Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

New research on molecular mechanistic understanding of drug delivery and drug delivery systems

Today, Insilico Medicine, Inc., a Rockville-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper "Entangled Conditional Adversarial Autoencoder for de-novo Drug Discovery" in Molecular Pharmaceutics, the leading American Chemical Society journal covering research on the molecular mechanistic understanding of drug delivery and drug delivery systems

12 Sep 2018

Alivio Therapeutics receives DoD grant to advance development of new therapy for IC/BPS

Alivio Therapeutics, an affiliate of PureTech Health plc developing therapies to treat inflammatory disorders through targeted disease immunomodulation, today announced a $3.3 million U.S. Department of Defense Technology/Therapeutic Development Award to advance Alivio's product candidate, ALV-107, for the treatment of interstitial cystitis/bladder pain syndrome with Hunner's lesions.

12 Sep 2018

Survey: Psoriasis patients expect treatment to go beyond just clear skin and safety

Novartis, a leader in immuno-dermatology, announced today new data from a patient preference survey showing psoriasis patients want their treatment to go beyond just clear skin and safety.

12 Sep 2018

Nearly one in three opioid prescriptions in the US not justified, finds analysis

According to a nationwide analysis of physician visit records conducted by a team of researchers at Harvard Medical School and the RAND Corporation, nearly 30 percent of the outpatient opioid prescriptions made out in the United States do not have documented justification for their use.

12 Sep 2018

Study raises concerns about inappropriate opioid prescribing, lax documentation practices

Nearly 30 percent of outpatient opioid prescriptions in the United States lack documented clinical reasons that justify the use of these potent drugs, according to a national analysis of physician visit records conducted by researchers at Harvard Medical School and the RAND Corporation.

11 Sep 2018

Mouse study suggests new therapeutic approach to treat heart failure

A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death.

10 Sep 2018

ACR cautions policymakers that reducing E/M services can compromise patient access to care

In comments submitted to the Centers for Medicare and Medicaid Services regarding the 2019 Medicare Physician Fee Schedule proposed rule, the American College of Rheumatology cautioned policymakers against implementing a proposal to reduce physician reimbursement for evaluation and management services, arguing that doing so could severely compromise patient access to care and further exacerbate the growing rheumatology workforce shortage.

10 Sep 2018

Metabolic dysfunction drives chronic illness

Much of modern Western medicine is based upon the treatment of acute, immediate harm, from physical injury to infections, from broken bones and the common cold to heart and asthma attacks.

7 Sep 2018

A joint effort to provide new insights into how gene activity drives cartilage development

Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, PhD, collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage.

7 Sep 2018

Imaging with CMR can improve detection of cardiac injury in lupus patients

The number of diagnoses of systemic lupus erythematodes has tripled over the past 45 years - due in part to improved diagnostic methods.

7 Sep 2018

Total ankle arthroplasty boosts patients' range of motion and improves quality of life

Surgical reconstruction is a life changer for people with end-stage ankle arthritis, a painful condition that limits patients' abilities to go up and down stairs, get out of a car and even walk.

6 Sep 2018

Breakthrough fluorine discovery may impact how pharmaceutical companies develop new drugs

A groundbreaking discovery by chemists at The University of Texas at San Antonio will have a significant impact on how pharmaceutical companies develop new drug treatments.

6 Sep 2018

Powerful antioxidant can lower the risk of second heart attack or stroke

Doctors have long known that in the months after a heart attack or stroke, patients are more likely to have another attack or stroke. Now, a paper in the Journal of the American College of Cardiology explains what happens inside blood vessels to increase risk - and suggests a new way to treat it.

5 Sep 2018

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time.

4 Sep 2018

Neutrophil nanosponges provide hope for rheumatoid arthritis

Scientists in San Diego have developed nanosponges coated in neutrophil membranes that can prevent rheumatoid arthritis.

3 Sep 2018

TGHRI scientists detail role of insulin as a boost to the immune system

The role of insulin as a boost to the immune system to improve its ability to fight infection has been detailed for the first time by Toronto General Hospital Research Institute scientists.

30 Aug 2018

OSA patients have higher risk of developing gout, research reveals

New research reveals that people with obstructive sleep apnea (OSA) have a higher risk of developing gout, even beyond the first years after being diagnosed with the sleep disorder. The findings are published in Arthritis & Rheumatology, an official journal of the American College of Rheumatology.

30 Aug 2018

$Genome-wide association study provides insight into biologic mechanisms leading to fractures$

Genome-wide association study provides insight into biologic mechanisms leading to fractures

A paper titled "Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomization study" appeared today in the British Medical Journal.

30 Aug 2018

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Immune reactions are usually a good thing-;the body's way of eliminating harmful bacteria and other pathogens. But people also rely on molecular "brakes," or checkpoints, to keep immune systems from attacking their own cells and organs and causing so-called autoimmune disease.

29 Aug 2018

New safety guideline released for prescribing biological therapies in inflammatory arthritis

The British Society for Rheumatology publishes its latest clinical guideline in Rheumatology, the UK’s key specialist journal in the sector. The new guideline updates and presents two previous guidelines into one set of evidence based recommendations on the vital safety aspects of prescribing biological therapies in inflammatory arthritis.

28 Aug 2018

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

New research on molecular mechanistic understanding of drug delivery and drug delivery systems

Alivio Therapeutics receives DoD grant to advance development of new therapy for IC/BPS

Survey: Psoriasis patients expect treatment to go beyond just clear skin and safety

Nearly one in three opioid prescriptions in the US not justified, finds analysis

Study raises concerns about inappropriate opioid prescribing, lax documentation practices

Mouse study suggests new therapeutic approach to treat heart failure

ACR cautions policymakers that reducing E/M services can compromise patient access to care

Metabolic dysfunction drives chronic illness

A joint effort to provide new insights into how gene activity drives cartilage development

Imaging with CMR can improve detection of cardiac injury in lupus patients

Total ankle arthroplasty boosts patients' range of motion and improves quality of life

Breakthrough fluorine discovery may impact how pharmaceutical companies develop new drugs

Powerful antioxidant can lower the risk of second heart attack or stroke

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Neutrophil nanosponges provide hope for rheumatoid arthritis

TGHRI scientists detail role of insulin as a boost to the immune system

OSA patients have higher risk of developing gout, research reveals

Genome-wide association study provides insight into biologic mechanisms leading to fractures

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

New safety guideline released for prescribing biological therapies in inflammatory arthritis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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