Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

An abnormally suppressed immune system may be to blame in some cases of long COVID-19

A UCLA-led team of researchers studying the effect of the monoclonal antibody Leronlimab on long COVID-19 may have found a surprising clue to the baffling syndrome, one that contradicts their initial hypothesis.

22 Apr 2022

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

We speak with postdoctoral researcher Erola Pairo-Castineira about her recent work which aimed to find the genetic factors that may predispose individuals to critical COVID-19 and learn how COVID-19 affects cells in the body.

22 Apr 2022

New technology enables single-cell sorting based on functional outputs

For nearly 40 years, drugmakers have used genetically engineered cells as tiny drug factories. Such cells can be programmed to secrete compounds that yield drugs used to treat cancer and autoimmune conditions such as arthritis.

20 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

Researchers investigated the longevity and intensity of the SARS-CoV-2 vaccine immune response in patients suffering from immune-mediated inflammatory diseases.

15 Apr 2022

Crucial blood tests for celiac disease could help shrink the gap to diagnosis and improve care

The Canadian Celiac Association (CCA) hopes that an Ontario Ministry of Health pilot program which includes providing funding for crucial blood tests for celiac disease will be made permanent, to ensure ongoing screening of the 1 in 117 Ontarians at risk for the autoimmune disorder.

11 Apr 2022

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

New findings from the ongoing Drug Repurposing for Effective Alzheimer's Medicines (DREAM) study suggest that certain rheumatoid arthritis drugs may lower incidence of Alzheimer's disease and related dementias in people with cardiovascular disease.

8 Apr 2022

Study: Many older adults are not prescribed disease-modifying drugs for rheumatoid arthritis

Despite guidelines that call for early and aggressive treatment of rheumatoid arthritis, a new study suggests many older adults are not prescribed disease-modifying medications for their inflammatory autoimmune disease.

8 Apr 2022

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

Most autoimmune diseases are easy to diagnose but hard to treat. A paper published today in Science proposes using your unique immune cell fingerprint to rapidly identify which treatments will work for your autoimmune disease.

7 Apr 2022

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Low-fat vegan diet improves joint pain in patients with rheumatoid arthritis

A low-fat vegan diet, without calorie restrictions, improves joint pain in patients with rheumatoid arthritis, according to a new study conducted by researchers at the Physicians Committee for Responsible Medicine and published in the American Journal of Lifestyle Medicine. Study participants also experienced weight loss and improved cholesterol levels.

4 Apr 2022

Case study of multi-system inflammatory syndrome in children in a fully vaccinated teenager

A new preprint describes the importance of recognizing this complication, reporting a case of MIS-C without a prior history of this infection.

4 Apr 2022

Research provides a roadmap for new therapies to treat chorioamnionitis

One of the serious complications that can occur during late pregnancy happens when the amniotic sac (also called the bag of waters) breaks too early, which can allow bacterial infections to cause dangerous tissue inflammation around the placenta.

30 Mar 2022

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

NYU Langone Health is joining a new National Institutes of Health (NIH)-sponsored program called Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases (AMP AIM) as a leading center to discover new targets for therapy in these diseases.

30 Mar 2022

$AI shows potential to aid clinicians in fracture diagnosis$

AI shows potential to aid clinicians in fracture diagnosis

Artificial intelligence (AI) is an effective tool for fracture detection that has potential to aid clinicians in busy emergency departments, according to a study in Radiology.

30 Mar 2022

Depression occurs independently of inflammation for many older people, study suggests

Multiple prior studies have found higher levels of inflammation in older individuals with depression. Now, a new Penn Medicine study has found that clinically depressed older individuals, on average, don't have elevated levels of inflammation if they don't already have other inflammatory conditions such as arthritis.

28 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

Novel ACL reconstruction technique in younger patients garners positive results two years post-surgery

A new study by researchers at Hospital for Special Surgery in New York City presented today at the American Academy of Orthopaedic Surgeons 2022 Annual Meeting found that a novel surgical technique performed during anterior cruciate ligament (ACL) reconstruction in certain younger patients garnered positive results two years post-surgery.

27 Mar 2022

Lettuce could protect astronauts from bone density loss in microgravity

Astronauts might one day grow and eat genetically modified plants to ward off disease associated with long spaceflights. Researchers at the University of California, Davis College of Engineering have developed a transgenic, or genetically modified, lettuce producing a drug to protect against bone density loss in microgravity.

22 Mar 2022

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

An abnormally suppressed immune system may be to blame in some cases of long COVID-19

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

New technology enables single-cell sorting based on functional outputs

Using customized 'mini-antibodies' to mitigate chronic inflammation

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease

Crucial blood tests for celiac disease could help shrink the gap to diagnosis and improve care

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

Certain antirheumatic drugs may lower incidence of Alzheimer's and related dementias in people with cardiovascular disease

Study: Many older adults are not prescribed disease-modifying drugs for rheumatoid arthritis

Unique immune cell fingerprint can help rapidly identify better treatment for autoimmune disease

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Low-fat vegan diet improves joint pain in patients with rheumatoid arthritis

Case study of multi-system inflammatory syndrome in children in a fully vaccinated teenager

Research provides a roadmap for new therapies to treat chorioamnionitis

NYU Langone joins NIH-sponsored program as leading center to discover new targets for autoimmune, inflammatory diseases

AI shows potential to aid clinicians in fracture diagnosis

Depression occurs independently of inflammation for many older people, study suggests

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

Novel ACL reconstruction technique in younger patients garners positive results two years post-surgery

Lettuce could protect astronauts from bone density loss in microgravity

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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