Cirrhosis News and Research

Latest Cirrhosis News and Research

King's College researchers awarded £2.3 million for new trial to treat liver disease

Dr Mark McPhail from the Department of Inflammation Biology, School of Immunology & Microbial Sciences and Dr Vishal Patel from the Institute of Liver Studies at King's College Hospital have been awarded £2.3 million by the National Institute of Health Research Health Technology Assessment to lead a new UK wide multi-centre trial to treat liver disease.

9 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers at Northeast Ohio Medical University studied the lifespan of mitochondrial proteins in a mouse model of fatty liver disease. Comparing the amount of protein between healthy mice and a mouse model of nonalcoholic fatty liver disease gave them an estimate of each protein's half-life.

17 Sep 2018

Shionogi launches Mulpleta in the U.S for safe, effective treatment of thrombocytopenia

Shionogi & Co., Ltd. announced today that Mulpleta (lusutrombopag), a once-daily, orally administered, small molecule thrombopoietin (TPO) receptor agonist for the treatment of thrombocytopenia in adult patients with chronic liver disease (CLD) who are scheduled to undergo a procedure, is now available throughout the United States.

30 Aug 2018

Routine oral care to treat gum disease may improve cognitive function in cirrhosis patients

Routine oral care to treat gum disease may play a role in reducing inflammation and toxins in the blood and improving cognitive function in people with liver cirrhosis.

29 Aug 2018

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Pulmonary fibrosis is one of the most common and serious types of lung disease. Now NIBIB-funded researchers have developed an in vitro lung tissue-on-a-chip system that mimics lung fibrosis, offering rapid testing of potential new anti-fibrotic treatments.

28 Aug 2018

Newly discovered target may prevent progression of liver injury to cancer

Problems like obesity and alcoholism appear to chronically trigger in the liver a receptor known to amplify inflammation in response to invaders like bacteria, scientists report.

27 Aug 2018

Surgeons test new device that keeps the liver warm and circulates blood during transport

Since the first liver transplant in 1963, donated livers have been immersed in an icy cold fluid in a cold storage system for transport, similar in principle to ice chests used for picnics and trips to the beach.

25 Aug 2018

Researchers win multi-million Euro award to conduct research into liver disease

A team of researchers from the School of Immunology and Microbial Sciences and the Dental Institute has secured a multi-million Euro award to conduct research into liver disease.

16 Aug 2018

FDA approves first vaginal ring contraceptive that can be used for one year

The U.S. Food and Drug Administration today approved Annovera (segesterone acetate and ethinyl estradiol vaginal system), which is a combined hormonal contraceptive for women of reproductive age used to prevent pregnancy and is the first vaginal ring contraceptive that can be used for an entire year.

10 Aug 2018

FIND and genedrive announce study agreement to evaluate HCV ID Kit

genedrive plc, a near patient molecular diagnostics company, and the Foundation for Innovation of New Diagnostics (FIND), announced today a study agreement for the performance evaluation of genedrive plc’s hepatitis C virus (HCV) Genedrive HCV ID Kit.

10 Aug 2018

Scientists identify two potential new drug targets for treatment of HIV

Johns Hopkins scientists report they have identified two potential new drug targets for the treatment of HIV. The finding is from results of a small, preliminary study of 19 people infected with both HIV - the virus that causes AIDS - and the hepatitis C virus.

7 Aug 2018

Genetic factors may play a role in progression of liver injury in Caucasians with hepatitis B infection

A new study has shown that genetic variation may increase the risk of severe liver damage in Caucasians with chronic hepatitis B infection.

27 Jul 2018

Researchers emphasize need for baby boomers to get tested for hepatitis C

According to the Centers for Disease Control and Prevention, 300 million people across the globe are unaware they're living with viral hepatitis. In fact, baby boomers - those born between 1945-1965 - are five times more likely to have hepatitis C, one of the many different strains of this viral infection.

27 Jul 2018

Bile acids from the gut may offer new treatment for cocaine abuse

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a study publishing on July 26 in the open-access journal PLOS Biology by India Reddy, Nicholas Smith, and Robb Flynn of Vanderbilt University, Aurelio Galli of the University of Alabama at Birmingham, and colleagues.

27 Jul 2018

Study finds link between DNA methylation and non-alcoholic fatty liver disease

DNA methylation is a molecular process that helps enable our bodies to repair themselves, fight infection, get rid of environmental toxins, and even to think. But sometimes this process goes awry.

19 Jul 2018

Alcohol-related cirrhosis mortality on the rise among young adults

Deaths from cirrhosis rose in all but one state between 1999-2016, with increases seen most often among young adults, a new study shows.

19 Jul 2018

Health burdens of very high risk drinking are potentially large, study reveals

In an Addiction Biology study, the estimated prevalence of very high risk drinking level (VHRDL, defined as drinking >100 g of ethanol per day) in 13 European Union countries was 0.74-0.85 percent, with a risk of disease or injury of 13.5 per 100 people with VHRDL per year.

18 Jul 2018

Researchers find experimental compound to treat fibrotic diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases - kidney, liver and lung fibrosis -- the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal.

13 Jul 2018

Study: Hepatitis C vaccine could drastically reduce transmission among injecting drug users

Among the most serious consequences of the opioid epidemic is the spread of hepatitis C among injecting drug users.

12 Jul 2018

Cirrhosis News and Research

Latest Cirrhosis News and Research

King's College researchers awarded £2.3 million for new trial to treat liver disease

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

New studies examine links between fatty liver disease and mitochondrial dysfunction

Shionogi launches Mulpleta in the U.S for safe, effective treatment of thrombocytopenia

Routine oral care to treat gum disease may improve cognitive function in cirrhosis patients

New lung tissue-on-a-chip system offers rapid testing of potential anti-fibrotic treatments

Newly discovered target may prevent progression of liver injury to cancer

Surgeons test new device that keeps the liver warm and circulates blood during transport

Researchers win multi-million Euro award to conduct research into liver disease

FDA approves first vaginal ring contraceptive that can be used for one year

FIND and genedrive announce study agreement to evaluate HCV ID Kit

Scientists identify two potential new drug targets for treatment of HIV

Genetic factors may play a role in progression of liver injury in Caucasians with hepatitis B infection

Researchers emphasize need for baby boomers to get tested for hepatitis C

Bile acids from the gut may offer new treatment for cocaine abuse

Study finds link between DNA methylation and non-alcoholic fatty liver disease

Alcohol-related cirrhosis mortality on the rise among young adults

Health burdens of very high risk drinking are potentially large, study reveals

Researchers find experimental compound to treat fibrotic diseases

Study: Hepatitis C vaccine could drastically reduce transmission among injecting drug users

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Cirrhosis News and Research

Latest Cirrhosis News and Research

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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