Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Can-Fite reports positive results from CF101 Phase IIb study for rheumatoid arthritis

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced results from a 12-week, placebo-controlled Phase IIb study involving 79 patients with active rheumatoid arthritis ("RA") for its proprietary drug CF101, an A3 adenosine receptor ("A3AR") agonist.

23 Dec 2013

Death rates two times higher in postmenopausal women with anti-CCP and RA antibodies

New research shows mortality rates are two times higher in postmenopausal women with rheumatoid arthritis (RA) and anti-cyclic citrullinated peptide (anti-CCP) antibodies. Findings published in the American College of Rheumatology (ACR) journal Arthritis & Rheumatism, soon to be called Arthritis & Rheumatology, indicate the higher mortality rates persisted after adjusting for age, positive rheumatoid factor, positive antinuclear antibodies (ANA) and disease modifying anti-rheumatic drug (DMARD) use.

23 Dec 2013

Six common diseases arise from DNA changes, finds new research

Many rare disorders are caused by gene mutation, like sickle cell anemia. Yet until now the underlying genetic cause of more common conditions - for example, rheumatoid arthritis - has evaded scientists for years.

22 Dec 2013

Antares Pharma receives Notice of Allowance for new patent application on reconstitutable drugs

Antares Pharma, Inc. today announced that it has received a Notice of Allowance from the U.S. Patent Office for application 13/584,317. This application, along with U.S. Patent 8,251,947 granted in August of 2012, relate to Antares' injector technology for wet-dry injectable drugs such as lyophilized biologicals or peptide drugs that require dry storage to assure stability.

20 Dec 2013

Solana's CrossCHECK Plating System receives FDA clearance

Solana Surgical, LLC, a growth extremity company, announces the FDA Clearance of the CrossCHECK™ Plating System, a new implant system for orthopedic and podiatric surgeons' use in foot and ankle procedures. Commercialization will follow in the first quarter of 2014.

20 Dec 2013

Hispanic mortality paradox found in RA patients

The so-called “Hispanic survival paradox” has been found to extend to patients with rheumatoid arthritis, whereby Hispanic people with the condition tend have more severe symptoms but equivalent mortality to non-Hispanic White individuals.

19 Dec 2013

Helsinn, Mundipharma sign distribution and license agreement for investigational therapy

Helsinn and Mundipharma announce the signature of a new, exclusive license and distribution agreement, covering China, Hong Kong and Macao, for netupitant-palonosetron fixed dose combination, a Helsinn product under development for the treatment of chemotherapy-induced nausea and vomiting.

19 Dec 2013

Sanofi and Regeneron Pharmaceuticals team up with ACC to enhance clinical research with alirocumab

Sanofi and Regeneron Pharmaceuticals, Inc. today announced an innovative collaboration with the American College of Cardiology focused on enhancing clinical research with alirocumab, an investigational monoclonal antibody targeting PCSK9 (proprotein convertase subtilisin/kexin type 9). PCSK9 is known to contribute to circulating low-density lipoprotein cholesterol (LDL-C) levels. Alirocumab is being co-developed by Sanofi and Regeneron.

19 Dec 2013

Regenerative medicine may offer ways to banish baldness

Regenerative medicine may offer ways to banish baldness that don't involve toupees. The lab of USC scientist Krzysztof Kobielak, MD, PhD has published a trio of papers in the journals Stem Cells and the Proceedings of the National Academy of Sciences (PNAS) that describe some of the factors that determine when hair grows, when it stops growing and when it falls out.

19 Dec 2013

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

People with intermittent explosive disorder — a psychiatric illness characterized by impulsivity, hostility and recurrent aggressive outbursts — have elevated levels of two markers of systemic inflammation in their blood, according to a study involving nearly 200 subjects.

19 Dec 2013

FDA accepts Regeneron's EYLEA Injection sBLA for standard review

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has accepted for standard review the Company's supplemental Biologics License Application for EYLEA (aflibercept) Injection for the treatment of Diabetic Macular Edema.

