CRISPR News and Research

Latest CRISPR News and Research

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Discovery points to a new understanding of Stargardt disease progression

Using a new stem-cell-based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

Researchers set sights on a new therapeutic target for aggressive breast cancer

Researchers at VCU Massey Cancer Center have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options.

25 Oct 2022

Celebrating the Alderley Park Grand Opening

HQ Plasmid Center of Excellence based at UK life science hotspot now open for business.

From Charles Rivers Laboratories Cell and Gene Therapy 24 Oct 2022

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

In a new study, researchers introduced a compact rapid detection kit that tests for the monkeypox virus using a combination of RPA and CRISPR technology.

24 Oct 2022

Butterfly wing pattern ground plan is manipulated by non-coding regulatory DNA, study says

Butterfly wing patterns have a basic plan to them, which is manipulated by non-coding regulatory DNA to create the diversity of wings seen in different species, according to new research.

21 Oct 2022

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Mitochondria -; the organelles responsible for energy production in human cells -; were once free-living organisms that found their way into early eukaryotic cells over a billion years ago.

20 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Study identifies genetic variation that influences lithium-induced neural proliferation

Bipolar disorder, a neuropsychiatric condition that includes manic and depressive episodes, affects about 1% of the population and is strongly influenced by genetics.

18 Oct 2022

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

In a new study posted to the medRxiv* preprint server, researchers in China developed an MPXV assay combining clustered regularly interspaced short palindromic repeats and CRISPR-associated protein (CRISPR/Cas) and recombinase-aided amplification (RAA) for the first time.

18 Oct 2022

Transition in the management of COVID-19

A review of the current approaches to managing COVID-19, including diagnostic, therapeutic, and preventive measures.

16 Oct 2022

Largest academic collaboration aims to transform the treatment for pediatric cancers

The Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute and St. Jude Children's Research Hospital today announced the largest academic collaboration of its kind to transform and accelerate the identification of vulnerabilities in pediatric cancers and translate them into better treatments.

13 Oct 2022

CRISPR News and Research

Latest CRISPR News and Research

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Discovery points to a new understanding of Stargardt disease progression

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

New studies point to a broadly applicable treatment for neurodegenerative diseases

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Researchers set sights on a new therapeutic target for aggressive breast cancer

Celebrating the Alderley Park Grand Opening

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

Butterfly wing pattern ground plan is manipulated by non-coding regulatory DNA, study says

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Study identifies genetic variation that influences lithium-induced neural proliferation

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

Transition in the management of COVID-19

Largest academic collaboration aims to transform the treatment for pediatric cancers

Researchers receive $9 million grant to study how ‘jumping genes’ influence Alzheimer's disease

Precise DNA cleavage using new CRISPR-Cas approach

Researchers take new approach to studying the development of the human brain

New platform for gene editing may change the landscape of CRISPR-based therapeutics

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production