Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

COX-2 inhibitors prescribed to reduce gastrointestinal toxicity prior to the market withdrawals

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most popular treatment for arthritis - despite their association with gastrointestinal (GI) complications, including bleeding ulcers and death.

27 Jul 2006

US patent granted for 4SC's clinical Project

The Munich-based drug discovery and development company 4SC AG has been informed by the US Patent and Trademark Office (PTO) that the office has granted the patent with the US patent number 7,071,355.

27 Jul 2006

Increasing rates of diabetes among U.S. adults

Adults in the United States have increasingly become overweight or obese in recent years, according to a national survey conducted for Indiana University, dispelling the notion of a plateau and injecting a note of urgency into efforts to help Americans achieve a healthier weight.

26 Jul 2006

Heat sensitivity may make testicular cancer cells more susceptible to standard treatments and die off more readily

Experts at Johns Hopkins have linked scientific evidence spanning more than 30 years to suggest an explanation for why testicular cancer patients like seven-time Tour de France winner Lance Armstrong survive far better than patients with other advanced cancers.

26 Jul 2006

Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain

Chronic widespread pain, a common medical condition, can be difficult to treat and is often associated with fatigue, poor sleep and depression.

26 Jul 2006

Estradiol and its metabolites and their association with knee osteoarthritis

Osteoarthritis, which usually develops between the ages of 40 and 50, is more prevalent in women. It is thought that sex hormones may play a role in developing the disease, since they can be involved in inflammation of the tissues affected by it.

26 Jul 2006

Disease-specific gene expression profiles in patients with rheumatoid arthritis

They sleep together, eat together, and most people find it impossible to tell them apart. Identical twins who grow up together share just about everything, including their genes.

26 Jul 2006

Remicade receives European approval for treatment of psoriatic arthritis

Schering-Plough Corporation today announced that the European Commission has approved the use of Remicade (infliximab) as monotherapy in the treatment of active and progressive psoriatic arthritis (PsA) in patients who show intolerance to methotrexate or for whom methotrexate is contraindicated.

26 Jul 2006

NICE backs use of Enbrel and Raptiva to treat severe psoriasis

NICE has today issued guidance for the use of the targeted biological therapies, Enbrel (etanercept) and Raptiva (efalizumab), to treat adult patients with severe plaque psoriasis.

26 Jul 2006

Loss of Matrilin-3 gene leads to osteoarthritis

A gene that is associated with osteoarthritis and skeletal deformities in people has been shown to be responsible for preventing the onset of osteoarthritis in adult mice, according to a recent study led by Rhode Island Hospital.

24 Jul 2006

Eicosanoids and inflammatory response

Revolutionary new results concerning substances that play major roles in the inflammatory response have been published in the American scientific journal PNAS in two articles from Karolinska Institutet.

18 Jul 2006

Importance of T cells in the prevention of autoimmune diseases

Centenary scientist Associate Professor Barbara Fazekas de St. Groth, a leader in inflammatory bowel disease research, has demonstrated for the first time the important role of T cells in the prevention of autoimmune diseases in humans.

9 Jul 2006

Obese women at greater risk of disease and death

Experts say that obesity is a disease that now affects nearly one-third of the adult American population, approximately 60 million people, and the latest study on the condition suggests that health risks to women who are obese may have been underestimated.

6 Jul 2006

Bioengineered tissue implants regenerate damaged knee cartilage

Knee cartilage injuries can be effectively repaired by tissue engineering and osteoarthritis does not stop the regeneration process concludes research led by scientists at the University of Bristol.

5 Jul 2006

Celiac success: New enzyme efficiently degrades gluten

A new enzyme originally developed for commercial food processing turns out to also quickly and nearly-completely break down whole gluten molecules as well as the T cell stimulatory peptides that cause celiac disease, a digestive disease with no current effective treatment other than avoiding wheat, barley or rye products.

5 Jul 2006