Chromosome News and Research

Latest Chromosome News and Research

Protein plays unexpected role protecting chromosome tips

A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction complex, a team lead by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Aug. 13 edition of Molecular Cell.

13 Aug 2009

Discovery of genetic mutations that increase risk of schizophrenia

In collaboration with colleagues from across Europe, researchers from the University of Copenhagen and the Mental Health Services in the Capital Region of Denmark have found mutations in the human genome that lead to an increased risk of developing schizophrenia.

11 Aug 2009

Decode Genetics announces Q2 2009 financials

deCODE genetics (Nasdaq: DCGN) today announced its consolidated financial results for the quarter ended June 30, 2009. A conference call to discuss these results and recent developments in the company's business will be webcast live tomorrow, Tuesday, August 11, at 8:00am Eastern Daylight Time/12 noon GMT/1pm British Summer Time (details below).

10 Aug 2009

Unlikely genetic suspect implicated in Dandy-Walker malformation

A genetic search that wound its way from patients to mouse models and back to patients has uncovered an unlikely gene critically involved in a common birth defect which causes mental retardation, motor delays and sometimes autism, providing a new mechanism and potentially improving treatment for the disorder.

9 Aug 2009

Discovery of possible mechanisms to protect against genetic alterations, diseases

Peering into the DNA of tiny yeast, researchers at the Moores Cancer Center at the University of California, San Diego and the San Diego Branch of the Ludwig Institute for Cancer Research have pinpointed a large number of genes that can prevent a type of genetic rearrangement that may lead to cancer and other diseases.

6 Aug 2009

Smoking marijuana has toxic effects on cells

In a finding that challenges the increasingly popular belief that smoking marijuana is less harmful to health than smoking tobacco, researchers in Canada are reporting that smoking marijuana, like smoking tobacco, has toxic effects on cells.

6 Aug 2009

Protein DNA repair complex key to avoiding DNA repair mistakes

As the body creates antibodies to fight invaders, a three-protein DNA repair complex called MRN is crucial for a normal gene-shuffling process to proceed properly, University of Michigan research shows.

5 Aug 2009

New insight into human ciliopathy

In the September 1st issue of G&D, Dr. Karen Oegema (UCSD) and colleagues identify the molecular basis of the lethal developmental disorder, hydrolethalus syndrome, and reveal that hydrolethalus syndrome actually belongs to the emerging class of human ciliopathy diseases.

4 Aug 2009

Genetic link to ovarian cancer found

Scientists have located a region of DNA which - when altered - can increase the risk of ovarian cancer according to research published in Nature Genetics today.

3 Aug 2009

Discovery of key event in prostate cancer progression

A study led by researchers at the Ohio State University Comprehensive Cancer Center and Dana-Farber Cancer Institute reveals how late-stage, hormone-independent prostate tumors gain the ability to grow without need of hormones.

24 Jul 2009

National Institutes of Health develops research plan on Fragile X syndrome and associated disorders

The National Institutes of Health has developed a research plan to advance the understanding of fragile X syndrome and its associated conditions, fragile X-associated tremor/ataxia syndrome and fragile X-associated primary ovarian insufficiency. Fragile X syndrome causes intellectual and developmental disabilities and results from a mutation in a gene on the X chromosome.

20 Jul 2009

New discovery on DNA repair mechanism

Researchers at Washington University School of Medicine in St. Louis have shed new light on a process that fixes breaks in the genetic material of the body's cells. Their findings could lead to ways of enhancing chemotherapy drugs that destroy cancer cells by damaging their DNA.

17 Jul 2009

New research tool – map of genomic variation for diagnosing and identifying genetic problems

Genetics researchers have unveiled a powerful new resource for scientists and health providers studying human illnesses -- a reference standard of deletions and duplications of DNA found in the human genome. Drawn from over 2,000 healthy persons, the study provides one of the deepest and broadest sets of copy number variations (CNVs) available to date, along with a new research tool for diagnosing and identifying genetic problems in patients.

15 Jul 2009

Surprising new insights into the repair strategies of DNA

A microscopic single-celled organism, adapted to survive in some of the harshest environments on earth, could help scientists gain a better understanding of how cancer cells behave.

15 Jul 2009

Handle with care: Telomeres resemble DNA fragile sites

Telomeres, the repetitive sequences of DNA at the ends of linear chromosomes, have an important function: They protect vulnerable chromosome ends from molecular attack.

9 Jul 2009

Embryonic stem cells used to create human sperm

Human sperm have been created using embryonic stem cells for the first time in a scientific development which will lead researchers to a better understanding of the causes of infertility.

9 Jul 2009

Discovery of key gene for bone development that when mutated lead to dwarfism

Scientists have just discovered the gene behind Recessive Omodysplasia, a rare skeletal disease characterised by short-limbed dwarfism and craniofacial anomalies.

9 Jul 2009

DNA alterations on human chromosome 9 linked to glioblastoma

Mayo Clinic researchers and colleagues at the University of California San Francisco (UCSF) have found a connection between DNA alterations on human chromosome 9 and aggressive brain cancer known as glioblastoma. The findings are reported in the current online issue of Nature Genetics.

5 Jul 2009

Reduced ovarian reserve is associated with an increased risk of trisomic pregnancy

Women who have a diminished number of eggs in their ovaries, either because they are older or for some other reason such as ovarian surgery, may be more at risk of a trisomic pregnancy than women with an ovarian reserve within the normal, fertile range.

30 Jun 2009

New test detects genetic and chromosomal abnormalities in embryos - ready for clinical trials

One-step screening for both genetic and chromosomal abnormalities has come a stage closer as scientists announced that an embryo test they have been developing has successfully screened cells taken from spare embryos that were known to have cystic fibrosis.

30 Jun 2009