CRISPR News and Research

Latest CRISPR News and Research

Researchers find way to reverse clotting factor deficiency that triggers hemophilia A

Sufferers of hemophilia live in a perpetual state of stress and anxiety: their joints wear down prematurely and they have bleeding episodes that feel like they will never end. Their bodies lack the ability to make the clotting factor responsible for the coagulation of blood so any cut or bruise can turn into an emergency without immediate treatment.

24 Jul 2015

Georgia researchers develop new tools to genetically manipulate parasite that causes cryptosporidiosis

Researchers at the University of Georgia have developed new tools to study and genetically manipulate cryptosporidium, a microscopic parasite that causes the diarrheal disease cryptosporidiosis.

16 Jul 2015

Umeå University to present special Jubilee Award to Emmanuelle Charpentier at Annual Celebration Ceremony

Umeå University honours Professor Emmanuelle Charpentier for her pioneering research with the powerful discovery of CRISPR-Cas9, which has already been of great importance by providing new opportunities for Life Science research and its applications in Biology and Medicine. Umeå University will present a special Jubilee Award to Emmanuelle Charpentier

25 Jun 2015

Study opens new area of discovery for different aspects of cell biology, biomedical research

Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.

19 Jun 2015

Researchers create cell lines to study gene expression in precursor brown fat and white fat cells

Since the 2009 discovery that energy-burning brown fat can be active in adults, research has raced ahead to understand this tissue and exploit it to treat the epidemic of obesity. Active brown fat also may assist in directly easing the burden of diabetes and related metabolic diseases by lowering the levels of glucose and fatty acids in the bloodstream. But progress in studying human brown fat often has been slowed by difficulties in obtaining and studying samples of the human cells that develop into brown fat.

17 Jun 2015

Electroporation technique brings higher efficiency, higher throughput genome engineering in animal models

Jackson Laboratory researchers have shown that using an electric current to deliver the CRISPR/Cas9 system, in order to engineer genetic changes in laboratory mice, is highly efficient and significantly improves the system's throughput.

9 Jun 2015

New Tel Aviv University research introduces promising new tool to combat antibiotic-resistant pathogens

At its annual assembly in Geneva last week, the World Health Organization approved a radical and far-reaching plan to slow the rapid, extensive spread of antibiotic resistance around the world. The plan hopes to curb the rise caused by an unchecked use of antibiotics and lack of new antibiotics on the market.

5 Jun 2015

IDT to host instructive talk on accelerating synthetic biology at ASM General Meeting

Integrated DNA Technologies will host an instructive talk on accelerating synthetic biology at the American Society for Microbiology General Meeting in New Orleans, Louisiana on Sunday May 31, 2015 at 11am CDT.

From Integrated DNA Technologies 28 May 2015

Sex-determining gene in mosquitoes may help reduce disease transmission

Researchers with the Fralin Life Science Institute at Virginia Tech have identified a gene responsible for sex determination in mosquitoes that can transmit yellow fever, dengue, and chikungunya viruses.

22 May 2015

NAS, NAM launch major initiative to guide decision making on human gene-editing research

The National Academy of Sciences and the National Academy of Medicine are launching a major initiative to guide decision making about controversial new research involving human gene editing. Human gene-editing technologies, such as CRISPR-Cas9, may lead to promising new treatments for disease.

19 May 2015

HHMI selects two Boston University medical students to conduct full-time biomedical research

Two medical students from Boston University have been selected by the Howard Hughes Medical Institute to conduct full-time biomedical research in its Medical Research Fellows Program. Joseph Park and Jacqueline Estevez are two of the selected 68 top medical and veterinary students from 37 different schools in the United States to receive this honor.

14 May 2015

ISSCR calls for moratorium on human germline genome editing attempts in clinical practice

In response to an article published by Chinese scientists describing research that used gene editing technologies in human embryos, the International Society for Stem Cell Research has again called for a moratorium on attempts at human clinical germline genome editing while extensive scientific analysis of the potential risks is conducted, along with broad public discussion of the societal and ethical implications.

27 Apr 2015

Researchers reveal the precise mechanism used by bacteria to target invading viruses

One of the immune system's most critical challenges is to differentiate between itself and foreign invaders -- and the number of recognized autoimmune diseases, in which the body attacks itself, is on the rise.

17 Apr 2015

A beginner’s guide to CRISPR genome editing

In a recent DECODED Online entry, Integrated DNA Technologies (IDT), the world leader in oligonucleotide synthesis, provides an overview of the CRISPR/Cas9 system to scientists looking to enhance their genome modification strategy in model organisms or cell lines.

From Integrated DNA Technologies 14 Apr 2015

Researchers use new gene editing tool to cut HIV DNA

The virus that causes AIDS is an efficient and crafty retrovirus. Once HIV inserts its DNA into the genome of its host cells, it has a long incubation period, and can remain dormant and hidden for years.

10 Apr 2015

New approach could help identify novel drug targets to combat lethal fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal agents.

6 Apr 2015

MDC scientists find solution to increase efficiency of precise genetic modifications

CRISPR-Cas9 is a powerful new tool for editing the genome. For researchers around the world, the CRISPR-Cas9 technique is an exciting innovation because it is faster and cheaper than previous methods. Now, using a molecular trick, Dr. Van Trung Chu and Professor Klaus Rajewsky of the Max Delbrück Center for Molecular Medicine Berlin-Buch and Dr. Ralf Kühn, MDC and Berlin Institute of Health, have found a solution to considerably increase the efficiency of precise genetic modifications by up to eightfold.

30 Mar 2015

Researchers harness gene editing technique in mosquito that infects people with deadly diseases

Traditionally, to understand how a gene functions, a scientist would breed an organism that lacks that gene - "knocking it out" - then ask how the organism has changed. Are its senses affected? Its behavior?