Scar Gel contains Cepalin, the same proprietary botanical extract derived from onions used in all Mederma® scar products and stretch marks therapy.

19 Mar 2012

Klf4 protein an important regulator of inflammation: HNK study

Microglia are the first line defence of the brain and are constantly looking for infections to fight off. Overactive microglia can cause uncontrolled inflammation within the brain, which can in turn lead to neuronal damage. New research published in BioMed Central's open access journal Journal of Neuroinflammation shows that, honokiol (HNK) is able to down-regulate the production of pro-inflammatory cytokines and inflammatory enzymes in activated microglia via Klf4, a protein known to regulate DNA.

19 Mar 2012

Pfizer supports First World Congress on Healthy and Active Ageing

As an official partner of the First World Congress on Healthy Ageing, Pfizer reaffirms the company's commitment to promote healthy and active ageing at all stages of life as a basis for enhanced productivity in the Asia Pacific. Pfizer will lead a luncheon symposium today focused on the relationship between health and economic sustainability and the resulting challenges and opportunities of shifting demographics across the region.

19 Mar 2012

SBMT announces 2012 recipients of Pioneers in Medicine, Technology and Healthcare Policy Awards

Today, the Society for Brain Mapping & Therapeutics announced the 2012 recipients of the organization's prestigious Pioneers in Medicine, Technology, and Healthcare Policy Awards.

17 Mar 2012

Radisphere announces availability of next 'Quality Update' piece

Radisphere, the only radiology provider offering proven accessibility and accountability to community hospitals, today announced availability of its next "Quality Update" piece as part of its "The Final Read on Quality" initiative.

17 Mar 2012

ApoE4 gene could cause early loss of synapses in Alzheimer's disease

Today, researchers at the Blanchette Rockefeller Neurosciences Institute (BRNI) at West Virginia University in Morgantown, West Virginia reported a significant advance in understanding how different forms of the ApoE gene raise the risk for Alzheimer's disease.

17 Mar 2012

SK Biopharmaceuticals initiates YKP10811 phase 2 trial in chronic constipation

SK Biopharmaceuticals, a South Korean pharmaceutical company, announced today that the first patient was dosed in a phase 2 clinical trial in the US for patients suffering with chronic constipation using their new chemical entity YKP10811.

17 Mar 2012

Older women with mild retinopathy more likely to have cognitive decline and related vascular changes

Women 65 or older who have even mild retinopathy, a disease of blood vessels in the retina, are more likely to have cognitive decline and related vascular changes in the brain, according to a multi-institutional study led by scientists at the University of California, San Francisco (UCSF).

16 Mar 2012

Eight European research institutes partner to provide training on systemic neuroscience

Eight European research institutes, including Johannes Gutenberg University Mainz (JGU), and three commercial partners have joined forces in an EU project to provide young academics with an outstanding research environment in the field of systemic neuroscience.

16 Mar 2012

Viewpoints: Health costs crushing Detroit; Military care still faces funding issues; Romneycare scores

Legacy costs are bankrupting Detroit just as they crushed its automakers. Firefighters can retire at 55 and earn 70% of their highest salary plus a 2.25% annual cost-of-living inflator in perpetuity. The result? Employee benefits alone now make up about half of the city's general fund. Health costs have grown by more than 60% since 2008 while the city's pension bill has quadrupled to $200 million.

16 Mar 2012

Combination therapy may improve life span and motor function of infants with Batten disease

Infants with Batten disease, a rare but fatal neurological disorder, appear healthy at birth. But within a few short years, the illness takes a heavy toll, leaving children blind, speechless and paralyzed. Most die by age 5.

16 Mar 2012

Women with retinopathy more likely to have cognitive problems

People with mild vascular disease that causes damage to the retina in the eye are more likely to have problems with thinking and memory skills because they may also have vascular disease in the brain, according to a study published in the March 14, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Mar 2012

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Alzheimer's Association awards $4.2M grant to DIAN-Therapeutic Trials Unit

FKBP52 may prevent hyperphosphorylation of pathogenic Tau protein

Two new studies strongly support link between insulin resistance and Alzheimer's

Scientists investigate molecular mechanism of memory encoding in neurons

Heptares exercises exclusive option to license new A2A antagonist for CNS disorders

Health must be taken into account in climate change mitigation strategies

Technique developed to identify rogue clustering proteins in brain diseases

Novel technique rapidly identifies and tracks location of diseased proteins inside cells

Merz launches new, once daily Mederma Advanced Scar Gel

Klf4 protein an important regulator of inflammation: HNK study

Pfizer supports First World Congress on Healthy and Active Ageing

SBMT announces 2012 recipients of Pioneers in Medicine, Technology and Healthcare Policy Awards

Radisphere announces availability of next 'Quality Update' piece

ApoE4 gene could cause early loss of synapses in Alzheimer's disease

SK Biopharmaceuticals initiates YKP10811 phase 2 trial in chronic constipation

Older women with mild retinopathy more likely to have cognitive decline and related vascular changes

Eight European research institutes partner to provide training on systemic neuroscience

Viewpoints: Health costs crushing Detroit; Military care still faces funding issues; Romneycare scores

Combination therapy may improve life span and motor function of infants with Batten disease

Women with retinopathy more likely to have cognitive problems

eBook: Hallmarks of Neurodegeneration eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Hallmarks of Neurodegeneration eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in