18 Dec 2013

Primary cilia play key role in stem cell differentiation

Researchers at Queen Mary University of London have shown for the first time that the specialised role stem cells go on to perform is controlled by primary cilia -tiny hair-like structures protruding from a cell.

18 Dec 2013

Chronic pain amongst different ethnic groups: an interview with Professor Martin Underwood, Warwick Medical School

Conventionally chronic pain is defined as pain that lasts beyond the expected period of healing. Most experts consider a pain to be chronic after three months.

18 Dec 2013

Nonsurgical treatment of periodontal disease does not improve glycemic control in patients with diabetes

A recent study published in the Journal of the American Medical Association (JAMA) found that nonsurgical treatment of periodontal disease does not improve glycemic control in patients with type 2 diabetes.

18 Dec 2013

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Researchers from Echelon Biosciences, Inc. and collaborators from the University of Utah report the use of ATX-Red AR-2 as a new imaging agent that effectively illuminates tumors.

17 Dec 2013

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Investigators at The Feinstein Institute for Medical Research have discovered for the first time, direct evidence of a genetic overlap between schizophrenia and general cognitive ability. The findings are published online in Molecular Psychiatry.

17 Dec 2013

Biogen joins with Samsung Bioepis to commercialize anti-TNF biosimilar product candidates in Europe

Biogen Idec (NASDAQ: BIIB) and Samsung Bioepis today announced that through their joint venture, Biogen Idec has exercised its right to enter into an agreement to commercialize anti-TNF biosimilar product candidates in Europe, including biosimilars for widely used therapies to treat conditions such as rheumatoid arthritis and Crohn's disease.

17 Dec 2013

Scientists identify protein complex essential for jumpstarting immune response during infection

St. Jude Children's Research Hospital scientists have identified a protein complex that is essential for jumpstarting the immune response during the critical first 24 hours of an infection. The research appears in the current issue of the scientific journal Immunity.

17 Dec 2013

Utah researchers discover naturally occurring genetic variation that cause inflammatory arthritis

University of Utah researchers have discovered a naturally occurring genetic variation in mice that predisposes carriers toward developing severe, inflammatory arthritis. The finding implicates a new class of genes in arthritis progression, potentially opening doors to new treatment options.

17 Dec 2013

‘Window for intervention’ to forestall hypertensive cognitive decline

Newly diagnosed hypertension is predictive of cognitive decline in middle-aged individuals and is worse in those with poorly controlled blood pressure, Dutch researchers have found.

16 Dec 2013

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Can-Fite reports positive results from CF101 Phase IIb study for rheumatoid arthritis

Death rates two times higher in postmenopausal women with anti-CCP and RA antibodies

Six common diseases arise from DNA changes, finds new research

Antares Pharma receives Notice of Allowance for new patent application on reconstitutable drugs

Solana's CrossCHECK Plating System receives FDA clearance

Hispanic mortality paradox found in RA patients

Helsinn, Mundipharma sign distribution and license agreement for investigational therapy

Sanofi and Regeneron Pharmaceuticals team up with ACC to enhance clinical research with alirocumab

Regenerative medicine may offer ways to banish baldness

People with intermittent explosive disorder elevate levels of markers of systemic inflammation in blood

FDA accepts Regeneron's EYLEA Injection sBLA for standard review

Primary cilia play key role in stem cell differentiation

Chronic pain amongst different ethnic groups: an interview with Professor Martin Underwood, Warwick Medical School

Nonsurgical treatment of periodontal disease does not improve glycemic control in patients with diabetes

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Biogen joins with Samsung Bioepis to commercialize anti-TNF biosimilar product candidates in Europe

Scientists identify protein complex essential for jumpstarting immune response during infection

Utah researchers discover naturally occurring genetic variation that cause inflammatory arthritis

‘Window for intervention’ to forestall hypertensive cognitive decline

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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