Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Anti-epileptic drugs, bone loss and supplements

Antiepileptic drugs are medications used to prevent and control seizure disorders. These medications are also frequently used for other diagnoses other than seizures, however this current study concentrated on patients with a seizure disorder.

25 Nov 2013

EYLEA Injection gets approval in Japan for treatment of macular edema following CRVO

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has received approval for the treatment of Macular Edema Following Central Retinal Vein Occlusion from the Japanese Ministry of Health, Labour and Welfare.

22 Nov 2013

DNA-damaging drug and MK2 inhibitor combination could be effective against cancer

About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA.

20 Nov 2013

Study compares prevalence, impact of chronic pain amongst different ethnic groups in Tower Hamlets

A new study in the London Borough of Tower Hamlets, funded by medical research charity Arthritis Research UK, may help improve GPs’ understanding of chronic musculoskeletal pain amongst different ethnic groups and develop better strategies for self-management as a result

20 Nov 2013

Researchers discover new genetic risk factor for schizophrenia, bipolar disorder

Investigators at The Feinstein Institute for Medical Research have discovered a new genetic risk factor for schizophrenia and bipolar disorder called NDST3. The findings are published online in Nature Communications.

20 Nov 2013

Extract from bitter melon may have therapeutic qualities to treat head and neck cancer

Extract taken from an Asian vegetable may have therapeutic qualities to treat head and neck cancer, a Saint Louis University researcher has found.

19 Nov 2013

Grave prognosis for heart patients with treatment-resistant hypertension

Patients with coronary artery disease have a particularly high risk for poor outcomes if they have treatment-resistant hypertension, shows an analysis of the Treating to New Targets trial.

18 Nov 2013

Eisai partners with NewBridge Pharmaceuticals to market Halaven drug in Middle East

Eisai announces today that Halaven (eribulin) will be marketed in selected countries within the Middle East region through a new partnership between Eisai EMEA (Europe, the Middle East, Africa, Russia and Oceania) and NewBridge Pharmaceuticals.

18 Nov 2013

Study shows chronic diseases have strong negative impact on cancer survival rate

There are many people in this position and the number is increasing; cancer patients who not only have to fight against cancer, but also suffer from other diseases. So-called comorbidity is a large and growing problem, not least because we are becoming older and age increases the risk of contracting cancer as well as other diseases.

16 Nov 2013

Researchers examine effectiveness of calorie labels at fast-food chains

Posting the calorie content of menu items at major fast-food chains in Philadelphia, per federal law, does not change purchasing habits or decrease the number of calories that those customers consume, researchers at NYU Langone Medical Center reported today at the Obesity Society's annual scientific meeting, held in Atlanta, Georgia. The results echo those conducted by the same researchers among low-income neighborhoods in New York City before and after calorie-labels were mandated there in July 2008.

16 Nov 2013

Mayo Clinic Cardio-Rheumatology Clinic created for catching heart disease early in arthritis patients

Patients with rheumatoid arthritis, lupus and other chronic forms of inflammatory arthritis can face life-threatening complications, and heart disease tops the list. People with such rheumatic diseases are twice as likely as the average person to develop heart problems.

15 Nov 2013

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research from postdoctoral fellow Lick Lai in the lab of USC scientist Andy McMahon published in Proceedings of the National Academy of Sciences (PNAS) sheds light on how this important protein keeps people organized on a basic level by promoting orderly skeletal growth and preventing skeletal tumors.

15 Nov 2013

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Signum Dermalogix, Inc. announced that the National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the company a Small Business Innovation Research Phase II grant totaling $1.6 million for the development of a topical drug candidate for atopic dermatitis.

15 Nov 2013

Cells sticking molecule over-produced in rheumatoid arthritis and cancers

A molecule that helps cells stick together is significantly over-produced in two very different diseases - rheumatoid arthritis and a variety of cancers, including breast and brain tumors, concludes a new study. The scientists who made the discovery also found candidate drugs to inhibit the molecule, cadherin-11, one of which is already in a clinical trial.

14 Nov 2013

Skeletal problems now added to list of diabetes complications

The list of complications from type 2 diabetes is long: vascular and heart disease, eye problems, nerve damage, kidney disease, hearing problems and Alzheimer's disease. Physicians have long thought of osteoporosis as another outcome. Based on a Mayo Clinic study published in the Journal of Bone and Mineral Research, that's confirmed: You can definitely add skeletal problems to that list.

14 Nov 2013

Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

Collaborating with researchers from the Northwestern University Feinberg School of Medicine in Chicago, a research team at Wayne State University's School of Medicine led by Kezhong Zhang, Ph.D., has contributed to an important discovery in the inflammatory stress mechanism and specific inhibitor for the treatment of rheumatoid arthritis.

13 Nov 2013

Infection prevention: an interview with Dr. Robert Gorab, Chief Medical Officer, Hoag Orthopedic Institute

HOI has one of the lowest if not the lowest surgical readmission rate in the State of California. Our all-cause readmission rate is 3.3% and our joint replacement readmission was at 1.8% based on published CMS reports we received in September 2013.

12 Nov 2013

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Northwestern Medicine- scientists have successfully tested a nontoxic therapy that suppresses Lupus in blood samples of people with the autoimmune disease.

12 Nov 2013

Gene mutations responsible for persistent AD in African American children

Two specific genetic variations in people of African descent are responsible for persistent atopic dermatitis (AD), an itchy, inflammatory form of the skin disorder eczema. A new report by researchers in the Perelman School of Medicine at the University of Pennsylvania found that loss-of-function mutations to Filaggrin-2 (FLG2), a gene that creates a protein responsible for retaining moisture and protecting the skin from environmental irritants, were associated with atopic dermatitis in African American children.

12 Nov 2013

Metabolic syndrome components signal resistant hypertension

Chinese patients with hypertension that is difficult to treat often have poor cardiometabolic profiles, shows an analysis of the HOT-CHINA study.

11 Nov 2013

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Anti-epileptic drugs, bone loss and supplements

EYLEA Injection gets approval in Japan for treatment of macular edema following CRVO

DNA-damaging drug and MK2 inhibitor combination could be effective against cancer

Study compares prevalence, impact of chronic pain amongst different ethnic groups in Tower Hamlets

Researchers discover new genetic risk factor for schizophrenia, bipolar disorder

Extract from bitter melon may have therapeutic qualities to treat head and neck cancer

Grave prognosis for heart patients with treatment-resistant hypertension

Eisai partners with NewBridge Pharmaceuticals to market Halaven drug in Middle East

Study shows chronic diseases have strong negative impact on cancer survival rate

Researchers examine effectiveness of calorie labels at fast-food chains

Mayo Clinic Cardio-Rheumatology Clinic created for catching heart disease early in arthritis patients

Research sheds light on how protein keeps people organized by promoting orderly skeletal growth

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Cells sticking molecule over-produced in rheumatoid arthritis and cancers

Skeletal problems now added to list of diabetes complications

Researchers identify specific IRE1a inhibitor for rheumatoid arthritis treatment

Infection prevention: an interview with Dr. Robert Gorab, Chief Medical Officer, Hoag Orthopedic Institute

Nontoxic therapy shows encouraging results in blood samples from lupus patients

Gene mutations responsible for persistent AD in African American children

Metabolic syndrome components signal resistant hypertension

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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