Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Investigational Alzheimer's compounds may treat neuropathies

Drugs already in development to treat Alzheimer's disease may eventually be tapped for a different purpose altogether: re-growing the ends of injured nerves to relieve pain and paralysis.

15 Apr 2011

Treatment of vascular risk factors may lower risk of Alzheimer's disease

Treating high blood pressure, high cholesterol, diabetes and other vascular risk factors may help lower the risk of Alzheimer's disease in people who already show signs of declining thinking skills or memory problems. The research is published in the April 13, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

15 Apr 2011

AAN, PDF honor Boston researcher with Clinician Scientist Development Award

A clinician scientist at Massachusetts General Hospital in Boston is receiving $240,000 to further his research into how stem cells may be used to treat Parkinson's disease through the American Academy of Neurology Foundation and the Parkinson's Disease Foundation Clinician Scientist Development Award in Parkinson's Disease Research.

15 Apr 2011

NIST's new reference can aid in Huntington's disease diagnosis

A new Standard Reference Material from the National Institute of Standards and Technology will help clinical genetics labs accurately diagnose Huntington's disease, an inherited degenerative brain disorder that usually begins between ages 35 and 50 and progressively leads to physical impairment, dementia and death.

15 Apr 2011

Brain damage starts decade earlier in Alzheimer’s patients

A new study published in the journal Neurology has shown that the brains of people diagnosed with Alzheimer's disease start shrinking up to a decade before symptoms appear. Researchers from Rush University Medical Center in Chicago and Massachusetts General Hospital in Boston did brain imaging tests on older adults with no signs of memory loss.

15 Apr 2011

Manage type 2 diabetes to reduce risk of Alzheimer’s

A new study from a team of Chinese researchers has shown that controlling type 2 diabetes symptoms may produce many health benefits including a decreased risk of Alzheimer's disease.

15 Apr 2011

Perampanel drug can effectively treat seizures in patients with epilepsy

A new drug called perampanel appears to significantly reduce seizures in people with hard-to-control epilepsy, according to results of the first clinical trial to test the higher 12 mg dose of the drug.

15 Apr 2011

Ortho-McNeil Neurologics announces voluntary recall of TOPAMAX 100mg Tablets

Ortho-McNeil Neurologics Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., today announced it is voluntarily recalling two lots of TOPAMAX® (topiramate) 100mg Tablets. These two lots were shipped between 10/19/2010 and 12/28/2010 and distributed in the U.S. and Puerto Rico.

15 Apr 2011

Study finds association between C-reactive protein and memory decline

High levels of a protein associated with chronic, low-grade inflammation in the brain correlate with aspects of memory decline in otherwise cognitively normal older adults, according to a study led by scientists at the University of California, San Francisco.

15 Apr 2011

Brain starts shrinking in Alzheimer’s disease a decade earlier: Study

According to American researchers, brain scans of healthy people showed signs that the brain was shrinking in Alzheimer's-affected areas nearly a decade before the disease was diagnosed. This comes in the latest issue of the journal Neurology and it may offer a new way to detect the disease early, an advance that could help in the development of effective treatments for Alzheimer's, a brain-wasting disease that affects up to 26 million people globally.

13 Apr 2011

Insight into neurodegenerative diseases

For years, researchers in genome stability have observed that several neurodegenerative diseases-including Huntington's disease-are associated with cell-killing proteins that are created during expansion of a CAG/CTG trinucleotide repeat.

12 Apr 2011

Laquinimod drug greatly reduces number of relapses in patients with MS

The drug laquinimod reduced the number of relapses for people with multiple sclerosis, in a large, long-term Phase III clinical study that will be presented as late-breaking research at the 63rd Annual Meeting of the American Academy of Neurology, April 9-16, 2011, in Honolulu.

12 Apr 2011

New guideline on most effective treatments for diabetic nerve pain

The American Academy of Neurology has issued a new guideline on the most effective treatments for diabetic nerve pain, the burning or tingling pain in the hands and feet that affects millions of people with diabetes. The guideline is published in the April 11, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology, and will be presented April 11, 2011, at the American Academy of Neurology's Annual Meeting in Honolulu.

12 Apr 2011

New research: MRI can help detect early stage Alzheimer's disease

New research suggests that magnetic resonance imaging could help detect Alzheimer's disease at an early stage, before irreversible damage has occurred, according to a new study published online and in the June print edition of Radiology.

12 Apr 2011

Alzheimer’s drug – a failure of sorts: Study

Results from the study shows that drug, memantine, is no better than a dummy pill when it comes to ameliorating disease symptoms, including the decline of mental abilities and also helping patients with moderate Alzheimer's, the researchers say. Sold under the brand Namenda by Forest Laboratories Inc and Germany's Merz Pharma, the drug had U.S. sales of about $1.2 billion last year.

11 Apr 2011

Air pollution on freeways may lead to brain damage: Study

Earlier research has shown that air pollution from cars and trucks on Southern California freeways – that contains soot, pavement dust and other toxic substances - can cause respiratory disease, heart attacks, cancer and premature death. Now a new study has shown that exposure to pollution particles roughly one-thousandth the width of a human hair may lead to brain damage in mice, including signs associated with memory loss and Alzheimer’s disease. The study comes from University of Southern California and is published in the journal Environmental Health Perspectives.

10 Apr 2011

Reduction in alcohol prices increases alcohol-related mortality

Does a reduction in the price of alcohol result in an increase in deaths due to alcohol? This was the subject of a study following a significant reduction in taxes in Finland in 2004 (30% for spirits, 3% for wine).The abolition of import quotas by the EU in 2004 also made it possible to import from other member countries and this led to an increase of approximately 10% in alcohol consumption in Finland.

8 Apr 2011

Canadian political parties called upon to focus on health system during election campaign

The Health Action Lobby today called on all political parties to focus on the health system during the federal election campaign. HEAL is a coalition of 35 national health organizations that represents a broad cross-section of health providers, health regions, institutions & facilities.

8 Apr 2011

Targacept's TC-5619 Phase 2 trial data in schizophrenia presented at ICOSR

Targacept, Inc. today announced the presentation of data from a Phase 2 clinical proof of concept trial to assess TC-5619 as an augmentation therapy to improve cognition in patients with schizophrenia at the International Congress on Schizophrenia Research in Colorado Springs, Colorado.

8 Apr 2011

CoMeD urges UN to ban mercury use in pharmaceuticals

While the United Nations actively questions the use of a vaccine preservative that contains the known neurotoxin mercury, the Coalition for Mercury-Free Drugs, a Maryland-based, non-profit organization, is urging the UN to ban it.

7 Apr 2011