CRISPR News and Research

Latest CRISPR News and Research

New genome editing technology achieves efficient and precise large DNA insertions

GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a new genome editing technology that achieves efficient and precise targeted insertion of large DNA segments in plants.

24 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

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20 Apr 2023

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

This paper discusses the use of RNA lipid nanoparticles for cancer immunotherapy, which has shown promising results in clinical use. However, only a small percentage of patients respond to existing immunotherapies, and the paper explores opportunities for improvement.

18 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Precise genome editing approach can correct mutation that causes sickle cell disease

Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct the mutation that causes sickle cell disease in a potentially curative approach.

18 Apr 2023

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive chemotherapy to kill the cancer.

17 Apr 2023

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes.

11 Apr 2023

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options.

11 Apr 2023

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

10 Apr 2023

New finding in roundworms upends classical thinking about animal cell differentiation

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

7 Apr 2023

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the CRISPR gene editing technology, scientists are revealing the evolution of the CRISPR-Cas proteins from their precursors.

7 Apr 2023

CRISPR News and Research

Latest CRISPR News and Research

New genome editing technology achieves efficient and precise large DNA insertions

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

Researchers discover the molecule responsible for guiding T cells toward tumors

Precise genome editing approach can correct mutation that causes sickle cell disease

Combination treatment could improve stem cell transplantation process for multiple myeloma patients

Optimized genome-editing method opens the door to more effective treatment of genetic diseases

Bonn researchers elucidate a mechanism underlying cisplatin resistance in testicular cancer

Using the gene-editing tool to model certain liver tumor subtypes

New finding in roundworms upends classical thinking about animal cell differentiation

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

UW researchers engineer stem cells that do not generate dangerous arrhythmias

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

Researcher calls evolutionary meddling with genes as "genetic welding"

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production