Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Drug cocktail that increases lifespan discovered

A team of researchers led by Principal Investigator Dr Jan Gruber from Yale-NUS College has discovered a combination of pharmaceutical drugs that not only increases healthy lifespan in the microscopic worm Caenorhabditis elegans (C. elegans), but also delays the rate of ageing in them, a finding that could someday mean longer, healthier lives for humans.

22 Oct 2018

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck, known as MSD outside the United States and Canada, today announced the first presentation of preliminary data from a Phase 1 clinical trial evaluating MK-1454, an investigational STING (stimulator of interferon genes) agonist, as monotherapy and in combination with KEYTRUDA (pembrolizumab), Merck's anti-PD-1 therapy, in patients with advanced solid tumors or lymphomas.

22 Oct 2018

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

Merck, known as MSD outside the United States and Canada, today announced the first presentation of results from an interim analysis of KEYNOTE-057, a Phase 2 trial evaluating KEYTRUDA, Merck's anti-PD-1 therapy, for previously treated patients with high-risk non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ or CIS plus papillary disease (Cohort A).

22 Oct 2018

FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

Genentech, a member of the Roche Group, announced today that the U.S. Food and Drug Administration has approved an update to the Rituxan® (rituximab) label to include information on follow up treatment of adult patients with Granulomatosis with Polyangiitis and Microscopic Polyangiitis who have achieved disease control with induction treatment.

22 Oct 2018

Immune therapy may be potential treatment option for patients with hard-to-treat ankylosing spondylitis

Results from a phase 3 clinical trial indicate that patients who have not benefited from standard therapy for ankylosing spondylitis, a chronic inflammatory disease characterized by back pain and sacroiliac-joint damage, may have another treatment option in the biologic drug ixekizumab.

22 Oct 2018

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

A bioelectronic medicine device was effective in reducing pain and fatigue in patients with lupus, according to Feinstein Institute for Medical Research Professor Cynthia Aranow, MD, who will present pilot clinical trial results Tuesday at the American College of Rheumatology/Association of Rheumatology Professional's Annual Meeting.

22 Oct 2018

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Gilead Sciences, Inc. and Galapagos NV today announced detailed results from the Phase 3 FINCH 2 clinical trial of filgotinib, an investigational, selective JAK1 inhibitor, in adults with moderately-to-severely active rheumatoid arthritis and prior inadequate response or intolerance to biologic agents.

22 Oct 2018

Study reveals connection between two proteins known to be hyperactive in cancer

A team of researchers at Baylor College of Medicine and Texas Children's Hospital has revealed a connection between mTORC1 and Src, two proteins known to be hyperactive in cancer.

20 Oct 2018

NSF awards $5 million grant to help scientists magnify societal impact of research

When Humira came on the market, many found relief from symptoms of arthritis, plaque psoriasis, Crohn’s disease and ulcerative colitis.

19 Oct 2018

$11 million NIH grant for Clemson University helps launch new center for musculoskeletal research

With an $11 million grant from the National Institutes of Health Center for Biomedical Research Excellence, Clemson University has launched the South Carolina Center for Translational Research Improving Musculoskeletal Health, or SC-TRIMH, a new research center that will bring together scientists from across South Carolina to change the way musculoskeletal disorders are diagnosed, treated and even studied.

19 Oct 2018

Study: Nurse-led care can be more successful in managing gout

Providing nurse-led care for people suffering with the painful, long-term condition gout could lead to an increase in the number of patients sticking to a beneficial treatment plan, a clinical trial has revealed.

19 Oct 2018

Research points to new target for treating periodontitis

T cells help fight off infection, but they can go overboard. A new study led by researchers at the University of Pennsylvania School of Dental Medicine and the National Institutes of Health shows that a subset of T cells contributes to the problematic inflammation and bone loss that is associated with periodontitis, a severe form of gum disease.

17 Oct 2018

Study reveals link between childhood abuse and higher arthritis risk in adulthood

In a survey-based study of 21,889 adults in Canada, severe and/or frequent physical abuse during childhood and frequent childhood exposure to intimate partner violence were linked with higher risks or arthritis during adulthood arthritis, even after controlling for a range of factors. The findings are published in Arthritis Care & Research.

17 Oct 2018

New project aims to deliver fast, effective treatment for autoimmune rheumatic diseases

Affecting around 2 % of the population, autoimmune rheumatic diseases can have severe symptoms, including painful and swollen joints, fever, rashes, fatigue and sensitivity to the sun, with patients needing regular check-ups.

15 Oct 2018

King's commemorates activities and research on World Arthritis Day

King's has a long history with arthritis research and been recognised as having one of the premier rheumatology research units in Europe.

12 Oct 2018

World Arthritis Day: New campaign raises awareness for early diagnosis of rheumatic diseases

The European League Against Rheumatism, EULAR, calls for people to come together on World Arthritis Day (12th October) to raise awareness of rheumatic and musculoskeletal diseases. EULAR's Don't Delay, Connect Today Campaign aims to improve early diagnosis and timely access to care to help benefit the lives of the 120 million people in Europe with RMDs.

12 Oct 2018

Top journal publishes special issue on deep learning for drug discovery and biomarker development

While the many concepts in artificial intelligence date back to the 20th century, the revolution in deep learning started around 2014-2015 when AI systems started outperforming humans in many tasks ranging from video games and image recognition to autonomous driving.

11 Oct 2018

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Studies in mice have demonstrated that obesity-induced inflammation contributes to the risk of colorectal cancer, but evidence in humans has been scarce.

11 Oct 2018

Study sheds light on lupus's autoimmune origins in precursor cells

In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been unclear, but recent research from Emory University School of Medicine sheds light on a missing link.

11 Oct 2018

Cleveland Clinic awarded $6 million NIH grant to study techniques used for ACL reconstruction

The National Institute of Arthritis and Musculoskeletal and Skin Diseases, part of the National Institutes of Health, has awarded Cleveland Clinic $6 million to study techniques used for anterior cruciate ligament reconstruction.

10 Oct 2018

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Drug cocktail that increases lifespan discovered

Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas

Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer

FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis

Immune therapy may be potential treatment option for patients with hard-to-treat ankylosing spondylitis

Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus

Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting

Study reveals connection between two proteins known to be hyperactive in cancer

NSF awards $5 million grant to help scientists magnify societal impact of research

$11 million NIH grant for Clemson University helps launch new center for musculoskeletal research

Study: Nurse-led care can be more successful in managing gout

Research points to new target for treating periodontitis

Study reveals link between childhood abuse and higher arthritis risk in adulthood

New project aims to deliver fast, effective treatment for autoimmune rheumatic diseases

King's commemorates activities and research on World Arthritis Day

World Arthritis Day: New campaign raises awareness for early diagnosis of rheumatic diseases

Top journal publishes special issue on deep learning for drug discovery and biomarker development

Inflammatory proteins in the colon increase in parallel with increasing weight, study shows

Study sheds light on lupus's autoimmune origins in precursor cells

Cleveland Clinic awarded $6 million NIH grant to study techniques used for ACL reconstruction

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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